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All Journal Jurnal Ilmiah Pertanian JOPS (Journal Of Pharmacy and Science) JPK: Jurnal Proteksi Kesehatan Ebima : Edukasi Bidan di Masyarakat PITIMAS: Journal of Community Engagement in Health
Uthia, Rahimatul
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Journal : JPK: Jurnal Proteksi Kesehatan

 1 
TERATOGENEOUS EFFECTS OF GYNURA PROCUMBENS (LOUR.) MERR. ETHANOL EXTRACT AGAINST MUS MUSCULUS FETAL Uthia, Rahimatul; Anggraini, Riza; Fauziah, Fitra; Rz, Ira Oktaviani
JURNAL PROTEKSI KESEHATAN Vol 9 No 1 (2020): JPK: Jurnal Proteksi Kesehatan
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (732.675 KB) | DOI: 10.36929/jpk.v9i1.230

Abstract

This study looked at the teratogenous effects of ethanol extracts of Gynura procumbens (Lour.) Merr. on the white mice fetus. Experimental animals consisted of 24 mices, 4 male mices and 20 female mices, divided into 4 groups, namely the negative control group, ethanol extracts of Gynura procumbens (Lour.) Merr. 150 mg/kg BW; 300 mg/kg BW; and 600 mg/kg BW. Provision is made from the 6th day until the 15th day of pregnancy. Laparactomy is carried out on the 18th day of pregnancy. The parameters observed were body weight of mices, number of fetuses, average fetal weight, and macroscopic observation of the fetus. The results showed that the parent's body weight, number of fetuses, and average fetal weight were significantly different (sig <0.05). Macroscopic observation of the fetus obtained slow growth in ethanolic extracts dose of 600 mg/kgBW. This study can be concluded that the ethanol extract of Gynura procumbens (Lour.) Merr.has a teratogenic effect on the fetus of white mice.
Co-Authors Anggraini, Riza Ari Susanti DELVIRA, WIWIEK Elmukhsinur, Elmukhsinur Fathul Jannah, Fathul Fauziah, Fitra Hidayani, Sri Vina Idayanti Idayanti Lestari, Kustiasih Rosy, Alice rz, ira oktaviani Syafrisar Meri Agritubella