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All Journal HAYATI Journal of Biosciences Jurnal Kedokteran Brawijaya Research Journal of Life Science Majalah Kesehatan FKUB Journal of Issues in Midwifery
Mayangsari, Elly
Department Of Pharmacology, Faculty Of Medicine, Universitas Brawijaya, Malang, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Medicine & Pharmacology Nursing Public Health

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Journal : Journal of Issues in Midwifery

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Pengaruh Pemberian Air Tape Ketan Putih terhadap Kadar Hemoglobin Tikus Rattus norvegicus Bunting Laili, Sauli Nur; Mayangsari, Elly; Rahayu, Indriati Dwi
Journal of Issues in Midwifery Vol 2, No 2 (2018)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.996 KB) | DOI: 10.21776/ub.JOIM.2018.002.02.2

Abstract

Tape merupakan hasil proses fermentasi yang akan menghasilkan alkohol. Pada beberapa daerah, banyak larangan ibu hamil untuk mengkonsumsi tape karena dipercaya dapat menyebabkan keguguran. Keguguran merupakan salah satu dampak dari anemia. Oleh karena itu penelitian ini bertujuan untuk mengetahui pengaruh pemberian air tape ketan putih terhadap kadar hemoglobin pada tikus Rattus novegicus bunting. Penelitian ini menggunakan desain experimental sejati dengan rancangan penelitian Post Test Only Control Group Design. Sampel yang digunakan sebanyak 20 tikus bunting yang dibagi menjadi 4 kelompok; kelompok kontrol (K), kelompok perlakuan dengan 3 dosis air tape ketan putih dengan kadar 2,79% (P1=20 ml/kgBB, P2=30 ml/kgBB, P3=40 ml/kgBB). Air tape ketan putih diberikan hari pertama sampai hari ke-19 kebuntingan. Kemudian pada hari ke-20 tikus dikorbankan dan diambil darahnya dari jantung untuk penghitungan kadar hemoglobin. Hasil pada penelitian ini menunjukkan bahwa kadar hemoglobin setelah perlakuan menunjukkan kecenderungan menurun tetapi tidak berbeda secara signifikan p = 0,1 (p>0,05). Namun berdasarkan hasil uji d-type effect size pada P3 menunjukkan pengaruh yang sangat besar dengan ES = 1.40540541 dalam menurunkan kadar hemoglobin. Hasil uji korelasi pearson p= 0,017 (p<0,05) menunjukkan ada hubungan yang cukup kuat dan berlawanan arah p=– 0,529 (p>0,5). Kadar hemoglobin setelah perlakuan menunjukkan kecenderungan menurun tetapi tidak berbeda secara signifikan. Kata kunci: hamil,air tape ketan putih, kadar hemoglobin
Efek Pemberian Jus Paprika Merah (Capsicum annuum L.) Terhadap Kadar Kolesterol Tikus Putih (Rattus norvegicus) Bunting Larasati, Sasmita Dyah; Mayangsari, Elly; Fatmawati, Fatmawati
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Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.JOIM.2020.004.02.2

Abstract

ABSTRACTDuring pregnancy, the cholesterol level in pregnant women can increase by 50-60%. This increase has occurred since the second trimester and continue to increase until the third trimester. Continuous increase in cholesterol level can causes cholesterol build up in blood vessels so that il narrows the blood vessels which can causes atherosclerotic. In this increase of cholesterol level can be suppressed by choosing the right foods, one of them is consumption of foods that contain vitamin C. Red Paprika is one of the foods that contain high vitamin C, where vitamin C inhibits the work of HMG Ko-A reduktase which play a role in enzyme in the synthesis of cholesterol. The study aims to determine the effect of red paprika juice administration to cholesterol level of pregnant rat. This study used 24 white rats with randomly divided groups into 4 group, the control group, treatment 1 with a dose of 0.85 cc (95 gr), treatment 2 with a dose of 1.7 cc (1.9 gr), treatment 3 with a dose of 3.4 cc (3.8 gr) per head per day. Cholesterol level obtained in this study were cholesterol obtained on first day and the nineteenth days of pregnancy. The post hoc test result showed P1 p=0.33, P2 p=0.008, P3 p=0.008 paired with the control group. The ANOVA test result showed significant result, p=0.004 (p<0.05). in this study it can be concluded that administration of red paprika juice can reduce the cholesterol level in pregnant rats.
Pengaruh Pemberian Sari Ketela Ungu (Ipomea Batatas L.) Terhadap Kadar Insulin Tikus Wistar Bunting Model DMG Ningrum Irfandi Putri, Nur Ilmya Nugraha; Mayangsari, Elly; Dewi, Mustika
Journal of Issues in Midwifery Vol. 7 No. 2 (2023)
Publisher : Journal of Issues in Midwifery

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.JOIM.2023.007.02.2

Abstract

Background : Gestational Diabetes Mellitus is a complication of pregnancy in mothers without a previous diagnosis of diabetes, then chronic hyperglycemia is detected during pregnancy. Generally, this hyperglycemia is caused by impaired glucose tolerance due to pancreatic cell dysfunction, which begins with chronic insulin resistance conditions. The prevalence of GDM in Southeast Asia is 10%, while the overall diagnosis of diabetes in women in Indonesia is 1.8%. Nowadays, antioxidant therapy is being developed to treat DMG, one of which is the use of purple cassava plants.Objective : to determine the effect of purple cassava juice (Ipomea Batatas L.) on increasing insulin levels of wistar rats model of gestational diabetes mellitus. Methode : This study used an experimental method which was designed with the Post Test Only Group Design method. The total number of samples used in this study was 30 rats which were divided into 5 groups. Furthermore, the treatment group was given STZ injection of 45 mg/KgBB and then given purple cassava juice therapy for 14 days. Next, blood samples were tested for insulin levels using the ELISA Rat Kit. Result : There are no differences of insulin level between the treatment group and the control group because they had constant result. Conclusion : In this study, it was not found that there was an increase in insulin levels after treatment of purple yam juice for 14 days. So the research hypothesis was rejected. Keyword : Diabetes Mellitus Gestasional, Insulin Levels, Wistar Rats, Purple Yam Juice.
Co-Authors A.A. Ketut Agung Cahyawan W Adinda Chika Anindita Binti Razali, Nately Diana Chikita, Gauca Syadzaiffat Dian Nugrahenny Dicky Faizal Irnandi Edwin Widodo Fadriyana, Aulia Putri Fardizia Putri Alia Fatmawati Fatmawati Happy Kurnia Permatasari Hermanto, Djoko Heri Hidayat Sujuti Ihda Dian Kusuma Indriati Dwi Rahayu Indriati Dwi Rahayu Karyono Mintaroem Laili, Sauli Nur Larasati, Sasmita Dyah Lavina Sofia Ardani Mustika Dewi Nathania Bella Claresta Niarti Ulan Sari Siarnu Ningrum Irfandi Putri, Nur Ilmya Nugraha Nur Permatasari Nura Fattah Cantika Yoga Pragiwaksana, R. Galih Agung Rahmad Rahmad Retty Ratnawati Santosa, I Putu Adi Setyawati Soeharto Setyawati Soeharto Tika Ardhini Wardoyo