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Journal : Jurnal Ilmu dan Teknologi Kesehatan

Comparison of TSH Levels Pulmonary Tuberculosis Patients at The Phase 0 and 6 Months Treatment Qo'imah, Alamanda Nurul; Wardani, Dita Pratiwi Kusuma; Sudarsono, Tantri Analisawati; Mulyanto, Arif
jitek Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.910

Abstract

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Pulmonary TB has become a health problem worldwide, including in Indonesia, because the sufferers' prevalence is increasing every year. The increase in TB drug resistance will pose a severe health threat. The continuous consumption of drugs in large quantities and high doses can affect the function of the thyroid gland. This study aimed to determine the levels of thyroid stimulating hormone (TSH) in pulmonary tuberculosis patients with treatment phases of 0 months and six months. This research is analytical observational research with a cross-sectional research design. The sampling method uses accidental sampling. A total of 42 respondents participated in this study to determine the levels of TSH in pulmonary TB. The results of the Mann-Whitney U test showed no difference in TSH levels in pulmonary TB patients with different treatment phases of 0 months and six months (p = 0.3). There was no significant difference between TSH levels in pulmonary TB patients in the 0 and 6-month treatment phases.
Comparison of Ureum and Creatinine Levels Pulmonary Tuberculosis in Phase 0 and 6 Moths Treatment Aprianto, Aprianto; Sudarsono, Tantri Analisawati; Kusuma Wardani, Dita Pratiwi; Rahaju, Minto
jitek Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.927

Abstract

Pulmonary tuberculosis is a disease caused by Mycobacterium tuberculosis. Treatment for tuberculosis patients is given in the intensive and advanced stages. Anti-tuberculosis drugs can be nephrotoxic to cells in the kidneys. This research is an analytic observational study to know the comparison of urea and creatinine levels in pulmonary tuberculosis patients in the 0 and 6-month treatment phases at the Community Lung Health Center Purwokerto. The samples studied were 42 respondents who were taken by accidental sampling. This study was conducted from December 2021 to January 2022. Out of the 42 pulmonary tuberculosis patients who received treatment at 0 and 6 months, the majority of pulmonary tuberculosis patients were 28 patients (66.7%) had normal urea levels, and 38 patients (90.5 %) had normal creatinine levels. Urea levels in pulmonary tuberculosis patients during the 0-month treatment phase were 9 (2-24) mg/dL, while in the 6-month treatment phase, it was 8 (1-37) mg/dL. The creatinine level of pulmonary tuberculosis patients with 0-month treatment phase was 0.98 (0.64-1.62) mg/dL, while in the 6-month treatment phase it was 0.88 (0.62-1.92) mg/dL. There was no significant comparison of urea and creatinine levels in pulmonary tuberculosis patients with treatment phases 0 and 6 months (p>0.05).
Relationship Between Results of Genexpert RT-PCR and Erythrocyte Sedimentation Rate in Suspected Tuberculosis Patients Listiyowati, Tanti; Wardani, Dita Pratiwi Kusuma; Sudarsono, Tantri Analisawati; Wijayanti, Linda
jitek Vol 10 No 2 (2023): Maret 2023
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i2.1078

Abstract

Pulmonary tuberculosis (TB) is an infectious disease that attacks the lungs and is caused by the bacterium Mycobacterium tuberculosis. The GeneXpert RT-PCR examination (Xpert MTB / RIF) is a development of a diagnostic tool that can automatically detect the presence of Mycobacterium tuberculosis (MTB) by molecular examination and can be used to detect MTB resistance to rifampicin. Erythrocyte sedimentation rate (ESR) is a test used to determine the rate at which erythrocytes settle in the blood. The purpose of this study was to determine the relationship between GeneXpert RT-PCR results and ESR in suspected tuberculosis patients. This research uses a cross-sectional study. The sample used in this study were 56 new suspected TB patients who had never been treated for ATD and underwent GeneXpert RT-PCR examination. Sampling was carried out by purposive sampling with the TCM Rif Sen group and negative results. A total of 27 patients (96.4%) with Rif Sen's GeneXpert RT-PCR results had high ESR values. 15 patients (53.6%) with negative GeneXpert RT-PCR results had normal ESR values. The results of the Chi Square test (X2) show that p-value = 0.000 OR = 0.032. There is a significant relationship between GeneXpert and ESR values ​​in suspected tuberculosis