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Journal : JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL

FORMULASI SEDIAAN SAMPO ANTIKETOMBE EKSTRAK DAUN ALPUKAT (Persea americana Mill) DAN UJI AKTIVITASNYA TERHADAP JAMUR Pityrosporum ovale Mainal Furqon; Silitonga, Evawani Martalena; Br Tarigan, Frida Lina; Rini
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 3 No. 2 (2021): JURNAL TEKNOLOGI, KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Avocado leaves have antifungal activity because they contain chemical compounds. This study aims to determine whether avocado leaf ethanol extract (Persea americana Mill) can be formulated info anti-dandruff shampoo preparations and determine whether avocado leaf ethanol extract ethanol has antifungal activity against pityrosporum ovale. This research is experimental in the form in the form of an organoleptic test, the results were obtained with a liquid form slightly thick with the smell of avocado extract and blackish brown in color the homogeneity test on the 4 preparations was obtained homogeneous. In the Ph test, the ph for F0 7 and FI, F2, and F3 was obtained 6. The foam heights were 11 cm, while at F2 and F2, and F3, it was 9 cm. The stabilility test. Were was no change in the preparation, and for the irritation test there was no change. Allergic to the respondent. Shampoo activity test on the four preparations obtained inhibition zones in shampoo preparations with can be concluded that avocado leaf extract shampoo has antifungal activity against the fungus pityrosporum ovale.
Aktivitas Antibakteri Minyak Atsiri Buah Andaliman (Zanthoxylum acanthopodium DC) Terhadap Bakteri Streptococcus mutans dan Propionibacterium acne Fitri, Widya; Tarigan, Yenni Gustiani; Silitonga, Evawani Martalena; Telambenua, Fiki julfitra
JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS) Vol. 4 No. 1 (2022): JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS)
Publisher : Universitas Sari Mutiara Indonesia

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Abstract

Andaliman fruit is a cultivation plant that functions as an antibacterial. Streptococcus mutans is a bacterium that causes dental caries which causes damage to hard tissues. Acne propionibacterium Is a bacterium that causes skin diseases that cause inflammation of tissues associated with immune systems and supports inflammation of acne. Clindamicin is a broad spectrum broad-spectrum bacteriostatic antibiotic that is active against aerobic and anaerobic microorganisms, positive and negative bacteria. Isolation of andaliman fruit essential oil using the air distillation method using a stahl tool. Antibacterial activity test using disc diffusion on MHA media by determining the diameter of the inhibition zone. The concentration of andaliman fruit essential oil used was 2.5%, 5%, 10%, 20% and 40%, with n-hexane p.a solvent and clindamicin concentration 30 μg / ml which was used as a comparison with aquadest solvent. The results showed the diameter of the combined inhibitory zones in Streptococcus mutans bacteria. With a concentration of 2.5% inhibition zone 8.8 mm, inhibition zone 5% 9.0 mm, 10% inhibition zone 10.1 mm, 10% inhibition zone 11.1 mm, 40% 14.5. In acne bacteria Propionibacterium. 2.5% inhibition zone 9.1 mm, 5% inhibition zone 9.2 mm, 10% inhibition zone 10.3 mm, 20% inhibition zone 12.6 mm, 40% 14.1. And clindamicin as a comparison has a 30.6 mm inhibitory zone in acne Propionibacterium bacteria and in Streptococcus mutans. 29.2 mm. From the results of the antibacterial activity test of andaliman essential oil at a concentration of 2.5%, 5%, 10%, 20% and 40%, able to inhibit the growth of Streptococcus mutans and Propionibacterium acne. The results of isolation of Andaliman fruit essential oil by using the Stahl tool are available 4.76% essential oil