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All Journal Majalah Kesehatan FKUB Bina Teknika Kumawula: Jurnal Pengabdian Kepada Masyarakat Medika Kartika : Jurnal Kedokteran dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Andalas obstetrics and gynecology journal Jurnal Kesehatan Pasak Bumi Kalimantan International Journal of Multidisciplinary: Applied Business and Education Research Journal of Community Engagement Research for Sustainability Jurnal Pengabdian Kepada Masyarakat Mulawarman Indonesian Journal of Cancer Greenation International Journal of Engineering Science Greenation International Journal of Engineering Science
Saputra, Rudi
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Journal : Jurnal Kesehatan Pasak Bumi Kalimantan

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Association of Multidrug-Resistant Tuberculosis (MDR-TB) Patients on Profile of Liver and Kidney Function Muda, Iskandar; Adam, Muhammad Fadlan; Saputra, Rudi; Muhyi, Annisa; Noprianto, Dwi; Aminuddin, Muhammmad
Jurnal Kesehatan Pasak Bumi Kalimantan Vol 5, No 2 (2022): JKPBK Desember 2022
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/j.kes.pasmi.kal.v5i2.9640

Abstract

Introduction: Therapy of multidrug-resistant tuberculosis (MDR-TB) patients is still not handled properly, is more toxic, and is more high-priced. The liver is the primary metabolism, and the kidney is the main excretion organ. The study aims to know the association of multidrug-resistant tuberculosis (MDR-TB) patients on profile of liver and kidney function Methods: The research is a cross-sectional study with consecutive sampling. Twenty-four respondents were confirmed as MDR-TB patients without HIV who had done biochemical tests. Results: We found that sex of MDR-TB patients on liver function; ALT (p = 0.124) and AST (p = 0.077) and kidney function; BUN (p = 0.270), creatinine (p = 0.137).  Age of MDR-TB patients on liver function; ALT (p = 0.587) and AST (p = 0.093) and kidney function; BUN (p = 0.423), creatinine (p = 0.142). Comorbid on MDR-TB patients on liver function; ALT (p = 0.756) and AST (p = 0.244) and kidney function; BUN (p = 0.816), creatinine (p = 0.612). Conclusions: There were no association in sex, age, and comorbid of MDR-TB on liver and kidney function.
Sunlight, Vitamin D, and Depressive Disorders: A Literature Review Salsabila, Naila Cantika; Saputra, Rudi; Khairiah, Siti; Nuryanto, Muhammad Khairul; Aminyoto, Meiliati; Fadilah, Syaiful
Jurnal Kesehatan Pasak Bumi Kalimantan Vol 7, No 2 (2024): JKPBK Desember 2024
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/j.kes.pasmi.kal.v7i2.9150

Abstract

Gangguan depresi diartikan sebagai gangguan emosi dan psikologis yang mengakibatkan kesedihan dan kehilangan minat terus-menerus. Sebesar 6,1% orang di Indonesia mengalami depresi, tetapi hanya 9% di antaranya yang mendapat pengobatan menurut hasil Riset Kesehatan Dasar tahun 2018. Terjadi penurunan neurotransmiter di otak pada orang yang mengalami gangguan depresi, yaitu pada serotonin, norepinefrin, dan dopamin. Mengekspos kulit ke sinar matahari adalah cara terbaik dalam pembentukan vitamin D. Sekitar 90% dari kebutuhan vitamin D manusia dipenuhi oleh paparan sinar matahari. Pembentukan vitamin D3 di kulit distimulasi oleh ultraviolet B. Vitamin D dalam bentuk 25(OH)D memiliki sifat fungsional dalam pembentukan hormon seks, baik pada perempuan (estrogen dan progesteron) maupun laki-laki (testosteron). Vitamin D juga termasuk dalam kelompok hormon steroid dan mampu melewati sawar darah otak yang berperan dalam regulasi dan modulasi sistem neurotransmitter. Reseptor vitamin D juga terdapat secara luas diseluruh otak dan merangsang pembentukan serotonin dan dopamin. Paparan sinar matahari yang adekuat dapat meningkatkan kadar vitamin D pada manusia. Peningkatan ini merangsang produksi neurotransmitter pada otak yang terlibat dalam gangguan depresi.
Co-Authors Abid Alfarizi, Muhammad Adam, Muhammad Fadlan Afifi, Azza Ayu Aminuddin, Muhammmad Andriansyah Andriansyah Annisa Muhyi Aslamiah Aslamiah Aswad, Fidya Mayastri Ayu Septiani, Ayu Azra, Dieni Bakhtiar, Rahmat Dahnilsyah, Dahnilsyah Endang Sawitri Evi Fitriany Fadilah, Syaiful Fikriah, Ika Guisandro, Johannes Hariyanto, Agustinus Darmadi Idris, Fagil Rananda Isjoni, Muhammad Yogi Ryantama Iskandar Muda Jesi Alexander Alim Joleha, Joleha Krispinus Duma Lubis, Nadhira Fahrani Mahmud Alpusari Maina, Annin Dya Meiliati Aminyoto muhammad dardi Nanda, A. Luthfiah Nandita, Meylaliazka Rahma Nataniel Tandirogang Neni Hermita Ningrum, Yuliana Kartika Noprianto, Dwi Nurkhalisa, Nina Nurtanio, Setyawan Nuryanto, Muhammad Khairul Pratiwi, Novita Eka Tyas Pualillin, Elvis Deddy Kurniawan Putri, Dwika Hanifah Putri, Nabiela Annisa Qahfi, Muhammad Andan Rachman, Syarifah Awwaliyyah Raharjo, Eko Nugroho Rasendriya , Fauzan Firjatullah Ronny Isnuwardana Rukaniya, Nurzilawati Ruslim, Samuel Kelvin Salsabila, Naila Cantika Sanjaya, Regina Anastasia Setyorini, Yulita Pundewi Sihombing, Syeba Sekarini Siti Khairiah, Siti Siti Khotimah Subagio, Kiki Jayapratama Sudarso, Sulistiawati Sunaryo, Muhammad Fitrah Ulyah, Rochimah Thul Waruwu, Riama Widjayanto, Arie Yadi Yasir Yudanti Riastiti Zetra Hainul Putra