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All Journal Media Kesehatan Masyarakat Indonesia Jurnal Penelitian Sains Jurnal Penelitian Kesehatan Suara Forikes As-syifaa Jurnal Farmasi Jurnal Ilmiah Manuntung Martabe : Jurnal Pengabdian Kepada Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Bidang Ilmu Kesehatan J-ADIMAS (Jurnal Pengabdian kepada Masyarakat) Jurnal Midpro JPKMI (Jurnal Pengabdian Kepada Masyarakat Indonesia) Lumbung Farmasi : Jurnal Ilmu Kefarmasian International Journal Of Science, Technology & Management (IJSTM) Journal Pharmasci (Journal of Pharmacy and Science) International Journal of Islamic and Complementary Medicine Indonesian Journal of Community Dedication in Health (IJCDH) Borneo Journal of Pharmacy Jurnal Teknologi dan Sains Modern (Medical Scientific Journal) MESINA Jurnal Kefarmasian Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Strada Jurnal Ilmiah Kesehatan (SJIK)
Septi Fandinata, Selly
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Journal : Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

 1 
PERBEDAAN KEPATUHAN MINUM OBAT PADA PASIEN YANG BARU TERDIAGNOSA DAN SUDAH LAMA TERDIAGNOSA PENYAKIT DIABETES MELITUS TIPE 2 Selly Septi Fandinata; Rizky Darmawan
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i1.310

Abstract

Diabetes mellitus is a chronic disease caused by insufficient insulin effectively. Compliance medication in patients diabetes mellitus is important to achieve treatment goals and effective to prevent complications in diabetes mellitus. The duration of suffering from DM is one of the factors that influences medication adherence. The purpose of this study is to compare the differences in adherence to taking medication between patients who have just been diagnosed with diabetes mellitus type II. Questionnaire instrument 4 indicators of compliance (right dose, right frequency, right interval, right time). Analysis statistical of the Mann-Whitney test. Total of 10 new patients and 20 old patients were diagnosed. The results study is patient to be compliant with right dose adherence 8 new patients (80%), 19 old patients (95%). Right frequency adherence 9 new patients (80%), 19 old patients (95%). Timely compliance 7 new patients (70%), 16 old patients (80%). Right interval adherence 4 new patients (40%), 13 old patients (65%). The results of data analysis showed p-value = 0.076> 0.05 there was no significant difference in adherence to taking medication between old patients and new patients with diabetes mellitus type II.
EFEKTIVITAS DAN KEAMANAN TERAPI NATRIUM DIKLOFENAK DAN PIROKSIKAM PADA PASIEN OSTEOARTHRITIS DI PUSKESMAS KOTA SURABAYA: PERBANDINGAN EFEKTIVITAS DAN KEAMANAN NATRIUM DIKLOFENAK DAN PIROKSIKAM PADA PASIEN OSTEOARTHRITIS Selly Septi Fandinata; Anita Purnamayanti; Primanitha Ria Utami
Jurnal Ilmiah Manuntung Vol 6 No 2 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v6i2.392

Abstract

Osteoarthritis (OA) is a disorder affecting the diarthrodial joints that support the skeletal system and the axial causing joint symptoms. The effectiveness of NSAID pain therapy in osteoarthritis often results in inadequate response and prolonged use can cause unexpected side effects. The therapy offered is diclofenac sodium and piroxicam. This research used the design of Quasy Experimental Design type Non Equivalent Control Group Design. The research was conducted at Puskesmas Tenggilis Surabaya. The outcomes measured as the intensity of pre and post treatment pain, Drug Side Effects on pre and post-treatment kidney function, and side effects on pre and post-treatment blood pressure. The study sampled 42 patients consisting of 20 patients (piroxicam group) and 22 patients (sodium diclofenac group). There was a significant difference with the intensity of the pain scale in both post groups (p= 0.001). There were no significant differences in average creatinine and BUN in the post treatment of pyroclacycam group and post treatment group sodium diclofenac (p = 0.772) and (p = 0.801). This study shows that the piroxicam group is more effective in reducing the pain scale than sodium diclofenac and both groups have not been shown to be safety in renal function (Creatinine and BUN)
POLIMORFISME CYP2C19*2 TERHADAP AGREGASI PLATELET DAN KEJADIAN KARDIOVASKULAR PADA PASIEN PENYAKIT JANTUNG KORONER Utami, Primanitha Ria; Rochmawati, Ike Dhiah; Fandinata, Selly Septi
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.405

Abstract

Coronary Heart Disease (CHD) is a cardiovascular disease that can caused by the presence of coronary artery plaque blockage. Clopidogrel is one of antiplatelet therapy in CHD patients. CYP2C19 *2 polymorphisms can reduce the effectiveness of clopidogrel active metabolites. This research was conducted at RSUD Sidoarjo East Java from November to December 2017continued monitoring of cardiovascular events to March 2018. The research method used is a method Polymerase Chain Reaction (PCR) and the Light Transmittance Aggregometry (LTA) method for platelet aggregation measurement. From 25 sample inclusion,there are wild type alleles (bp values ​​around 120 bp; 1 patient), homozygous alleles (bp values ​​around 169 bp; 18 patients) and allele heterozygotes (bp values ​​around 120bp, 169bp; 6 patients). The most common type of polymorphism is allele homozygotes. There is one patient hyperaggregation and cardiovascular events after being monitored for 3 months. Analysis relationship between CYP2C19*2 genetic polymorphisms with platelet aggregation and cardiovascular events, using the kruskal wallis test. The result is no significant relationship between CYP2C19*2 polymorphisms with platelet aggregation (p=0.512), as well as cardiovascular events did not make any difference which is also significant (p=0.426). The results of the association of platelet aggregation with cardiovascular events showed significant differences (p=0.027).
Co-Authors Agustiarini, Vitri Alfiana, Silvina Sita Amriani, Annisa Andik Isdianto Anita Purnamayanti Aristyawan, Andhika Dwi Aryanda Putra, Deddy Deddy Aryanda Putra Devi Ristian Octavia Djamilah Arifiyana Eziah Ika Lubada Eziah Ika Lubada Eziah Ika Lubada Fitriya, Fitriya Fitrya Fitrya Iin Ernawati Indra Puspitasari Indra Puspitasari, Indra Lubada, Eziah Ika Luthfiah, Annisa Mas Ulfa, Ninik Mercysca Suryandari Ninik Mas Ulfa Ninik Mas Ulfa Ninik Mas Ulfa Ninik Mas Ulfa Nisya, Norma Novita, Rennie Puspa Permatasari, Silfiana Nisa Primanitha Ria Utami Primanitha Ria Utami Primanitha Ria Utami Puji, Kinanti Ayu Puspa Novita, Rennie Putra, Deddy Aryanda Rizky Darmawan Rizky Darmawan Rizky Darmawan Rizky Darmawan Rizky Darmawan Rizky Darmawan Rizky Darmawan, Rizky Rochmawati, Ike Dhiah Silfiana Nisa Permatasari Suryandari, Mercysca Suryandari, Mercyska Ulfa, Ninik Mas Utami, Primanitha Ria Utari, Yunita Winda Wa Ode Sitti Zubaydah Yuni Hendrawati Zakiyah , Farah Afifatuz Zulfa, Ilil Maidatuz