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Journal : Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

IDENTIFIKASI KONTAMINAN TIMBAL DENGAN ELEKTRODA KERJA PASTA KARBON TERMODIFIKASI Esati, Ni Ketut; Cahyadi, Kadek Duwi
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.409

Abstract

This research identified lead (Pb) contaminants in vegetables. The measurement method used was anodic stripping voltammetry (ASV) with a working electrode of carbon paste modified acid-activated natural zeolite. The stages of the research were formulation of the working electrode, validation of the measurement method and measurement of lead levels in vegetables. The result showed that the optimum formulation of working electrode gave the highest measurement peak current. The optimum formulation with composition of graphite: liquid paraffin: acid activates zeolite is 100:35:10. This electrode was used for determination linear range concentration, limit of detection, percent recovery, and repeatability. The measurement of Pb using electrode by ASV method which gave valid results. It can be seen from a wide concentration range from 50-3000 ppb, a low detection limit of 55.28 ppb, good accuracy and precision. The application of this method is to measure Pb levels in vegetables, and the result is 1.43 mg/Kg.
EFEK EKSTRAK ETANOL AKAR CAKAR SETAN (Martynia annua L) TERHADAP AKTIVITAS SGPT DAN SGOT PADA TIKUS YANG DIINDUKSI CCl4 Jawa La, Elisabeth Oriana; Sawiji, Repining Tiyas; Esati, Ni Ketut
Jurnal Ilmiah Manuntung Vol 7 No 1 (2021): Jurnal Ilmiah Manuntung
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i1.414

Abstract

SGPT and SGOT activity from ethanol extract of cakar setan root (Martynia annua L) was investigated. Phytochemical screening was carried out on ethanol extract of cakar setan root (Martynia annua L). The animals were grouped into five groups which consist of 5 rats for each group. The normal/healthy group was only given food and drink the negative control group was given an aqueous suspension of 1 % CMC , the positif control group was given tablets Curcuma at a dose of 200 mg/Kg BB, the group ethanol extract Martynia annua L were each given extract at a dose of 200 mg/Kg BB and 400 mg/Kg BB. All groups were treated for 21 days orally. On day 22 were given injection of CCl4 1.0 mL/kg intraperitoneally except healthy group. The rats blood was taken and analyzed through eye orbitalis sinus AST and ALT activities. The result were statistically analyzed using One Way ANOVA test followed by LSD test. Phytochemical screening ethanolic extract of Martynia annua L root positively contains flavonoids, alkaloids, tannin, phenolic, and terpenoids. The result study that ethanol extract of cakar setan root (Martynia annua L) has hepatoprotective effect of being able to reduce activities of SGPT and SGOT in CCl4 induce white rats.