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All Journal Jurnal Biogenerasi Jurnal Riset Kefarmasian Indonesia JPK: Jurnal Proteksi Kesehatan Jurnal Pengabdian Masyarakat : Pemberdayaan, Inovasi dan Perubahan Jurnal Inkofar Jurnal Pengabdian Inovasi dan Teknologi Kepada Masyarakat Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Innovative: Journal Of Social Science Research JIKA SEGANTANG LADA : JURNAL PENGABDIAN KESEHATAN Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Putriani, Kony
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Journal : JPK: Jurnal Proteksi Kesehatan

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Utilization Of Secondary Metabolite Compounds from 96% Ethanol Extract of Pidada Leaves (Sonneratia caseolaris L) as an Antibacterial against Bacillus subtilis and Pseudomonas aeruginosa Bacteria Putriani, Kony; Serawaidi, Nadya Putri Aulya; Roswatidi, Eva; Andini, Febria
JURNAL PROTEKSI KESEHATAN Vol 13 No 1 (2024): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v13i1.877

Abstract

Infectious diseases are still a serious problem, and it is important to increase other sources of antimicrobial drugs from natural ingredients, one of which is the pidada plant. This research aims to determine the content of secondary metabolite compounds found in pidada leaves and determine the inhibitory power of pidada leaf extract against the bacteria Bacillus subtilis and Pseudomonas aeruginosa. This type of research is a real experimental laboratory with a maceration extraction method using 96% ethanol solvent and antibacterial testing using the well diffusion method with variations in extract concentration of 80%, 60%, 40% and 20%. The research results show that the extract contains flavonoids, phenolic compounds, saponins, tannins and steroids. The results of the antibacterial activity test showed that there was an inhibitory power at a concentration of 80%, namely Bacillus subtilis bacteria of 19.13 mm in the intermediate category and Pseudomonas aeruginosa bacteria of 17.18 mm in the intermediate category. The results showed that the ethanol extract of pidada leaves can inhibit the growth of Bacillus subtilis and Pseudomonas aeruginosa bacteria.
The Effectiveness of Avocado Leaf Ethanol Extract Ointment (Persea americana Mill.) on Incision Wound Healing in White Mice Sidoretno, Wahyu Margi; Putriani, Kony; Haikal, Fikri
JURNAL PROTEKSI KESEHATAN Vol 14 No 1 (2025): JPK: Jurnal Proteksi Kesehatan
Publisher : Poltekkes Kemenkes Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36929/jpk.v14i1.1048

Abstract

Avocado leaves (Persea americana Mill.) contain bioactive compounds that can aid in the wound healing process by reducing the number of neutrophils. This study aims to determine the effect of avocado leaf ethanol extract ointment on healing cuts on the back skin of white mice (Mus musculus ) strain Balbc. The study was based on a laboratory experimental design with a post-test control group. The research subjects included 5 male white mice for each treatment group. The treatment groups used extract concentrations in ointment preparations of K15%, K35%, and K45%, with a negative control (Vaseline) and a positive control (Gentamicin). The cuts were made by injuring the back skin along a length of 15 mm and a depth of 2 mm. Observations of wound length measurements were conducted from day 0 to day 14. The research data were analyzed statistically using One-Way ANOVA, followed by Duncan's Post Hoc test. The results showed that the most effective group was K45%, , which achieved complete wound healing within 12 days.
Co-Authors Andini, Febria Anggraini, Lovera Anita , Fenny Apriliani, Oksi Asiska Permata Dewi Faroliu, Goldha Fernenda, Larysa FIKRI HAIKAL Fricilia, Fitri Cindy Iballa, Brilian Dini Ma. Jannah , Mardiatul Komala sari, Komala Mardhiyani, Dini Nirnasari, Meily Nur Aisyah, Dewi Putri, Angelina Rahayu , Yessi Rahma Tri Cahyaningrum , Nanda Roswatidi, Eva Sativa , Oriza Serawaidi, Nadya Putri Aulya Shufyani, Fahma Sidoretno, Wahyu Margi Sugara, Bayu Utama, Vonny Kurnia Wahyu Ramadhan Wardaniati, Isna