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All Journal Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Indonesian Journal of Educational Studies COMPETITIVENESS JOURNAL SEIKO : Journal of Management & Business GOLDEN AGE: JURNAL PENDIDIKAN ANAK USIA DINI Jurnal Review Pendidikan dan Pengajaran (JRPP) Jurnal Bimbingan dan Konseling Borneo Jurnal Ilmiah Al-Mu'ashirah: Media Kajian Al-Qur'an dan Al-Hadits Multi Perspektif TEMATIK: Jurnal Pemikiran dan Penelitian Pendidikan Anak Usia Dini Chemistry Education Review Seminar Nasional Pengabdian Kepada Masyarakat Internet of Things and Artificial Intelligence Journal Indonesian Journal of Fundamental Sciences Journal of Artificial Intelligence and Digital Business UNESA Journal of Chemical Education ihyaulum ABDI DAYA: Jurnal Pengabdian dan Pemberdayaan Masyarakat Chemedu: Jurnal Ilmiah Pendidikan Kimia SMART: Jurnal Pengabdian Kepada Masyarakat
Muharram, Muharram
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Journal : Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia

 1 
Identifikasi dan Uji Bioaktivitas Senyawa Metabolit Sekunder dari Batang Bajakah Tampala (Spatholobus littoralis Hassk) Marsuki, Nur Annisa Fajri; M, Mohammad Wijaya; Muharram, Muharram
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 25, No 1 (2024): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v25i1.58556

Abstract

ABSTRAKPenelitian ini merupakan penelitian ekperimen yang bertujuan untuk mengidentifikasi senyawa metabolit sekunder yang terdapat dalam ekstrak etanol batang bajakah tampala (Spatholobus littoralis Hassk) dan untuk mengetahui mengetahui bioaktivitasnya dan komponen senyawa yang terdapat dalam ekstrak tersebut. Sampel penelitian diambil dari Provinsi Kalimantan Timur. Tahapan penelitian meliputi preparasi sampel, ekstraksi dengan maserasi, uji fitokimia, identifikasi senyawa dengan GC-MS dan uji bioaktivitas dengan metode BSLT. Hasil uji fitokimia menunjukkan adanya senyawa golongan flavonoid, saponin, fenolik, triterpenoid dan steroid. Adapun hasil identifikasi senyawa secara GC-MS menunjukkan keberadaan metabolit sekunder golongan fenolik dan steroid. Nilai LC50 pada uji bioaktivitas adalah 94,08 ppm atau 94,08 μg/mL. Nilai tersebut di atas menandakan bahwa ekstrak batang bajakah tampala memiliki potensi aktivitas biologis yang sangat tinggi sehingga berpotensi sebagai anti kanker dan anti bakteri.Kata Kunci: Bajakah Tampala, Spatholobus littoralis Hassk, dan SteroidABSTRACTThis study is an experimental study that aims to identify secondary metabolite compounds contained in ethanol extract of bajakah tampala stem (Spatholobus littoralis Hassk) and to determine its bioactivity and the components of the compounds contained in the extract. The research samples were taken from East Kalimantan Province. The research stages include sample preparation, extraction by maceration, phytochemical test, compound identification by GC-MS and bioactivity test by BSLT method. The results of phytochemical tests showed the presence of flavonoid, saponin, phenolic, triterpenoid and steroid compounds. The results of compound identification by GC-MS showed the presence of secondary metabolites of phenolic and steroid groups. The LC50 value in the bioactivity test was 94.08 ppm or 94.08 μg/mL. The value above indicates that bajakah tampala stem extract has a very high potential biological activity so that it has the potential as anti-cancer and anti-bacterial.Keywords: Bajakah Tampala, Spatholobus littoralis Hassk, and Steroids
Isolasi dan Identifikasi Senyawa Metabolit Sekunder Ekstrak Metanol Daun Pepaya (Carica papaya L.) Sasmita, Nur Mala; Muharram, Muharram; Maryono, Maryono
Chemica: Jurnal Ilmiah Kimia dan Pendidikan Kimia Vol 26, No 1 (2025): CHEMICA
Publisher : Jurusan Kimia FMIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/chemica.v26i1.71007

Abstract

ABSTRAKPenelitian ini bertujuan untuk mengetahui senyawa metbolit sekunder yang terdapat pada ekstrak methanol daun papaya (Carica papaya L.). Sampel Penelitian diambil dari Kelurahan Sudiang, Kecamatan Biringkanaya, Kota Makassar, Provinsi Sulawesi Selatan. Tahan penelitian ini meliputi preparasi sampel, ektraksi, fraksinasi, Pemurnian dan identifikasi. Hasil penelitian berupa isolat berwarna putih yang menunjukkan noda pada uji KLT multi eluen dengan perbandingan eluen yang digunakan yaitu n-heksana: kloroform 5:5, n-heksana: etil asetat (9:1) dan aseton: n-heksan (1:9). Titik leleh 122°C-124°C dan pada uji golongan isolat pada pereaksi Liberman-Buchard memberikan hasil positif senywa steroid berwarna hijau. Daerah serapan spektrum IR menunjukkan adanya beberapa gugus fungsi pada Bilangan gelombang, yakni O-H, C-H, C=C, CH2, CH3, dan C-O. Berdasarkan uji pereaksi serta data spektrum FTIR, kristal yang diperoleh merupakan golongan steroid yaitu senyawa β-sitosterol.Kata Kunci: Isolasi, Daun Pepaya, Metabolit Sekunder, β-sitosterol.ABSTRACTThis aims of this study to determine what secondary metabolite are found in papaya leaf metanol extract (Carica papaya L). The research sample was taken from Sudiang Village, Biringkanaya District, Makassar City, South Sulawesi Province. This research stage includes sample preparation, extraction, fractionation, purification and identification. The results of the research were white isolates which showed a single stain in the multi-eluent TLC test with the eluent ratios used being n-hexane: chloroform 5:5, n-hexane: ethyl acetate (9:1) and acetone: n-hexane (1: 9). The melting point is 122°C-124°C and the isolate group test using the Liberman-Buchard reagent gave positive results for green steroid compounds. The absorption area of the IR spectrum shows the presence of several functional groups at wave numbers, namely O-H, C-H, C=C, CH2, CH3, and C-O. Based on reagent tests and FTIR spectrum data, the crystals obtained belonged to the steroid group, namely the β-sitosterol compound.Keywords: Isolation, Papaya Leaves, Secondary Metabolites, β-sitosterol.  
Co-Authors A.A. Ketut Agung Cahyawan W Abdul Wahid Agussalim, Hastuti Alam, Muhammad Nur Alimin Alimin, Alimin Alkhair, Zia Aminuyati Appang Allo, Meli Banne Army Auliah Aulia, Nurul Army AULIYA RAHMAH, AULIYA Baharuddin Baharuddin BAKHRANI RAUF Basrah, Emmy Novita Dalle, Firda Anwar Damayanti, Risdah Ernawati Ernawati Fatwa, M Febrianti, Angriani Gani, Hamsu Abdul Hardianti Hardianti, Hardianti Hardin Hardin, Hardin Hasri Hasri Herlina Herlina I Nyoman Sila Idris, Siti Indriyati Ilyas, Nita Magfirah Imranah, Imranah Iwan Dini Jihadi, Ahmad Jusniar Jusniar, Jusniar Kustiah Sunarty, Kustiah Kusumaningrum, Retno Ayu M, Mohammad Wijaya M. Said Zainuddin Marsuki, Nur Annisa Fajri Martuty, Arie Maryono Maryono Mashuri, Arif Maulana Maulana, Maulana Muh. Yunus Muhaedah Rasyid Muhammad Agung Muhammad Anwar Muhammad Danial Muhammad Yunus Muin, Kasniar Mukhtar Galib Musi, Muhammad Akil Mutmainnah Mutmainnah Nafil, Zuhhad Netti Herawati Nur, Abdillah Mushawwir An Nurdin, Hikmah Nurlita pertiwi, Nurlita Pamungkas, Alfian Ramdani Ramdani Ramlawati Ramlawati Riska Riska Riswana, Riswana Sahrawati, Fiska Salnus, Subakir Salsabila, Unik Hanifah Sasmita, Nur Mala Septiani, Pranita Silambi`, Eda Sitti Faika Sudarmi Sudarmi Sugiarti Sugiarti Sulfiani, Ridha Suyanta Suyanta Syahrir, Muh. Taty Sulastry Titi, Titi Waleulu, Amalia Watiana, Watiana Yohandri Bow Yohanis, Yohanis Yunus, Ayu