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Journal : Jurnal Sains Materi Indonesia

Formulation and Characteristics of Sunscreen Cream based on Isolated Lignin from Oil Palm Empty Fruit Bunch (OPEFB) : Formulation and Characteristics of Sunscreen Cream Restu, Witta Kartika; Rusumayanti, Felli; Septiyanti, Melati; Muryanto; Aryana, Nurhani; Mawarni, Rista Siti; Meliana, Yenny; Sondari, Dewi; Fatriasari, Widya; Ogino, Chiaki
Jurnal Sains Materi Indonesia Vol. 26 No. 2 (2025): Jurnal Sains dan Materi Indonesia
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jsmi.2025.6199

Abstract

Lignin was recovered from black liquor during the biorefinery process and has prospective applications in pharmaceutical, cosmetic, and health care. Lignin, which has substantially smaller particles, was used as the active ingredient in the sunscreen cream formulation. The isolated lignin was examined for physicochemical parameters such as yield, purity, particle size, total phenol, and morphology. The obtained lignin was used in the preparation of sunscreen cream. The isolated lignin concentration in the cream varied between 0.1, 1, and 2 wt%. The sun protection factor (SPF) of the designed sunscreen creams was assessed, and antioxidant activity and stability were studied, which included pH, particle size, and appearance during the observation period. The formulated cream has an SPF of approximately 15, which is sufficient to protect human skin from the sun's UV radiation. Furthermore, the most significant antioxidant activity was found to be 68.94%. As a result, the developed sunscreen cream has the potential for further research because it is composed of natural active ingredients that are safe for humans and the environment.
Formulation and Characterization of Dewandaru Fruit Extract in Nanocarrier System Septiyanti, Melati; Nurfauziyah; Angelina, Marissa; Triana Dewi, Rizna; Fajriah, Sofa; Meliana, Yenny
Jurnal Sains Materi Indonesia Vol. 25 No. 2 (2024): Jurnal Sains dan Materi Indonesia
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jsmi.2024.3121

Abstract

Dewandaru (Eugenia uniflora L.) is a herbaceous plant that grows in tropical and subtropical regions. The fruit extract can prevent oxidative damage and cholinergic changes. It contributes to antihyperglycemic, antihyperlipidemic, and neuroprotective due to its antioxidants and antidepressant effect. It also possesses antibacterial and anti-inflammatory activity and potentially prevents cardiovascular disease and cancer. In this study, dewandaru fruit extract was formulated in the nanocarrier system (nanoemulsion and nanoencapsulation) to preserve product stability and improve product dispersibility and bioavailability. The nanoemulsion optimum formulation condition was obtained on dewandaru fruit extract concentration 10 wt%, oil/surfactant ratio 0.25, and homogenization speed 20.000 rpm, resulting in particle size of 46.4 ± 0.4 nm and polydispersity index 0.480 ± 0.015. The optimum nanoemulsion formulation was further processed to nanoencapsulation along with milling to produce finer particles. The nanoencapsulation milled for 120 minutes produced encapsulation powder with a size of 5.8 ± 3.340 μm. Accordingly, the nanocarrier technology for dewandaru fruit extract promoted a versatile medicinal preparation both in liquid and solid form. However, the size reduction by milling might disrupt the efficiency of the encapsulation release system. Without the proper coating, as orally administrated, the compound rapidly dissolved before it reached the targeted site.