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Fioni, Fioni
Universitas Prima Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary

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Journal : Jurnal Aisyah : Jurnal Ilmu Kesehatan

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The Potential of Tamarillo (Solanum betaceum) Peel as an Antioxidant by Radical Scavenging DPPH and Antiaging by Collagenase Inhibition Liena, Liena; Fioni, Fioni; Siregar, Lidya; Girsang, Ermi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 4: Desember 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i4.2504

Abstract

Background: The skin aging process, which is impacted by various variables, including genetics, advancing age, environmental conditions, and lifestyle choices, has emerged as a significant concern in skincare. Signs of skin aging, such as decreased firmness and elasticity and the appearance of fine lines and discoloration, have raised significant concerns. The link between free radicals and skin aging has been the subject of in-depth research, while collagenase activity has also been found to influence skin aging. The natural antiaging potential of herbal plants has been widely studied to overcome this problem, one of which is tamarillo (Solanum betaceum). Objectives: This study aimed to examine the antioxidant and antiaging properties of S. betaceum Peel Extract (SBPE). Method: Tamarillo peel was extracted using the maceration method. The antioxidant test was analyzed by trapping 2,2-diphenyl-1-picrylhydrazyl (DPPH), and the antiaging test was analyzed by collagenase inhibitory activity. Results: SBPE showed vigorous DPPH scavenging activity (IC50: 60.91 ± 0.36 ?g/mL), while SBPE also showed moderate collagenase inhibitory activity (IC50: 121.47 ± 2.32 ?g/mL). Conclusion: SBPE has high antioxidant activity and moderate antiaging activity.
The antioxidant and anti-elastase activities of tamarillo fruit extract (Solanum betaceum) Fioni, Fioni; Liena, Liena; Siregar, Lusyana; Girsang, Ermi
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 4: Desember 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i4.2508

Abstract

Skin aging is a complex process characterized by structural and functional loss of skin tissue. Aging is triggered by reactive oxidative stress (ROS), which activates enzymes involved in the aging process, such as elastase. Tamarillo is one of the natural plants that has various chemical compounds that have the potential to be antioxidants and anti-aging. The objective was to examine the antioxidant and antiaging activity of Tamarillo Fruit Extract (TFE). The H2O2 scavenging assay and anti-elastase assay were used. The result shows that TFE has a high antioxidant activity, as evaluated by H2O2 scavenging activity. The highest scavenging activity was found in a TFE concentration of 500 µg/mL (72.96%). Meanwhile, TFE shows its highest anti-elastase activity at a concentration of 66.67 µg/mL (32.33%). TFE's activity in both antioxidant and antiaging assays was concentration-dependent. The IC50 of the H2O2 assay was 278.20 µg/mL, and the IC50 of the anti-elastase assay was 110.67 µg/mL. Therefore, TFE shows its antioxidant and antiaging activities and has the potential to be used in further studies, both in vivo and clinical studies.
Co-Authors Arhani, Adli ARILYN, ERIKA JIMENA Aulia, Hilda Rafni Binarwan Halim Chen Wei Dewi Riastawaty Edy Fachrial Erwina Putri, Riri Fibrini, Dewi Florenly Florenly Florenly Florenly Florenly Florenly Girsang, Ermi Janice Janice Ji Junfeng Jiang Fan Johannes Bastira Ginting Khainir Akbar, Khainir Li Sha Li Wei Liana Liana Liena Liena Liena, Liena Lister, I Nyoman Ehrich Lubis, Asyrun Alkhairi Lumbantobing, Christina JRE Meutia, Rena Nardi, Leo Nasution, Ali Napiah Nasution, Chairul Radjab Pratama , Irza Haicha Rahimi, Armon Rahma Sari Razoki, Razoki Reh Malem br Karo Rizal Rizal Simatupang, Veronica Triwindari Sinurat, Jhon Patar Siregar, Lidya Siregar, Lusyana Tarigan, Antje Irmella WAHYU WIDOWATI Wienaldi, Wienaldi