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Journal : Jurnal Ilmiah Kesehatan Sandi Husada

Physical quality test of jamblang fruit ethanol extract antioxidant cream (syzygium cumini (l.) Skeels) Kadang, Yuniharce; Megawati, Megawati
Jurnal Ilmiah Kesehatan Sandi Husada Vol 13 No 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v13i2.1204

Abstract

Background: Antioxidants are compounds that can protect against oxidative stress caused by free radicals, both from inside the body (endogenous) and outside (exogenous). Many plants have antioxidant properties, including gambling (Syzygium cumini (L.) Skeels). This plant is known to have various bioactive components that can capture and neutralize free radicals; Jamblang fruit has antioxidant activity caused by the content of flavonoid compounds in it. These compounds can be utilized as topical preparations for skin care products. Objective: This study aims to determine the effect of ethanol extract concentration of jamblang fruit (Syzygium cumini (L.) Skeels) on the physical stability of the cream. Methods: This research is conducted in an experimental laboratory. Jamblang fruit extract was obtained using the maceration method using 96% ethanol. The extract was then formulated in the form of a m/a type cream preparation with concentration variations of 1% (FI), 2% (F2), and 3% (F3). The physical stability test of the cream includes viscosity, spread, adhesion, and pH value tests. The data is analyzed to determine the effect of adding extracts and the storage time on the physical stability of the cream. Results: The test showed that an increase in the concentration of ethanol extract from jamblang fruit led to a decrease in pH value, viscosity value, and adhesion and could increase dispersion. It was concluded that the variation in the concentration of ethanol extract from jamblang fruit influenced the physical properties of M/A cream. Conclusion: It can be concluded that the variation in the concentration of ethanol extract of jamblang fruit affects the physical properties of the oil cream in water (M/A). The effects caused include a decrease in pH value, a reduction in viscosity, a decrease in adhesion, and an increase in dispersion. These changes will ultimately affect the physical stability of the cream preparation.
The physical quality test formulation of ethyl acetate extract of kawista fruit peel (Limonia Acidissima L.) Ointment as an antibacterial against propionibacterium acnes Megawati, Megawati; Kadang, Yuniharce
Jurnal Ilmiah Kesehatan Sandi Husada Vol 13 No 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v13i2.1219

Abstract

Introduction: Using medicinal plants in Indonesia still needs to be optimized. Almost all parts of the Kawista plant have been traditionally used to treat various ailments such as antioxidants, antidiabetic, wound healing, and controlling uric acid levels. Existing research on Kawista fruit peel as an acne antibacterial includes studies on the ethyl acetate extract of Kawista fruit peel against Propionibacterium acnes, which falls into the moderate to strong category. In Indonesia, Kawista fruit is limited to the flesh and is used to make syrup and dodol (a traditional sweet). In contrast, the fruit's peel remains a waste product. Objective: This study aims to develop a formula for an ethyl acetate extract ointment of Kawista fruit peel (Limonia acidissima L.) as an antibacterial agent against Propionibacterium acnes with good physical quality. Methods: The fruit peel extract was obtained using the maceration method with 96% ethanol. The extract was then formulated into ointment preparations with concentration variations of 6.25% (F1), 12.50% (F2), and 25% (F3). The physical stability tests for the ointment included organoleptic parameters, homogeneity, spreadability, and pH value tests. The data were analyzed to determine the effect of the extract concentration and storage time on the ointment's physical stability. Result: The test results showed that the ointment formulation of Kawista fruit peel extract (Limonia acidissima L.) could be successfully formulated into an ointment form and met the required evaluation criteria, including organoleptic testing, homogeneity testing, pH testing, and spreadability testing. Conclusion: Based on the study, it can be concluded that the Kawista fruit peel extract ointment (Limonia acidissima L.) can be successfully formulated into an ointment and meets the required evaluation criteria, including organoleptic testing, homogeneity testing, pH testing, and spreadability testing. A skin irritation test is required to determine whether any irritation occurs after applying the ointment.