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All Journal Pharmasipha Reka Buana : Jurnal Ilmiah Teknik Sipil dan Teknik Kimia Sasambo Journal of Pharmacy
Julianti, Andi Ika
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Public Health

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Journal : Reka Buana : Jurnal Ilmiah Teknik Sipil dan Teknik Kimia

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Optimization of Phenolic and Flavonoid Extraction in Lavandula Angustifolia using Ultrasonic Assistance Extraction Ananda, Della; Julianti, Andi Ika; Akmal, Tubagus
Reka Buana : Jurnal Ilmiah Teknik Sipil dan Teknik Kimia Vol 10, No 1 (2025): EDISI MARET 2025
Publisher : Universitas Tribhuwana Tunggadewi Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/rekabuana.v10i1.6608

Abstract

Lavender contains active compounds such as flavonoids, tannins, coumarins, phytosterols, and minerals, which possess antioxidant properties and pharmacological potential. This study optimized the extraction process of lavender flowers to maximize bioactive phenolic and flavonoid yields. Ultrasonic-assisted extraction (UAE) was employed, and optimization was conducted using a Box-Behnken design in Design Expert 13.0.5.0 software. The influence of ethanol concentration, liquid-solid ratio (LSR), and extraction time on total phenolic content (TPC) and total flavonoid content (TFC) was evaluated. Results revealed that LSR significantly impacted the responses. Optimal conditions were determined as an LSR of 50 mL/g, extraction time of 26 minutes, and ethanol concentration of 26.12%. Validation under these conditions yielded a TPC of 152.26 mg GAE/g DE and a TFC of 68.59 mg QE/g DE, with percentage errors of −7.7% and 3.5%, respectively, demonstrating excellent agreement with the predicted values.
Co-Authors Akmal, Tubagus Aljan, Aljan Ananda, Della Febriyanti, Sapitri Lestari, Aulia Gustiani Mutiara, Pipyt Tanjung, Yenni Puspita