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Uji Efektivitas Sediaan Facial Wash Acne Gel Ekstrak Etanol Daun Nangka (Artocarpus heterophyllus Lamk.) Terhadap Bakteri Staphylococcus aureus Athaillah, Athaillah; Pritiwanti, Venni; Chandra, Putra; Affan Silalahi, Ali
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.787

Abstract

Background: Jackfruit leaves (Artocarpus heterophyllus Lamk.) contain antimicrobial compounds such as flavonoids, tannins, and saponins, which can damage bacterial cytoplasmic membranes and denature cellular proteins. This potential supports the development of a facial wash gel using jackfruit leaf extract as a natural antibacterial alternative. Objective: This study aimed to evaluate the effectiveness of a facial wash gel containing jackfruit leaf extract (Artocarpus heterophyllus Lamk.) in inhibiting the growth of Staphylococcus aureus ATCC® 25923. Methods: This experimental study included sample preparation, identification, extraction, phytochemical screening, and gel formulation evaluation (organoleptic test, homogeneity, spreadability, foam height, pH, irritation, and cycling test). Antibacterial activity was tested against S. aureus, with a positive control (Himalaya (Brand) Facial Wash) and a negative control (DMSO). Results: The extract yield was 11.26%, positively detecting flavonoids, saponins, tannins, steroids, and triterpenoids. The gel formulations (F1-F3) were semi-solid, dark green, and had a characteristic jackfruit leaf aroma, with a pH of 5–6. Homogeneity tests confirmed uniform consistency, with the highest foam height in F3 (3.7 cm) and optimal spreadability in F1-F2 (6 cm). No irritation was observed, and the gel remained stable in cycling tests. The antibacterial test showed the highest inhibition at 12% extract concentration (92.3%), while the formulated gel also effectively inhibited S. aureus growth. Conclusion: Jackfruit leaves can be successfully formulated into a stable and safe facial wash gel with effective antibacterial activity against Staphylococcus aureus.
Education on The Danger of Consuming Prescriptive Medicine for Health in Nogo Rejo Village, Galang District, Deli Serdang: Edukasi Bahaya Konsumsi Obat Setelan untuk Kesehatan di Desa Nogo Rejo Kec Galang Deli Serdang Rambe, Robiatun; Pangondian, Aswan; Husein, Saddam; Athaillah, Athaillah; Aini Khairunnisa, Nur
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): Edisi Juli 2025
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v5i2.1594

Abstract

A drug is defined as a collection of several drugs, usually in tablet or capsule form, repackaged in plastic and claimed to cure certain diseases. A drug is readily available in the community, yet there is no guarantee of quality and safety. This community service program aims to educate people about the dangers of using a drug. This activity was conducted using lectures and education methods regarding the health risks of using a drug. The target group was the community, women's groups (PKK), and officials in Nogo Rejo Village, Galang, Deli Serdang. The instruments used included PowerPoint presentations and questionnaires. This community service program began with basic outreach about a drug, and then assessed the community's knowledge of the drug through questionnaires. Pretest and posttest results indicated an increase in knowledge after the activity. The results showed that the community's knowledge in the pretest questionnaire was categorized as poor (0-59%), with an average score of 69%, with a score of sufficient (26%), and a score of good (5%). Meanwhile, the knowledge level in the post-test questionnaire fell into the good knowledge category (75-100%), with an average score of 28%, fair 49%, and sufficient 23%. The conclusion of this community service program is that there was an increase in the knowledge level of the community, PKK cadres, and village officials after being educated about the dangers of using prescription drugs. With this outreach and education, especially in Nogo Rejo Village, the community's knowledge and understanding of using prescription drugs will improve, allowing them to be more cautious and protective when consuming them.