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Santoso, Alexander Halim

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The Dermatological Effects of Vitamin D: Addressing Pore Size and Skin Roughness Tan, Sukmawati Tansil; Santoso, Alexander Halim; Jap, Ayleen Nathalie; Herdiman, Alicia; Averina, Friliesa; Gunaidi, Farell Christian
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.837

Vitamin D, or calciferol, is a fat-soluble vitamin produced endogenously when ultraviolet (UV) light triggers its synthesis in the skin. It also comes from food and supplements, existing as D2 (ergocalciferol) and D3 (cholecalciferol). Both forms convert into the active form, calcitriol, in the liver and kidneys, with D3 more effectively raising blood levels. Vitamin D supports bone health, regulates cellular functions, and offers anti-inflammatory, antioxidant, and neuroprotective benefits. It improves skin health by regulating oil production, soothing inflammation, promoting skin renewal, and strengthening the skin barrier. Deficiency (<20 ng/dL) weakens the skin barrier, causing dryness and roughness. The global prevalence of vitamin D deficiency is rising, with Southeast Asia, including Indonesia, experiencing rates between 35.1% and 91.7%. This study explores the relationship between vitamin D levels and skin health, focusing on pores and roughness in geriatric populations. This cross-sectional study analyzed 26 elderly, measuring vitamin D levels (Vitamin D 25-hydroxy (25(OH)D), skin pore size, and roughness (RGB analysis), with Spearman and partial correlation assessing relationships while controlling for age. Bivariate analysis showed a significant positive relationship between vitamin D levels and pore size (p = 0.03) and a strong, statistically significant relationship between pore size and skin roughness (p < 0.01). Vitamin D influences skin health, including pore size and texture. Monitoring vitamin D levels enables early intervention, improving skin appearance, reducing roughness, and preventing complications from vitamin D deficiency.

The Correlation Between Body Composition and Mini Nutritional Assessment in The Elderly: A Cross-Sectional Study Frisca, Frisca; Santoso, Alexander Halim; Setiawan, Fiona Valencia; Rayhan, Naufal; Sukianto, Louise Audrey
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.838

Aging leads to changes in body composition influenced by physical, psychological, and social factors. Understanding the relationship between fat distribution and nutritional status, particularly in older adults, is crucial for targeted interventions. This study examines the impact of body fat composition on nutritional assessment, particularly its influence on MNA scores in older adults. It aims to provide insights into how fat distribution and related metabolic changes affect nutritional status and inform targeted interventions for aging populations. The sample consisted of 31 elderly woman subjects selected through purposive sampling in a cross-sectional design from St. Francis of Assisi Catholic Church. Their nutritional status was determined using the MNA score, and the body composition measures were total body fat and skeletal muscle measured by the Omron Karada Scan HBF 375. SPSS analyzed statistical differences between body composition and MNA scores. This study found significant correlations between the Mini Nutritional Assessment scores and body composition parameters, including BMI (r = 0.473, p = 0.007), total subcutaneous fat (r = 0.468, p = 0.008), and visceral fat (r = 0.457, p = 0.010). Arm skeletal muscle showed a negative correlation (r = -0.486, p = 0.006). These results emphasize that fat composition is a critical determinant of nutritional status in the elderly. The study found a significant correlation between fat composition as a key determinant of nutritional status in the elderly, with significant correlations observed between MNA scores and various body fat parameters. Keywords: Body Composition, Elderly, Mini Nutritional Assessment

Exploring The Potential of Diabetes Panel and Albumin as Predictors on Urinary Incontinence in Elderly Soni, Yulfitra; Tambunan, Nicholas Albert; Santoso, Alexander Halim; Wijaya, Bryan Anna; Suros, Angel Sharon; Waltoni, Bobby Marshel Ancheloti
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.857

Urinary incontinence (UI) is a significant health issue among the elderly, affecting their quality of life. While its etiology is multifaceted, metabolic and nutritional markers such as diabetes panel parameters and albumin levels may play a role in its severity. However, the relationship between these biomarkers and UI remains underexplored. This study aims to investigate the association of diabetes panel components and albumin levels with the severity of UI in elderly individuals to identify potential predictors. A cross-sectional analytic study was conducted involving 93 elderly participants from Bina Bhakti Nursing Home. UI was assessed using the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF). Metabolic markers were analysed using validated methods, including fasting glucose, HbA1c, fasting insulin, HOMA-IR, and albumin. Data were statistically analyzed using Spearman’s Rho and multiple regression analyses to determine correlations and predictive relationships. Significant correlations were observed between HbA1c (r = -0.284, p = 0.006) and albumin (r = -0.259, p = 0.012) with UI severity. Multiple regression analysis confirmed that HbA1c and albumin are significant predictors of UI, with lower levels associated with increased UI severity. Diabetes panel parameters, particularly HbA1c and albumin levels, are valuable predictors of UI severity in elderly individuals. These findings emphasize the importance of metabolic and nutritional health monitoring in managing and mitigating UI symptoms. Future longitudinal studies and intervention trials are recommended to validate these findings and explore therapeutic implications.

The Correlation Between Blood Pressure, Basic Anthropometric Measurements, Hemoglobin, Hematocrit, Blood Sugar, and Uric Acid With Grip Strength in Elderly Women Lontoh, Susy Olivia; Ernawati, Ernawati; Santoso, Alexander Halim; Teguh, Stanislas Kotska Marvel Mayello; Lo, Geoffrey Christian; Setia, Nicholas
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.858

Grip strength is a key indicator of muscle function and health in elderly women, influencing mobility and independence. Factors such as blood pressure, body composition, and metabolic biomarkers influence grip strength. This study examines the relationship between blood pressure, anthropometric measurements, hemoglobin, hematocrit, blood sugar, and uric acid with grip strength. A cross-sectional study was conducted on 34 elderly women (mean age: 72.24 years) in the St. Asisi Elderly Community, Tebet. Blood pressure, anthropometric parameters, and venous blood samples were analyzed. Grip strength was assessed using the Camry Electronic Hand Dynamometer. Statistical analysis used the Spearman correlation test (p < 0.05). Age showed a significant negative correlation with right-hand (p = 0.023) and average grip strength (p = 0.026), indicating muscle decline with age. Other factors, including blood pressure, hemoglobin, hematocrit, blood sugar, and uric acid, had no significant correlations. Among anthropometric measures, calf circumference showed the strongest positive correlation with grip strength (p = 0.063). Age is the primary factor affecting grip strength in elderly women, with weak or no significant associations for other parameters. Strength training and neuromuscular conditioning may help mitigate age-related muscle decline and support functional independence.

Peningkatan Kesehatan Mental dengan Pemantauan Kadar Vitamin D pada Kelompok Lanjut Usia Biromo, Anastasia Ratnawati; Santoso, Alexander Halim; Tadjudin, Noer Saelan; Satyanegara, William Gilbert; Destra, Edwin; Gunaidi, Farell Christian; Herdiman, Alicia; Averina, Frilliesa
Jurnal Kesehatan Amanah Vol. 9 No. 1 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i1.890

Vitamin D is a micronutrient required by the body. Vitamin D has various functions, including its potential to prevent depression. There are studies suggesting that people with depression are at risk of vitamin D deficiency. This study discusses the correlation between vitamin D and depression. This is a cross-sectional study designed to investigate the relationship between vitamin D levels and depression in elderly (≥ 60 years) residing at Bina Bhakti Nursing Home. Participants who meet the criteria underwent measurement of vitamin D levels and assessment for depression using the Geriatric Depression Scale (GDS). Spearman correlation is used as the statistical analysis to evaluate the relationship between variables. 93 respondents met the criteria with average age of 74.19 years (61-97 years). 77 respondents were female (82.8%) and 16 respondents (17.2%) were male. The mean vitamin D level was 9.78 ng/ml (1.07-25.6ng/mL) and the mean GDS score was 4.51 (0-15). The results of the analysis showed a significant negative correlation between vitamin D levels and GDS scale (-0.287, p-value=0.005). Low vitamin D levels are associated with increased GDS scores, indicating that it is important for the elderly to fulfill their vitamin D needs as an preventive measure against depression

Co-Authors Abizar Rafi, Muhammad Adam Adhim, Laudza Al Aditya Pratama Aditya, Raden Seliwat Agung Aditya, Vincent Adjie, Eko Kristanto Kunta Agustina Akhmad, Fariz Azril Khaidar Alexandro, Cristian Alexin, Corry Calista Alifa, Tosya Putri Alifia, Khalisya Alifia, Tosya Putri Alkarni, Muhammad Dedy Alvianto, Fidelia Alwini, Muhammad Rifat Umar Amanda, Shelma Tria Amertha, Anak Agung Ngurah Putrayoga Amimah, Ranindita Maulya Ismah Andersan, Jonathan Andria Priyana Anggraeni, Natasha Anthony, Louis Aqila, Fitri Atzmardina, Zita Aurellya, Najwa Averina, Friliesa Averina, Frilliesa Aziel, Disya Gwyneth Bachri, Fiqi Afrizal Biromo, Anastasia Ratnawati Bryan Anna Wijaya Bustam, Steve Geraldo Cahyadi, Stanley Surya Cendi, Sylvia Charissa, Olivia Chian, Sung Christiana, Catherine Chua, Jimmy Daniel Goh Dava Pratama, Muhammad Kevin David Limanan Destra, Edwin Dewanto, Naomi Esthernita Fauzia Dewanto, Paulus Gegana Thery Dewi, Andriana Kumala Dewi, Fransiska Iriani Roesmala Dinali, Diana Drew, Clement Dwiana, Alya Dzakwan, Muhammad Fikri Edbert, Bruce Edbert, Juan Edwin Destra Emilda, Emilda Enike, Syilvia Cendy Enike, Sylvia Cendy Erdiana, Grace Ernawati Ernawati Ernawati Ernawati Evelyn Evelyn Evelyn EVELYN EVELYN Ezra, Pasuarja Jeranding Fajarivaldi, Kresna Bambang Febriana, Nafrisca Febriastuti, Abebi Felicia, Ivana Fiona Valencia Setiawan Fransisca I. R. Dewi Fransisco, Melkior Michael Frisca Frisca Frisca Gaofman, Brian Albert Ghina, Andini Goh, Daniel Gracienne Gracienne Gracienne Gracienne, Gracienne Gunaid, Farell Christian Gunaidi, Farell Christian Gunawan, Paskalis Andrew Hardjanto, Kevin Angga Hardjanto, Kevin Shen Angga Harsono, Axsel Hartono, Eric Hartono, Vincent Aditya Budi Haryanto, Ines Hekmatyar, Haritsyah Hendrianto, Rafindra Raja Hendrianto, Rifandra Rifqi Adi Herdiman, Alicia Herdiman, Julia Heri Yanto Putra Hidayat, Fadil Huang, Daniel Irawaty Hawari Ismi, Arni Istikanto, Ferdian Harum Jap, Ayleen Nathalie Jasmine, Angelia Jaya, I Made Satya Pramana Jeri Johan Johan Johan, Richver Framanto Kadang, Fidelis Samudra Kaminto, Eric Raditya Karjadidjaja, Idawati Karjadidjaja, Idawati Kartolo, Marendra Shinery Kartolo, Marenra Shinery Kasvana Kasvana Kasvana Kasvana, Kasvana Kelnia Mellenia Khoto, Anthon Eka Prayoga Kosasih, Robert Krezentian, Amelci Kristianto, Angeline Florencia Grace Kurniawan, Joshua Kurniawan, Junius Kusuma, Kanaya Fide Lo, Geoffrey Christian Lontoh, Susi Olivia Lontoh, Susy Olivia Lucius, Steven Hizkia Lumintang, Valentino Gilbert Mahendri, Ryan Dafano Putra Mahendri, Ryan Daffano Putra Mandalika, Astin Marcella, Agnes Marcellino, Marcellino Marendra Shinery Kartolo Martin, Alfianto Mashadi, Fladys Jashinta Massie, Andrew Christian Mayvians, Tizander Moniaga, Catharina Sagita Monika, Sesilia Natalie, Michelle Ruth Nathanael, Fernando Nathaniel, Fernandho Nathaniel, Fernando Nicholas Setia Nikita Noer Saelan Tadjudin Normala, Ajeng Permatasari, Nabila Jingga Peter Ian Limas Philo, Andrew Pranata, Catherine Christiana Pratama, Muhammad Kevin Dava Pratomo, Farhan Prayogo Khoto, Anthon Eka Purnomo, Yonathan Adi Putra, Feri Yanto Putra, Heri Yanto Putra, Muhammad Dzakwan Dwi Putri, Tiara Aulia R Dewi, Fransisca Iriani Rafi, Muhammad Adam Abizar Rafif, Akhtar Nawfal Raharjo, Anthony Jason Raharjo, Budiarjo Notonagoro Ramadhani, Kenzie Rafif Ranonto, Steve Vallery Rayhan , Naufal Rayhan, Naufal Riadi, Seravin Janet Riantyarni, Tinezia Allia Rosadi Putra, Rosadi Rumawas, Marcella E. Ruslim, Daniel Ruslim, Welly Hartono Ryan Dafano Putra Mahendri S, Donatila Mano Saerang, Stefanus Hnady Santoso, Frisca Sari, Triyana Sarijuwita, Alicia Sartono, Stefanny Satyanegara, William Gilbert Satyo, Timothy Satyo, Yovian Timothy Setia, Nicholas Setiawan, Fiona Valencia Shirly Gunawan Sidarta, Erick Sidharta, Erik Sim, Alfred Sutrisno Singh, Arwinder Sitorus, Ribka Anggelline Hariesti Sitorus, Ribkha Anggeline Hariesti Siufui Hendrawan Soebrata, Linginda Soeltanong, Dianova Soni, Yulfitra Stanislas Kotska Marvel Mayello Teguh Su, Ernawati Sugiarto, Hans Sugiharto, Sony Sukianto, Louise Audrey Suros, Angel Sharon Susy Olivia Lontoh Sutedja, Gina Triana Syachputri, Rifi Nathaznya Syarifah, Andhini Ghina Syarifah, Andini Ghina Tamaro, Anggita Tambunan, Nicholas Albert Tan, Nikita Tan, Sukmawati Tansil Tantoso, Lidya Teguh, Stanislas Kotska Marvel Mayello Tiranda, Wisasti Gladys Chantika Valdes, Angeline Florencia Waltoni, Bobby Marshel Ancheloti Warsito, Jonathan Hadi Widjaja, Yoanita Wijaya, Bryan Anna Wijaya, Christian Wijaya, Dean Ascha Wijaya, Dean Ascha Wijaya Wijayadi, Linda Julianti William Gilbert Satyanegara Wohangara, Victor Sepriyadi Yogie, Giovanno Sebastian Yohanes Firmansyah Yudhitiara, Novia Yunita, Fenny Zhalila, Zhillan

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