Article Per Year (5 Year)
p-Index From 2020 - 2025
1.835
P-Index
This Author published in this journals
All Journal Meditory : The Journal of Medical Laboratory Jurnal Analis Kesehatan INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY JPP Jurnal Kesehatan Poltekkes Palembang JMLS: Journal of Medical Laboratory and Science Current Biomedicine Jurnal Kesehatan Siliwangi JIMMI: Jurnal Ilmiah Mahasiswa Multidisiplin
Durachim, Adang
Unknown Affiliation
Religion Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 12 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Jurnal Kesehatan Siliwangi

 1 
PENGARUH VARIASI LAMA DAN CARA SIMPAN FRESH FROZEN PLASMA (FFP) YANG TELAH DICAIRKAN TERHADAP JUMLAH TROMBOSIT Arum, Nafilah; Durachim, Adang; Marliana, Nina; Novia, Ganjar
Jurnal Kesehatan Siliwangi Vol. 4 No. 3 (2024): JURNAL KESEHATAN SILIWANGI
Publisher : Politeknik Kesehatan Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Fresh Frozen Plasma (FFP) merupakan komponen darah. FFP dapat digunakan pada pasien yang telah menerima transfusi darah masif dan terus mengalami pendarahan setelah transfusi trombosit. FFP dalam keadaan cair harus segera ditransfusikan selambat-lambatnya 6 jam setelah pencairan. Tujuan penelitian untuk melihat pengaruh variasi lama dan cara simpan Fresh Frozen Plasma (FFP) yang telah dicairkan terhadap jumlah trombosit. Jenis penelitian yang digunakan adalah kuasi eksperimen. Hasil pemeriksaan trombosit pada labu darah Fresh Frozen Plasma (FFP) yang berasal dari Platelet Rich Plasma (PRP) diberi perlakuan pada lama dan cara simpan yang bervariasi setelah dicairkan. Penelitian ini dilakukan dengan design serial waktu yaitu pembacaan trombosit pada FFP yang telah dicairkan di 0 jam (segera), 4 jam, dan 6 jam. Kemudian pembacaan serial waktu dilakukan dalam dua perlakuan berbeda, dengan penyimpanan di refrigerator 2-8°C dan agitator 20-25°C. Hasil rata-rata jumlah trombosit segera setelah dicairkan 0 jam, 4 jam dan 6 jam pada refrigerator adalah 94x103/µL. Sedangkan rata-rata jumlah trombosit pada penyimpanan agitator setelah 4 jam adalah 68x103/µL dan 6 jam adalah 46x103/µL. Hasil di uji statistik pada penyimpanan refrigerator suhu 2- 8°C nilai Sig. 0.84 >0.05 tidak berbeda bermakna secara statistik. Sedangkan pada penyimpanan agitator suhu 20-25°C nilai Sig. 0.00 <0.05 yang berarti terdapat perbedaan bermakna secara statistik.
HUBUNGAN VIRAL LOAD TERHADAP NEUTROPHIL LYMPHOCYTE RATIO (NLR) DAN LIMFOSIT T CD4+ PADA ORANG DENGAN HIV/AIDS (ODHA) Suhartini, Anita; Marliana , Nina; Hayati, Eem; Durachim, Adang
Jurnal Kesehatan Siliwangi Vol. 4 No. 3 (2024): JURNAL KESEHATAN SILIWANGI
Publisher : Politeknik Kesehatan Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Human Immunodeficiency Virus (HIV) adalah virus infeksi yang menyerang sistem kekebalan tubuh, menjadikan tubuh rentan terhadap berbagai penyakit. Pemeriksaan viral load, yang mengukur kuantitas RNA dalam darah, digunakan untuk menentukan tingkat keberadaan virus HIV. RNA berperan selama proses replikasi virus, membentuk dasar pembentukan virus baru. Sebagai penanda peradangan untuk mendiagnosis HIV dan mengukur tingkat keparahan infeksi HIV dapat menggunakan Neutrophil Lymphocyte Ratio (NLR) sebagai marker berbagai penyakit. Cluster of Differentiation 4 (CD4) adalah penanda pada permukaan sel limfosit T yang menjadi tempat melekatnya virus HIV. Penelitian ini untuk mengetahui hubungan viral load terhadap Neutrophil Lymphocyte Ratio (NLR) dan Limfosit T CD4+ pada orang dengan HIV/AIDS (ODHA). Penelitian ini menggunakan metode deskriptif korelasi dengan metode survey dengan pendekatan cross sectional. Populasi yang diperiksa merupakan penderita penyakit HIV yang melakukan pemeriksaan Viral load, NLR dan Limfosit T CD4+. Sampel diperoleh dari 30 orang penderita penyakit HIV yang melakukan pemeriksaan Viral load, NLR dan Limfosit T CD4+. Data statistik yang di gunakan yaitu uji korelasi Spearman. Hasil penelitian pada pasien ODHA menunjukkan rata - rata viral load adalah 34.432, NLR 3,18, dan CD4+ 229,4. Dapat disimpulkan terdapat hubungan antara Viral load dengan NLR dan CD4 dengan tingkat signifikansi < 0,05.
PENGARUH PENYIMPANAN ARSIP BLOK PARAFIN TERHADAP KUALITAS PREPARAT JARINGAN Nurdianti, Dinda; Wiryanti, Wiwin; Durachim, Adang; Gustira Rahayu, Ira
Jurnal Kesehatan Siliwangi Vol. 5 No. 2 (2024): JURNAL KESEHATAN SILIWANGI
Publisher : Politeknik Kesehatan Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Paraffin block archive storage is the process of maintaining and managing used paraffin blocks. "A standardized paraffin block archive storage system will facilitate access for diagnostic purposes and help maintain the quality of the paraffin blocks over the long term. If the storage system is not standardized, it can cause several problems, such as delaying diagnostic services and reducing the quality of tissue preparations. Most paraffin blocks can be stored at temperatures of 20-27°C. Paraffin blocks should not be exposed to temperatures exceeding 27°C, as improper storage can cause the paraffin to soften and damage the tissue, reducing the quality of tissue preparations. This study aims to determine the effect of paraffin block archive storage on tissue preparation quality. The research samples used paraffin block archives stored in cabinets for 5 and 6 years, and paraffin block archives stored in plastic for 5 and 6 years. The quality of tissue preparations was assessed based on the clarity of the arrangement of bile duct cell walls, namely mucosa, lamina propria, muscularis and serosa microscopically and the color contrast of nuclei and cytoplasm using ImageJ software. The results of the study showed that there was no significant effect of paraffin block archive storage on tissue preparation quality. Further research needs to be conducted on the storage duration of paraffin block archives in wooden and plastic cabinets over a period of 10 years, as well as obtaining information related to the initial condition of the paraffin blocks, including color, texture, shape,and tissue authenticity.
PERBANDINGAN HASIL PEWARNAAN PREPARAT HISTOLOGI MENGGUNAKAN XYLOL DAN MINYAK JAGUNG YANG DIPANASKAN PADA PROSES DEPARAFINISASI Mufidah, Zahra; Wiryanti, Wiwin; Durachim, Adang; Rahmat, Mamat
Jurnal Kesehatan Siliwangi Vol. 5 No. 2 (2024): JURNAL KESEHATAN SILIWANGI
Publisher : Politeknik Kesehatan Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Deparaffinization removes residual paraffin from tissue, enabling optimal dye absorption in histological preparations. While xylol is commonly used, its high exposure risks necessitate exploring safer alternatives. The research compares the efficacy of corn oil 60°C to xylol as a deparaffinization agent. Heated corn oil is necessary to reduce viscosity and increase solubility. Corn oil can also be used as an environmentally friendly and cost-effective alternative. The research employed a descriptive approach, comparing staining results of kidney tissue preparations from control and experimental groups. Assessment criteria included color uniformity and contrast, determined by the difference in Optical Density values between nuclear and cytoplasmic staining. Due to non-normal data distribution and the comparison of two unpaired means, the Mann-Whitney U test was utilized for statistical analysis. The results obtained an Asymp sig value of 0.002 where the value is included <0.05 which explains that there is a significant different on the staining results of tissue preparations deparaffinized using xylol and corn oil 60°C with the percentage of staining results in the good category deparaffinized using corn oil only reached 26.67%. The results showed that there were differences in the staining results of kidney tissue preparations deparaffinized using xylol and 60°C corn oil so that 60°C corn oil has less effective to be an alternative deparaffinization agent to replace xylol.
Co-Authors Arum, Nafilah Fathiasari, Fariha Fitriani, Ishma Dwi Gustira Rahayu, Ira Hardi, Zon Hayati, Eem Juliastuti, Aditya Lamsudiansyah, Asrul Yudha Fadhiila Mamat Rahmat Marliana , Nina Mufidah, Zahra Nabila, Lazulpa Nina Marliana, Nina Novia, Ganjar Noviar, Ganjar Nurdianti, Dinda Nurhayati, Betty Riyani, Ani Solihat, Mohamad Firman Suhartini, Anita Tania, Monica Widiawati, Widi Wiryanti, Wiwin