M. Yulianto Listiawan
Departemen/ Staf Medik Fungsional Ilmu Kesehatan Kulit Dan Kelamin Fakultas Kedokteran Universitas Airlangga/Rumah Sakit Umum Daerah Dr. Soetomo Surabaya

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Journal : Journal of General-Procedural Dermatology

Dapsone hypersensitivity syndrome overlaps reversal reaction in leprosy patient Liuwan, Chesia Christiani; Denisa, Medhi; Listiawan, M Yulianto
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 3, No. 2
Publisher : UI Scholars Hub

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Background: Leprosy is a chronic granulomatous infectious disease that primarily involves the skin and peripheral nerve and is caused by Mycobacterium leprae. Clinical features may vary depending on the patient’s immune response. Reversal reaction due to increased immunity is common after treatment in patients with borderline leprosy. Dapsone hypersensitivity syndrome (DHS) is an adverse effect from dapsone therapy that may occur in 5-6 weeks to 6 months after initial treatment. Case Illustration: A 47-year-old female complained of a spreading red patches on the skin of her trunk and extremities for three weeks duration. She also felt itchiness and tight sensation of rash. She experienced fever, pain, and numb lesions. She was diagnosed with leprosy and already had her sixth Multi Drug Therapy-Multi Bacillary (MDT-MB) regimen. From physical examination, on thoracic, abdominal, and extremities regions, multiple erythematous macules with hypoesthesia, sharply marginated ranging from size 3 to 5 cm along with discrete erythematous papules were found. Bacteriology index was zero. Patient was diagnosed with borderline leprosy with reversal reaction. After treated with prednisone, the patches became better, but the rash was still progressive. The rash had gotten significantly better after dapsone therapy was discontinued. Discussion: Borderline leprosy is immunologically unstable and can be complicated by reversal reactions. Reversal reaction is due to increased immunity and usually occurs after MDT treatment. Conclusion: Reversal reaction got better with prednisone, while DHS was significantly improved after stopping dapsone therapy. Drug patch test should be conducted after the lesion resolves in order to establish DHS.
The management of seborrheic dermatitis 2020 Widaty, Sandra; Bramono, Kusmarinah; Listiawan, Muhammad Yulianto; Yosi, Ariyati; Miranda, Eliza; Rahmayunita, Githa; Brahmanti, Herwinda; Lim, Henry W
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 5, No. 1
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Background: Seborrheic dermatitis (SD) is a chronic relapsing dermatitis manifesting in the seborrheic area, affecting infants or adults. In Indonesia, the prevalence of SD is 0.99–5.8% of all dermatology cases from 2013 to 2015. SD has been known to be a prominent manifestation among HIV patients, but there is an increasing trend in the general population. Therefore, in 2017, the Indonesian Society for Dermatology and Venereology proposed a consensus for the management of SD in Indonesia based on the discussion from 12 dermatological centers. Concurrent with the development of new drugs, this study aims to evaluate and develop a guideline for the treatment of seborrheic dermatitis in Indonesia to update the previous guidelines in 2017. Methods: Systematic review was based on evidence-based methods, and scientific evidences were acquired through systematic search. Evidence analysis was in accordance with the level of evidence. The available evidences were evaluated, and conclusion was based on the grade of recommendation. Critical appraisal was conducted by experts in dermatology and venereology. Results: Severity of SD can be determined by using the Seborrheic Dermatitis Area Severity Index. The principle of scalp SD management is controlling the scalp condition in a cost-effective manner to make patients comfortable. The recommendations for treatment of adult SD are topical agents, such as antifungals, nonsteroidal anti-inflammatory agents with antifungal properties, corticosteroids, and calcineurin inhibitors. Conclusion: We have updated and added newer agents for the treatment of SD. The approach is divided into scalp or nonscalp and also adult or infantile SD.
Contribution to hair and skin science in Indonesia through a research grant program Verschoore, Michele; setiawan, rhadeya; Listiawan, Muhammad Yulianto; Nurtami, Nurtami; Moreau de Montcheuil, Eloïse
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 8, No. 1
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To foster scientific advances in basic and clinical research projects, a philanthropic "hair & skin research grant" program was launched in 2021 through a partnership between University of Indonesia, Perdoski, and L’Oreal Research and Innovation. The aim of the program is to empower Indonesian scientists to generate research data on general skin and hair issues that affect the Indonesian population. We have grouped the eight grant projects awarded between 2021 and 2022 into five main themes: skin type characterization; skin microbiota; botanical extracts; photoaging therapies; and hair loss. The various studies are evaluating potential therapies for acne, skin aging, photoaging and male androgenetic hair loss (alopecia). The data will be useful for the development of guidelines for hair and skin care practices to raise awareness and educate the general public of Indonesia on the importance of skin and hair health.
Co-Authors Ade Fernandes Afif Hidayati Afif Nurul Hidayati Afif Nurul Hidayati, Afif Nurul Agnes Sri Siswati Alpha Fardah Athiyyah Amanda Gracia Manuputty Anak Agung Gede Sugianthara Anang Endaryanto Anggaraeni, Sylvia Anggraen, Sylvia Anggraeni, Sylvia Anum, Qaira Ardhiah Iswanda Putri Arifin Saiboo, Alvian Arisia Fadila Arisia Fadila Ariyati Yosi Astindari Astindari Astindari Astindari Astindari Astindari Astindari, Astindari Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra Bagus Haryo Kusumaputra, Bagus Haryo Bernadya Yogatri Anjuwita Bintanjoyo, Lunardi Brama Rachmantyo Brigita Ika Rosdiana Budi Prasetyo Budi Utomo Budi Utomo Budi Utomo Budiono Budiono Budiono Budiono Chesia Christiani Liuwan Chesia Christiani Liuwan Christina Avanti Christina Avanti Cindy Fransisca, Cindy CITA ROSITA S. PRAKOESWA Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Denisa, Medhi Densy Violina Harnanti Desiana Widityaning Sari Dhelya Widasmara Dhyah Aksarani Handamari Dhyah Aksarani Handamari Diah Mira Indramaya Dian Pertiwi Habibie Diana Kartika Sari DINAR ADRIATY Dominicus Husada Dwi Murtiastutik Dyah Ayu Pitasari Eliza Miranda Ellenita Soebakti Endang Wahyu Fitriani Erwin Astha Triyono Esti Hendradi Eva Lydiawati Evy Ervianti Fadila, Arisia Fajrin, Farah Meriana Farah Meriana Fajrin Farhat Surya Ningrat Fifa Argentina Flora Ramona Sigit Prakoeswa Geani, Silvani Githa Rahmayunita Hamidah Luthfidyaningrum Hardyanto Soebono Hari Basuki Notobroto Harningtyas, Citra Dwi Hartanto, Felix Henry Wan-Peng Lim Herwinda Brahmanti Indah Purnamasari Indah Purnamasari Indramaya, Diah Indraswari, Anindia INDROPO AGUSNI Ingrid Suryanti Suryono Irmadita Citrashanty Irmadita Citrashanty Irmadita Citrashanty Irmadita Citrashanty Irmadita Citrashanty Irmadita Citrashanty, Irmadita Iskandar Zulkarnain Iskandar Zulkarnain ISWAHYUDI ISWAHYUDI Jayawarsa, A.A. Ketut Kartika Paramita Kartini Hasballah Kurniati Kurniati Kurniati Kurniati Kurniati Kurniati Kusmarinah Bramono Lim, Henry W Linda Astari, Linda Lisa Aditama, Lisa Liuwan, Chesia Christiani Lubis, Ramona Sari Luh Made Mas Rusyati Lunni Gayatri Lunni Gayatri, Lunni Lydiawati, Eva Made Putri Hendaria Mamuaja, Enricco Hendra Mappamasing, Hasnikmah Maria Ulfa Sheilaadji Marina Rimadhani Maya Wardiana Maylita Sari Maylita Sari Maylita Sari Maylita Sari Maylita Sari, Maylita Medhi Denisa Medhi Denisa Alinda, Medhi Denisa Meita Ardini Pratamasari Meita Ardini Pratamasari, Meita Ardini Menul Ayu Umborowati, Menul Ayu Miranda, Eliza Moreau de Montcheuil, Eloïse Muchtar, Vitayani Mulianto, Nur Rachmat Netty Sukmawati, Netty Novianti Rizky Reza Nurtami Nurtami, Nurtami Pepy D. Endraswari Pepy Dwi Endraswari, Pepy Dwi Prakoeswa, Cita Rosita Pramitha, Riezky Januar Pratiwi, Karina Dyahtantri Priangga Adi Wiratama Putri Halla Shavira Putri Hendria Wardhani R.A. Astrid Putri Wandhita Rahmadewi Rahmadewi Rahmadewi Rahmadewi Ratana, Heng RATNA WAHYUNI Rebekah Setiabudi, Rebekah Regitta Indira Regitta Indira Agusni Renata Mayangsari Renni Yuniati Retha Retha Ridha Ramadina Widiatma Rinasari, Umi Riyana Noor Oktaviyanti Rozita Maharani, Dinda Rubianti, Marissa Astari Sandra Widaty Sandra Widaty Santi Martini Santoso, Rachmat Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Sawitri Septiana Widyantari setiawan, rhadeya SHINZO IZUMI Silvani Geani Sirithida, Chukmol Sofia Sofia, Sofia Sri L. Menaldi Tanojo, Natalia Tengku Riza Zarzani N Tjokorde Istri Nindya Vaniary Trisniartami Setyaningrum Vannda, Sou Veithzal Rivai Zainal Verschoore, Michele Vidyani Adiningtyas Vortey, Hak Wahyu Lestari Widyantari, Septiana Willy Sandhika Winnugroho Wiratman, Manfaluthy Hakim, Tiara Aninditha, Aru W. Sudoyo, Joedo Prihartono Yoana Fransiska Wahyuning Christi Yohanes Aditya Adhi Satria Yosi, Ariyati Yuindartanto, Andre Yuli Wahyu Rahmawati