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Indriatmoko, Dimas Danang
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Journal : Jurnal Kartika Kimia

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Karakterisasi Gelatin Tulang Ikan Tongkol (Euthynnus affinis) dengan Penghidrolisat Asam Asetat Al-Faroji, Didin Syahrudin; Sabrina, Mariam; Sumiardi, Ade; Suryani, Nani; Indriatmoko, Dimas Danang
Jurnal Kartika Kimia Vol 6 No 1 (2023): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v6i1.206

Abstract

Gelatin merupakan salah satu jenis protein konversi yang diperoleh melalui proses hidrolisis kolagen dari kulit, tulang dan jaringan serat putih (white fibrous) hewan. Bahan baku utama yang digunakan dalam produksi gelatin adalah tulang sapi, kulit sapi, dan kulit babi. Bagian tulang ikan tongkol (Euthynnus affinis) dapat dimanfaatkan sebagai salah satu sumber gelatin. Penelitian ini bertujuan mengisolasi gelatin dari tulang ikan E. affinis menggunakan asam asetat sebagai penghidrolisat serta mengkarakterisasi kandungan asam amino menggunakan Kromatografi Cair Kinerja Tinggi. Gelatin tulang E. affinis berwarna kuning kecoklatan dengan rendemen sebesar 12,2%, kadar air 10%, kadar abu 1,03%, pH 4,33, dan viskositas 3,44 cP serta kekuatan sebesar 67,54 g.bloom. Gelatin tulang E. affinis mengandung 77,7 asam amino yang terdiri dari prolin 8,76 %, glisin 23,5 % dan triptofan 0,01 % yang merupakan asam amino khas kolagen.
Perbandingan Aktivitas Antioksidan dan Antikolesterol serta Kandungan Fenolik dan Flavonoid dari Ekstrak Khaya (Khaya anthotheca) Suryani, Nani; Komalasari, Komalasari; Sulistriyani, Sulistriyani; Rudiana, Tarso; Ernawati, Eneng Elda; Indriatmoko, Dimas Danang; Jayantie, Dhyneu Dwi; Khaerunnisa, Arini
Jurnal Kartika Kimia Vol 8 No 1 (2025): Jurnal Kartika Kimia
Publisher : Department of Chemistry, Faculty of Sciences and Informatics, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkk.v8i1.906

Abstract

Hypercholesterolemia is closely related to cardiovascular disease, which can increase the risk of atherosclerosis. Oxidative stress is related to the development of atherosclerosis because it is related to cellular responses triggered by an imbalance between oxidants and reductants in various layers of blood vessel tissue. K. anthotheca has pharmacological benefits as an antileishmaniasis and antimalarial. The purpose of this study was to determine the antioxidant and anticholesterol activity of K. anthotheca bark based on the type of solvent and to determine the phenolic and flavonoid content of the most active extract. The results indicated that ethyl acetate extract had the best antioxidant activity compared to n-hexane and ethanol extracts, with an IC50 value of 47.82 ppm, followed by ethanol extract at 48.46 ppm and n-hexane extract at 101.89. The value of antioxidant activity is directly proportional to the anticholesterol activity, where the ethyl acetate extract has an EC50 value of 20.42 ppm, the ethanol extract 445.58 ppm, and the n-hexane extract 1,073 ppm. The ethyl acetate extract has a phenolic content of 229.765 mgGAE/g extract and a flavonoid content of 7.63 mgQE/g.
Co-Authors Ade Sumiardi Agus Setiawan Al-Faroji, Didin Syahrudin Arini Khaerunnisa Cory Novi Effendi, Erwin Ernawati, Eneng Elda Jayantie, Dhyneu Dwi Junaedi, Candra Kartika, Eka Yulli Komalasari Komalasari Nani Suryani Nurhayati, Ghina Siti Sabrina, Mariam Siswanti, Dwi Marwati Juli Stiani, Sofi Nurmay Sulistriyani, Sulistriyani Swastika Oktavia Tarso Rudiana, Tarso Yusransyah, Yusransyah