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All Journal MEDISAINS Journal of Community Services and Engagement Abdimas Umtas : Jurnal Pengabdian kepada Masyarakat Jurnal Ilmiah Cendekia Eksakta PREPOTIF : Jurnal Kesehatan Masyarakat Borneo Journal Of Pharmascientech Community Empowerment Jurnal Farmasi Prosiding University Research Colloquium Jurnal Farmasi Indonesia Journal of Community Services and Engagement: Voice of Community (VOC)
Wijayatri, Ratna
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Journal : Jurnal Farmasi Indonesia

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Formulasi Dan Optimasi Sediaan Salep Luka Akut Berbasis Daun Wungu Graptophyllum Pictum L. Griff Dan Madu Klanceng Oktaviyani, Tiwi; Wijayatri, Ratna; Wahyuningtyas, Eka Sakti; Handayani, Estrin; Kamal, Sodiq
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 17 No. 2 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i2.409

Abstract

Abstract: Acute wounds require quick and appropriate treatment to prevent complications such as infection and scar tissue formation. This study aims to develop and optimize an ointment formula based on Graptophyllum pictum L. Griff wungu leaf extract and klanceng honey, which is intended to prepare for the healing of acute wounds. Graptophyllum pictum L Griff leaves are known to have anti-inflammatory and antimicrobial properties, while klanceng honey is famous for its ability to accelerate tissue regeneration. The research process included the determination of Graptophyllum pictum L Griff leaves to ensure the authenticity of the ingredients, extraction using the maceration method with 96% ethanol and the manufacture of Graptophyllum pictum L Griff leaves ointment with concentrations of F1 10%, F2 7.5% and F3 5%. Evaluation of physical properties through a series of preparation tests to assess organoleptic, homogeneity, pH, dispersibility, adhesion, and stability. The optimization of the ointment preparation of the combination of Graptophyllum pictum L Griff leaves and klanceng honey showed that the ointment met all quality criteria as an ointment preparation intended for acute wounds, the preparation also had excellent stability. This research is expected to be the basis for the development of natural products for the treatment of acute wounds that are more effective, and safe to use.
Co-Authors Aisyah, Shofi Afra Asmaul Husna Aulia, Salshabilla Ramadhisa Ayu Shabrina Azzahra, Ni'matun Nada Benita, Intan Ayu Cahyanda, Annisa Shinta Capritasari, Rafiastiana Eka Sakti Wahyuningtyas Estrin Handayani Farida Farida Geovani, Cagiva Hafiz, Nur Heni Lutfiyati, Heni Hidayat, Imron Wahyu Isnanti, Hervina Khasanan, Putri Uswatun Lestari, Lufandati Narizki, Muhammad Jidan Ningrum, Yessika Ardian Nofariyanto, Haris Nurchollifah, Yeny Octavianto, Putra Winly Oktaviyani, Tiwi Pradani, Missya Putri Kurnia Putri, Meilisa Sabrien, Diva Adela Sakti Wahyuningtyas, Eka Septiana, Vanny Eka Setyo Budi Santoso Sodiq Kamal Sri Hananto Ponco Nugroho Wahyu Hidayat, Imron