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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)
Nasution, Melati Silvanni
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : The Journal of Society Medicine (JSOCMED)

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Lipid Profile in Confirmed Covid-19 Patients with Type 2 Diabetes Mellitus At Haji Adam Malik General Hospital Medan from March 2020 to December 2021 Sitepu, Annisa Nidya Rahmatika; Lindarto, Dharma; Nasution, Melati Silvanni
Journal of Society Medicine Vol. 2 No. 3 (2023): March
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i3.37

Abstract

Introduction: Diabetes can cause secondary hyperlipidemia. In COVID-19, dyslipidemia is thought to be the result of biological and pathological processes triggered by SARS-CoV-2. Altered lipid profiles have been reported since the beginning of the COVID-19 pandemic, where the alteration of lipid profile and the severity of SARS-CoV-2 infection were positively correlated. This study aims to analyze the lipid profile in confirmed COVID-19 patients with T2DM at H. Adam Malik General Hospital Medan. Method: This was a descriptive study with a cross-sectional design using a total sampling technique by collecting secondary data on inpatients with confirmed COVID-19 with T2DM  at H. Adam Malik General Hospital from 2020 to 2021 which was then analyzed using the SPSS version 25 application. Results: Of the 372 subjects, the most common sex was male (57.3%), 193 people had a BMI of 18.5 - 24.9kg/m2 (51.9%), the mean overall age was 57.5 ± 10.4 years, and the median length of stay was 8 days. The most common comorbid was hypertension (n=189, 50.8%), 176 people had severe COVID-19 (47.3%), and 225 patients were discharged (60.5%). Based on laboratory data, 327 people had dyslipidemia (87.9%), 31 people had mild acute liver impairments (8.3%), the average of HbA1c was 9.0±2.5%, the average fasting blood glucose was  221.7±122.2 mg/L, the average 2 hours post-prandial blood glucose was 261.7±125.8 mg/L, an average of total cholesterol was 151.2±52.2 mg/L, an average of triglycerides was 147.5±99.1 mg/L, an average of HDL was 33.1±14.6 mg/L, an average of LDL was 97.4±44.5 mg/L, the median of ALT was 25 μ/L, and an average of AST was 30.45±27.42 μ/L. Conclusion: Total cholesterol, triglyceride, and LDL were lower in T2DM patients with a critical illness of COVID-19 and patients who died.
Determinants of Frailty Status in Elderly Patients with Permanent Pacemakers at Adam Malik Hospital, Medan Irawan, Raja Alfian; Ariestine, Dina Aprilia; Lubis, Anggia Chairuddin; Sungkar, Taufik; Nasution, Melati Silvanni
Journal of Society Medicine Vol. 4 No. 8 (2025): August
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i8.229

Abstract

Introduction: Frailty is highly prevalent among elderly patients following permanent pacemaker implantation, with rates exceeding 70%. The Comprehensive Geriatric Assessment (CGA) evaluates frailty through domains such as nutrition (Mini Nutritional Assessment, MNA), comorbidities (Charlson Comorbidity Index, CCI), functional status (Barthel Index), cognition (Mini Mental State Examination, MMSE), mood (Geriatric Depression Scale, GDS), quality of life, polypharmacy, and pacemaker implantation duration, alongside sociodemographic factors like age and sex. Identifying factors influencing frailty is essential for optimizing outcomes and quality of life in this population. Methods: This cross-sectional study included patients aged ≥60 years with permanent pacemakers attending the Arrhythmia Clinic at Adam Malik Hospital, Medan, from October to December 2024. Frailty was assessed using the CGA. Bivariate analyses employed Fisher’s exact test and chi-square tests to evaluate associations between frailty scores and variables including MNA, CCI, Barthel Index, MMSE, GDS, quality of life, polypharmacy, implantation duration, age, and sex. Multivariate logistic regression was used to identify significant predictors of frailty. Results: Of 62 participants, 62.9% were aged 60–74 years. Bivariate analysis revealed that 58.1% of malnourished patients (per MNA) were frail (p<0.008), and 94.1% of those on polypharmacy regimens were frail (p<0.001). Multivariate analysis identified polypharmacy as the only significant predictor of frailty (OR 14.0; 95% CI 2.186–89.675). Conclusion: Nutritional status and polypharmacy are associated with frailty in elderly pacemaker patients, with polypharmacy showing a significant independent effect. Targeted interventions addressing polypharmacy may improve frailty outcomes in this population.
Co-Authors Amalia Puspita Dewi Ariestine, Dina Aprilia Brama Ihsan Sazli dharma Lindarto, dharma Dian Anindita Lubis Hastopraja, Ressy Irawan, Raja Alfian Lubis, Anggia Chairuddin Lubis, Dian Anindita Lubis, Heny Syahrini Lydia, Wika Mardianto Muhammad Aron Pase Nasution, Ali Nafiah Nasution, M. Arif Habibi Pase, Muhammad Aron Pohan, Hafiza Humayra Prabisma Santi Syafril Siregar, Anisafitri Sitepu, Annisa Nidya Rahmatika Taufik Sungkar, Taufik