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Journal : Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam

SINTESIS KALKON TURUNAN PIRIDIN DARI ASETILTIOPEN DAN PIRIDINKARBALDEHID SERTA UJI ANTIOKSIDAN MENGGUNAKAN METODE DPPH Indah Fitria Ningsih; Nur Balatif; Jasril '
Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam Vol 1, No 2 (2014): Wisuda Oktober 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam

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Abstract

The compounds of condensation reaction have been synthesized using microwave irradiation with a base catalyst and their antioxidant activity were evaluated. One of the result of synthesized compounds was (4-hydroxy-2,6-di(pyridin-3-yl)-4-(thiophen-2-yl) cyclohexane-1,3-diyl) bis (thiophen-2-ylmethanone) (IF). The structure of the synthesizedproduct has been elucidated using IR, 1H-NMR, 13 1 C-NMR, mass-spectroscopic data and elemental analysis. The final product was screened for its antioxidant activity. The compound exhibited low DPPH (2,2’-diphenyl-1-picrylhydrazyl) scavenging activity which gave IC50 value > 500 ppm.
PERBANDINGAN ISOLASI MINYAK ATSIRI DARI BUNGA KENANGA (Cananga odorata (Lam.) Hook.f & Thoms) CARA KONVENSIONAL DAN MICROWAVE SERTA UJI AKTIVITAS ANTIBAKTERI DAN ANTIOKSIDAN Fela Tri Anggia; Yuharmen '; Nur Balatif
Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam Vol 1, No 2 (2014): Wisuda Oktober 2014
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cananga odorata (Lam.) Hook.f & Thoms plants were one of essential oil sources wich has an antibacterial and antioxidant activity. In the research, isolation of essential oil from Cananga odorata (Lam.) Hook.f & Thoms was carried out with traditional hydrodistillation method and microwave method. The optimalcondition in the traditional method was 4 hours, while the optimal condition in the microwave method were 100o C, 40 minutes and 600 W. Isolation of the essential oil from Cananga odorata (Lam.) Hook.f & Thoms using microwave method produced higher yield (1,08%) compared to the traditional method (0,62%). The essential oil from Cananga odorata (Lam.) Hook.f & Thoms was indentified by GC-MS and resulted 35 compounds for traditional method and 53 compounds formicrowave method. Antibacterial activity assay showed equal result for both methods, that the Gram-negative bacteria (Salmonella enteritidis, Staphylococcus aureus) were more active in inhibiting the growth of bacteria compared to Grampositivebacteria (Escherichia coli, Bacillus subtilis). The antioxidant activity assay of the essential oil from Cananga odorata in the microwave method (884,31 µg/mL) was better than that of the traditional method (883,78 µg/mL).