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All Journal ACTA VETERINARIA INDONESIANA Jurnal Kedokteran Hewan Jurnal Medika Veterinaria
M Nur Salim
Fakultas Kedokteran Hewan Universitas Syiah Kuala.
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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Journal : Jurnal Medika Veterinaria

 1 
39. Efficacy of Jatropha cream (Jatropha curcas L.) on maturation phase of cutaneus healing process in Mice (Mus Musculus) Abdul Harris; Cut Mentari Fatihah Amran; M. Nur Salim; Ummu Balqis; T. Armansyah; T. Fadrial Karmil; Ginta Riady
Jurnal Medika Veterinaria Vol 13, No 2 (2019): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v13i2.15900

Abstract

This study aims to determine the efficacy of jatropha curcas L. cream in the maturation phase of healing of mice leather injuries. This study used nine rats with 3 treatments, ie treatment group I smeared cream base (P1), treatment group II smeared 0.1% sulfadiazine cream (P2) and treatment group III smeared jatropha curcas 10% (P3). The result of ANAVA test of treatment I, treatment II and treatment III had significant effect (P 0,05) on fibroblast cells but each treatment group on collagen density level showed significant effect (P 0.01). Duncan test results on fibroblasts, P3 was significantly different (P 0.05) with P2 and P3, whereas the results on P3 collagen density were significantly different (P 0.01) with P2 and P1. The conclusion that 10% jatropha gum cream for 10 days can decrease the number of fibroblast cells and increase the amount of collagen thus accelerate the process of maturation phase of healing of mice leather injuries.
9. The Effectiviteness of Jatropha salve (Jatropha curcas L) in Inflammatory Phase of cutaneous wound healing in Mice (Mus musculus) Histopathologically Indra Sitorus; M Nur Salim; Nazaruddin Nazaruddin; Dwinna Aliza; Denny Irmawati; Awaluddin Awaluddin; Cut Nila Thasmi; Muslim Akmal; Dian Masyitha
Jurnal Medika Veterinaria Vol 14, No 2 (2020): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v14i2.4374

Abstract

This study aims to determine the effectiveness of 10% Jatropha salve (Jatropha curcas L. )    to inflammation reaction cutaneous wound healing in mice (Mus musculus ) in the inflammatory phase. This experiment used 9 male mices, weighing 25-40 grams and age 2-3 months old, were divided into three treatment groups, each treatment consisting of three mices. The wound were made along 2 cms in the back area. Wound therapy was carried out  twice a day for 3 days.  Group KI was administered  and given by yellow vaseline, KII was given 10% Jatropha salve, and KIII was given gentamicin salve. The parameters measured are the increase in the number infiltrations of inflammatory cells,  neovascular, and re-epitelization. All quantitative data were measured using ANOVA and continued with Duncan Test, the qualitative data were presented descriptively by showing the results of observation under a microscope. The statistical test on the infiltrations of inflammatory cells and neovasculars parameter 10% Jatropha salve group significantly different (P0.05) compared to KI and KIII group. Histopatologycal observations indicated the 10% Jatropha salve could be reduce the infiltrations of inflammatory cells, increase neovasculars and re-epitelization percentage. According to the result can be concluded the 10% Jatropha salve can accelerate the inflammation phase cutaneous wound healing in mice.
5. Antimicrobial Activity of Balakacida (Chromolaena odorata) Endophytic Bacteria Isolated from Aceh Besar Against Staphylococcus aureus and Pseudomonas aeruginosa Wahyu Eka Sari; Darmawi Darmawi; Morizka Wianda; Erina Erina; Rumi Sahara Zamzami; Muhammad Hambal; M. Nur Salim; Hennivanda Hennivanda; Triva Murtina Lubis
Jurnal Medika Veterinaria Vol 14, No 2 (2020): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v14i2.19415

Abstract

This study aims to isolate the balakacida (Chromolaena odorata) endophytic bacteria from Aceh Besar and to test its antimicrobial activity against pathogenic bacteria Staphylococcus aureus and Pseudomonas aeruginosa. Balakacida leaf samples were isolated and purified using nutrient agar (NA) media, followed by morphological observations and antimicrobial in vitro tests using a disk diffusion assay (Kirby Bauer). The results showed that a total of 50 endophytic bacterial colonies were isolated from the balakacida and 12 selected endophytic bacterial isolates had different morphologies from cream to yellowish cream color, then after antagonist test directly screening obtained four endophytic bacterial isolates which had the potential as antimicrobial. The results of in vitro antimicrobial tests showed that the four isolates of balakacida endophytic bacteria (BEA-1, BEA-2, BEA-3, and BEA-4) were able to inhibit the growth of pathogenic bacteria S. aureus and P. aeruginosa with the diameter of the zone of inhibition was 16.03 mm - 19.75 mm (medium inhibition category) and 15.35 mm - 21.24 mm (weak to strong inhibition category), respectively. Based on these results, it can be concluded that BEA-2 isolate has the strongest inhibition of 21.24 mm, so that it has the potential as an antimicrobial candidate for P. aeruginosa and can be used as an alternative antimicrobial product.
4. Case Study: Gallstones (Cholelithiasis) in Long-tailed Macaques (Macaca fascicularis) J. Susilo; B. Tri Wibowo; Y. Tinasari; M. Nur Salim; Dian Masyitha; Erdiansyah Rahmi; M. Isa; Herialfian Herialfian; Fakhrurrazi Fakhrurrazi; T. Fadrial Karmil; Fadli A. Gani
Jurnal Medika Veterinaria Vol 15, No 2 (2021): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v15i2.25204

Abstract

The purpose of this case study is to diagnose the cause of death of the long-tailed macaque (Macaca fascicularis). Two cadaver of Macaca fascicularis were received by the Lampung Veterinary Center from a customer. Necropsy was carried out at the Pathology Laboratory of the Lampung Veterinary Center by observing macroscopic changes. The samples taken were then observed by gram staining in the Bacteriology laboratory and hematoxylin-eosin staining at the Pathology laboratory. The results of macroscopic observations showed an enlarged gallbladder with a length of 4 cm and a width of 2 cm, blackish in color. Gallbladder surgery found 15 gallstones measuring 2 mm in diameter, brownish-colored bile, fibrin clots, and blood. The native gram stain of bile showed several types of rod-shaped bacteria form and gram-negative cocci (eosinophilic), and gram-positive rods (basophilic). Specific histopathological changes in the ductus choleductus are multifocal neutrophil inflammatory cell infiltration, enlarged gallbladder lumen filled with multi-bacterial, cell debris, fibrin, and erythrocytes. Multifocal hepatitis occurs by neutrophils, multibacterial, and fibrin. It can be concluded that the causes of death of Macaca fascicularis were cholelithiasis and hepatitis.
8. The Role of Bovine Viral Diarrhea Virus In Bovine Respiratory Disease Complex In Cattle Import Livestock At 2019 Periode J Susilo; J Siswanto; T. Fadrial Karmil; Rusli Rusli; M. Nur Salim; Zainuddin Zainuddin; Ginta Riady; Dasrul Dasrul; Fakhrurrazi Fakhrurrazi; Azhari Azhari; Andi Novita
Jurnal Medika Veterinaria Vol 14, No 1 (2020): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v14i1.17402

Abstract

Bovine viral diarrhea virus (BVDV) is one of the most important infectious diseases in cattle breeding. Bovine respiratory disease complex (BRDC) is a respiratory disease in mature and calf cattle which is a viral and bacterial superinfection including BVDV. The purpose of reseach is to study the role of BVDV in cases of Bovine respiratory disease complex (BRDC), especially with the characteristic of lesions were granulomatous pneumonia. The material in this study was lung tissue that was fixed with 10% formaldehyde buffer of calf sampel collected in October and November 2019. The sample is processed in a pathology laboratory for hematoxyline eosin (HE) staining and followed by immunohistochemical staining (IHC). A total of 11 lung samples sent from imported beef cattle and dairy cattle with a diagnosis of pneumonia complex morphology continued with CPI testing with monoclonal antibodies against bovine viral diarrhea virus. Nine samples showed positive CPI results against BVDV and two other samples were negative. Bovine viral diarrhea virus is detected in all granulomatous pneumonia, so it has an important role in BRDC. Early detection, treatment and prevention of BRDC affected or followed by BVDV must be carried out programmatically.
Efficacy of Jatropha (Jatropha curcas L.) Sap Cream on Total Differential Leucocytes in Inflammatory Phase of Wound Healing on Mice Skin (Mus musculus) : A Review Aufira Fildza Bahittah; M. Nur Salim; Triva Murtina Lubis; T. Zahrial Helmi; Abdul Harris; Wahyu Eka Sari
Jurnal Medika Veterinaria Vol 17, No 1 (2023): J.Med.Vet
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v17i1.23542

Abstract

A wound is a damage to the integrity of the epithelium of the skin. There are three phases of wound healing process, the first phase is inflammatory phase, the second phase is fibroplasia phase, and the third is maturation phase. Inflammation that occurs during the wound healing process should be limited because it would cause the wound to undergo an abnormal healing process and pathological inflammation if it persists. The aim of this study was to determine the efficacy of jatropha (Jatropha curcas L.) sap cream on total differential leucocytes in inflammatory phase of wound healing on mice skin. The method used was literature study using qualitatSive methods. Data used in this study refers to the result of studies which have been conducted and published in national and international online journal. Result of data analysis showed that Jatropha sap cream was effectively limiting and  inhibiting the leucocytes accumulation in inflammatory area and stimulated new blood vessels formation (angiogenesis) in inflammatory phase of wound healing in mice skin. Based on the result of this study, it can be concluded that the Jatropha sap cream could reduce the number of differential leucocytes in inflammatory phase of wound healing on mice skin.
PENGARUH PEMBERIAN EKSTRAK KULIT BATANG JALOH TERHADAP GAMBARAN MIKROSKOPIS GINJAL TIKUS PUTIH (Rattus novergicus) YANG DIINFEKSI (Trypanosoma evansi The Effect of Wilow Bark Ekstract Administration on Microscopic Feature of Male Rats (Rattus novergicus) Kidney Infected with Trypanosoma evansi) Nurdiniyah Nurdiniyah; Nazaruddin Nazaruddin; Sugito Sugito; M Nur Salim; Yudha Fahrimal; Siti Aisyah
Jurnal Medika Veterinaria Vol 9, No 2 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v9i2.3949

Abstract

The aims of this study was to examine the ability of willow bark extract to prevent kidney tissue damage from T. evansi infection. This study used 25 rats which were randomly divided into 5 treatment groups, each groups consisted of 5 rats. Rats in control group (K0) were not infected with T. evansi and without administration of willow bark extract. Group 1 (P1) was infected with 103/0,3 ml of T. evansi without willow bark extract administration. Group 2, 3, and 4 were infected with 103/0.3 ml T. evansi and received willow bark extract at dose of 30, 45, and 60 mg/kg bw, respectively. Willow bark extract were administered for 3 days consecutively. On day 4, the rats were sacrificed using chloroform and the kidneys were collected for histopathological examination. Data were analyzed descriptively. The results showed that the administration of willow bark extract at doses of 30 and 45 mg/kg bw were able to prevent damage of tubule cells and glomerular renal, while the administration of 60 mg/kg bw resulted in kidney damage, indicated by necrosis in tubular glomerular cells. It could be concluded that willow bark extract at doses of 30 and 45 mg/kg bw were effective to prevent tissue damage in kidneys.Key words: kidneys, willow, Trypanosoma evansi
33. Efficacy of Jatropha(Jatrophacurcas L.) Sap Cream in Inflammation Phase of Wound Healing on Mice Skin Hidayati Hidayati; Muhammad Nur Salim; Ummu Balqis; Dian Masyitha; Cut Dahlia Iskandar; Darmawi Darmawi; Abdul Harris
Jurnal Medika Veterinaria Vol 13, No 2 (2019): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v13i2.14565

Abstract

This study aim to know the efficacy of the jatropha sap cream toward the inflammatory phase of wound healing on the skin of mice. This study used 9 male mice, with 25-40 grams weights and 2-3 months old.  Male mice receiveddivided into 3 groups, and3 deuteronomy.The cut is done in the back as 2 cm long. Wound care is done twice a day at 08.00 am and at 18.00 pm for 3 days. The treatment I (PI) cuts smeared a cream base (as a negatif control); treatment II (PII) smeared 10% jatropha sap cream; and the treatment III (PIII) smeared 0.1% sulfadiazine  (as a positive control).Created a skin sample preparation microtechnic stained with hematoxylin-eosin (HE). The result on the number of infiltration of inflammatory cells and neovascular on PI; PII; and PIII were 402,00 ± 7,21 and 14,00 ± 5,57; 248,67 ± 1,53 and 34,67 ± 7,51; and 343,00 ± 8,89 and 28,00 ± 5,00  (P0,01). Based on the result it be concluded the treatment of 10% jatropha sap cream can speed up the process of the inflammatory phase of wound healing in the skin of mice.
Co-Authors Abdul Harris Amiruddin Amiruddin Andi Novita Aufira Fildza Bahittah Awaluddin Awaluddin Azhari Azhari B. Tri Wibowo Cut Dahlia Iskandar Cut Mentari Fatihah Amran Cut Nila Thasmi Darmawi Darmawi Darmawi Darmawi Dasrul Dasrul Denny Irmawati Dian Masyitha Dwinna Aliza Erdiansyah Rahmi Erina Erina Erwin E Etriwati E Fadli A. Gani Fakhrurrazi Fakhrurrazi Ginta Riady Hennivanda Hennivanda Herialfian Herialfian Hidayati Hidayati Indra Sitorus J Siswanto J Susilo J. Susilo M. Ikhsanuddin M. Isa Morizka Wianda Mudhita Zikkrullah Ritonga Muhammad Hambal Muslim Akmal Nazaruddin N Nazaruddin Nazaruddin Nurdiniyah Nurdiniyah Rezeki Indah Sari Rumi Sahara Zamzami Rusli r Rusli Rusli Rusli Rusli Sari, Wahyu Eka Siti Aisyah Sugito Sugito T. Armansyah T. Fadrial Karmil T. Fadrial Karmil T. Fadrial Karmil T. Zahrial Helmi Teuku Fadrial Karmil Teuku Zahrial Helmi Triva Murtina Lubis Ummu Balqis Wahyuni, Sri Y. Tinasari Yudha Fahrimal Zainuddin Zainuddin