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Journal : Jurnal Penelitian Kesehatan Suara Forikes

Jumlah Sel Neuron Cerebrum pada Paparan Musik Mozart Lebih Tinggi Dibandingkan Dengan Paparan Musik Indonesia Agustina Mar'atus Sholichah; Hermanto Tri Joewono; Widjiati Widjiati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11, No 1 (2020): Januari 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11104

Abstract

Background: Intelligence management can produce superior human resources with integrated brain. Mozart music stimulus during pregnancy has been shown to increase the number of neuron of the fetal brain. The study of pop and religious music needs to be improve because they are more popular in Indonesia. Objective: To analyze the differences of number of Neuron in the Cerebrum Rattus norvegicusoffspring that exposed to Mozart, Indonesian pop music and Indonesian religious music during pregnancy. Methods: An experimental study with a post-test only control group design. Groups divide into treatment music groups: Mozart, pop and religious. Treatment in a soundproof room for 1 hour, starting the 10th-day of pregnancy, intensity of 65 dB with a distance of 25 cm from the cage. The number of neuron was counted from HE brain preparations of the head Rattus norvegicusoffspring and analyzed using appropriate statistics test. Results: There were significant differences in the number of neuron of Rattus norvegicusoffspring in cerebrum between groups with p = 0,000 (mean Mozart music group 28.14 ± 3.02, Indonesian pop music 19.71 ± 1.80, Indonesian religious music 24.14 ± 2.91) and Mozart gave a higher number of neuron than Indonesia religious music and Indonesian pop music. Conclusion: Mozart music gave a higher number of neuron in the Cerebrum than Indonesian religious music and Indonesian pop music. Keywords: neuron; cerebrum; Mozart music; Indonesian music ABSTRAK Latar belakang: Pengelolaan kecerdasan otak yang terintegrasi akan menghasilkan SDM yang unggul. Stimulus musik Mozart selama kehamilan terbukti meningkatkan jumlah sel neuron di otak janin. Musik pop dan religi perlu dilakukan penelitian karena lebih populer di Indonesia. Tujuan: Menganalisis perbedaan jumlah sel neuron di Cerebrum Rattus norvegicusbaru lahir antara yang mendapat paparan musik Mozart, musik pop Indonesia dan musik religi Indonesia selama kebuntingan. Metode: Studi eksperimental dengan desain post test only control group. Kelompok perlakuan dibagi menjadi kelompok musik Mozart, musik pop Indonesia dan musik religi Indonesia. Perlakuan di ruang kedap suara selama 1 jam pada malam hari mulai hari ke-10 kebuntingan, intensitas 65 dB dengan jarak 25 cm antara kandang dan speaker. Jumlah sel neuron dihitung dari preparat pewarnaan Hematoxylin-Eosin otak anak Rattus norvegicusdan dianalisis dengan statistik yang sesuai. Hasil: Terdapat perbedaan yang signifikan pada jumlah sel neuron cerebrum Rattus norvegicus baru lahir antar kelompok dengan nilai p=0,000 (rerata kelompok musik Mozart 28,14±3,02, musik pop Indonesia 19,71±1,80 dan musik religi Indonesia 24,14±2,91) dan musik Mozart memiliki jumlah sel neuron lebih tinggi daripada musik religi Indonesia dan musik pop Indonesia. Kesimpulan: Kelompok musik Mozart memiliki jumlah sel neuron di cerebrum yang lebih tinggi dibandingkan kelompok musik Indonesia. Kata kunci: neuron; cerebrum; musik Mozart; musik Indonesia
Mozart Memberikan Hasil Indeks Apoptosis Lebih Rendah daripada Musik Pop, Religi dan Tanpa Pemberian Musik Dian Sukmawati; Hermanto Tri Juwono; Widjiati Widjiati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11, No 1 (2020): Januari 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11106

Abstract

Background: Brain growth requires genetic potential for a conducive environment, low stress levels, stimulation and nutrition. Brain development during the fetal period in the two years of life firstly requires proper stimulation to increase intelligence. Classical music stimulation has been proven to be able to optimally improve brain function and human intellect. Other music that Indonesian people like is pop and religion. Maybe it is possible to pop and religious music can affect the development and growth of the fetal brain. Objective: Analyze the differences of the index of apoptosis Cerebrum and Cerebellum Rattus norvegicus newborn between those stimulated by Mozart, pop, religious music and not stimulated by music during pregnancy. Method: This study was post test only control group design. groups were randomly divided according to the treatment as stimulation of Mozart, pop, religious music and no music was given from the 10th day-gestation with an intensity of 65 dB in a soundproof box for one hour. When 19th day-gestation, Rattus norvegicus mothers were sacrificed then 3 Rattus norvegicus newborn from each mothers were selected and brain was taken to be made immunohistochemical preparations and counted the number of neuron cells apoptosis index. data were analyzed by comparison test with p
Penetapan Total Flavonoid, Aktivitas Antioksidan dan Karakterisasi Nanopartikel Ekstrak Etanol Daun Kelor (Moringa pterygosperma Gaertn.) Tinta Julianawati; Hendy Hendarto; Widjiati Widjiati
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 11, No 1 (2020): Januari 2020
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf11110

Abstract

Moringa pterygosperma is one of the plants in Indonesia that is often used in herbal medicine. Moringa leaves contain many phytochemical compounds, one of the compounds is flavonoids which function as antioxidants. Flavonoid compounds in vitro can inhibit lipid peroxidation by breaking the chain of peroxyl radicals. Moringa leaf benefits in the field of herbal medicine are formed with a variety of preparations. One of the preparations is in the form of extracts with the aim of attracting chemical components to natural materials The extraction process has a disadvantage because the level of solubility in water is still low. The nanoparticle technique is a strategy to increase the bioavalbicibility of herbal active compounds. This research was experimental in order to determine the total flavonoid levels contained in Moringa leaf extract. In addition, it was also to find out the antioxidant activity and particle size of the moringa leaf extract nanoparticles. Determination of flavonoid levels using spectrophotometric methods. The antioxidant activity of moringa leaf extract nanoparticles was tested using the DPPH method (2,2-diphenyl-picrylhdrazyl) and to determine the particle size used by using the Particle Size Analyzer (PSA). The results of the study showed total flavonoid levels in moringa leaf extract (1.97 ± 1.07)%. Antioxidant activity of 451.8 ppm with a reduction of 2.8% and particle size in the moringa leaf extract nanoparticles of ± 134.78 nm. Moringa leaf extract nanoparticles include low antioxidants. Keywords: moringa; nanoparticles; antioxidants