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All Journal AL KAUNIYAH Pharmascience Jurnal Surya Medika JKM (Jurnal Kebidanan Malahayati) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Farmasi Indonesia Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Journal of Engineering, Technology, and Applied Science (JETAS) Indonesia Berdaya Community Empowerment Ruang Cendekia : Jurnal Pengabdian Kepada Masyarakat Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan Journal of Pharmaceutical Care and Sciences Jurnal Rumpun Ilmu Kesehatan Jurnal Sains dan Kesehatan Jurnal Keperawatan Innovative: Journal Of Social Science Research Sains Medisina Health Research Journal of Indonesia Indonesian Journal of Pharmacy and Natural Product Majalah Cendekia Mengabdi Promotor: Jurnal Mahasiswa Kesehatan Masyarakat Jurnal Farmasi SYIFA El-Mujtama: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Wadah Publikasi Cendekia
Ali Rakhman Hakim
Universitas Sari Mulia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal Surya Medika

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Potensi Antimikroba Ekstrak Etanol Kulit Luar Buah Cempedak (Artocarpus integer (Thunb.) Merr.) Rina Saputri; Ali Rakhman Hakim; Dahlia Syahrina; Fatthiya Lisyanti
Jurnal Surya Medika (JSM) Vol 5 No 1 (2019): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.188 KB) | DOI: 10.33084/jsm.v5i1.945

Abstract

The background of this research is to develop the potential of biological resources in South Kalimantan. In particular, the biological source is cempedak fruit. The use of cempedak which has been scientifically studied is the use of cempedak bark as anti-malaria. Other studies related to other parts of cempedak are still not widely used. Based on the potential possessed by cempedak bark, it is likely that other parts of cempedak also have potential as traditional medicine. This study aims to identify the content of secondary metabolites from the outer skin of cempedak fruit, analyze the potential of the outer skin of cempedak fruit as an antimicrobial and analyze the effective dose as an antimicrobial. The method used to see MIC values with liquid dilution and KBM values with solid dilution. The results of phytochemical identification showed that the ethanol extract of the outer skin of cempedak fruit contained secondary metabolites in the form of saponins, tannins, flavonoids and alkaloids which have antimicrobial potential. The results of the antimicrobial activity test showed the MIC value of the ethanol extract of cempedak fruit outer skin against Escherichia coli bacteria at a concentration of 50% and against Staphylococcus aureus at a concentration of 25%. The KBM value also shows the same value as KHM. Based on the results of the study it can be concluded that the ethanol extract of cempedak fruit outer skin has broad-spectrum antimicrobial activity.
Narrative Review: Optimasi Etanol sebagai Pelarut Senyawa Flavonoid dan Fenolik Ali Rakhman Hakim; Rina Saputri
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1641

Abstract

The use of ethanol as a solvent for secondary metabolite compounds is very widespread. Ethanol can dissolve flavonoid compounds and phenolic compounds from plants. To be able to utilize ethanol as a solvent is dependent on some factors of concentration, temperature, time, and selection of extraction methods. This study uses the method by searching scientific articles from the MDPI website database. The Ultrasound-Assisted Extraction (UAE) method is very suitable for the optimization of ethanol as a solvent. The optimal use of ethanol is in the concentration range of 50-80%, temperature conditions in the range of 40-70ºC, and the extraction time is in the range of 30 minutes - 24 hours.
Narrative Review: Implementasi Distribusi Obat yang Baik di Pedagang Besar Farmasi Mustaqimah Mustaqimah; Rina Saputri; Ali Rakhman Hakim
Jurnal Surya Medika (JSM) Vol 6 No 2 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i2.2128

Abstract

Distribution of pharmaceutical products from the pharmaceutical industry before reaching the pharmacy service point must be through wholesale. Good distribution practice methods are a set of standardized routine working methods, which ensure the quality, safety, and efficacy of pharmaceutical products remain intact from the very beginning to the end of the expiration period. Good distribution practice methods must be implemented by all wholesale in Indonesia so that wholesale operations can run effectively and efficiently. All pharmaceutical wholesalers must have standard operating procedures, personnel with integrity, and a good documentation system.
Analisis Faktor yang Berhubungan dengan Kepatuhan Pasien di Kabupaten Banjar Mustaqimah Mustaqimah; Rina Saputri; Ali Rakhman Hakim; Reny Indriyani
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2659

Abstract

Hypertension is still the most common disease in the world. South Kalimantan Province in 2018 became the province with the highest number of hypertension sufferers in Indonesia. Hypertensive patients will undergo hypertension therapy for the rest of their lives so that blood pressure can still be well controlled. Lifelong therapy can reduce patient compliance in taking hypertension drugs; this can result in failed therapeutic goals and lead to the emergence of other diseases such as myocardial infarction and others. The purpose of this study was to analyze sociodemographic factors and clinical factors that may be related to patient compliance in taking hypertension drugs in Banjar Regency. The results showed that the majority of respondents had low compliance in consuming hypertension drugs. The analysis showed that sociodemographic factors such as gender, age, occupation, and place of getting the drug and clinical factors in the form of drugs used and blood pressure control did not show a significant relationship. The education factor shows a p-value < 0.05, which indicates the education factor has a significant relationship.
Analisis Toksisitas Akut Kombinasi Captopril dengan Rebusan Daun Sirsak pada Tikus Galur Wistar Rina Saputri; Mustaqimah Mustaqimah; Ali Rakhman Hakim
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2849

Abstract

Hypertension is a degenerative disease that requires lifelong therapy. Along with the development of time, nowadays people are more interested in consuming traditional medicine, especially by using plants. In addition to consuming soursop leaf decoction, people also continue to use conventional medicine to help control hypertension. The combination of conventional medicine and traditional medicine can cause unwanted reactions if not used in the right dosage, one of which is the risk of acute toxicity. Until now there is no published data showing the acute toxicity analysis of the combination of captopril with soursop leaf decoction. The purpose of the study was to determine the maximum dose of the combination of captopril and soursop leaf decoction that could be used. The method used in this study is an advanced experimental study with a random block design using 30 test animals divided into 10 groups. The results of the acute toxicity test conducted did not show any death of the test animals within 24 hours and up to 7 days of observation in all experimental groups. The results of the physical observation test for 7 days showed that all rats were in normal condition in all experimental groups. The conclusion of this study is that the combination of captopril up to a dose of 150 mg/day (dose in humans before conversion to test animals) + soursop leaf decoction with an effective dose of 300 ml (dose in humans before conversion to test animals) did not show any death and symptoms toxicity in test animals.
Aktivitas Antioksidan Kulit Buah Cempedak (Artocarpus integer (Thunb.) Merr.) asal Kalimantan Selatan Ali Rakhman Hakim; Rina Saputri; Amanda Shelvia Savitri; Anisa Ujuldah; Fitri Sadlia
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.2858

Abstract

The increasing incidence of diseases related to oxidative stress among the human population has led to an increase in the consumption of natural antioxidants in the human diet. The purpose of this study was to determine the antioxidant activity of cempedak fruit skin extract with 50% ethanol and 70% ethanol as solvents. The method used was testing of radical inhibitory activity with the DPPH method (1,1-diphenyl-picrylhydrazil) and as a positive control was vitamin C. The results of phytochemical screening were known to contain phenolics, flavonoids, and tannins. The results of the antioxidant activity of E50% obtained IC50 values of 650.07 ppm and IC50 of E70 of 1219.69 ppm. From these results, it can be concluded that the skin of the cempedak fruit does not have antioxidant activity.
Karakterisasi dan Formulasi Nanopartikel Ekstrak Tanaman Bundung (Actinoscirpus grossus) dengan Variasi Konsentrasi Basis Kitosan dan Na-TPP Menggunakan Metode Gelasi Ionik: Characterization and Formulation of Nanoparticles Extract of Bundung Plant (Actinoscirpus grossus) with Variations in Concentration of Chitosan and Na-TPP Bases Using the Ionic Gelation Method Yuditha Mutia Windy; Khaliza Natasya Dilla; Jesika Claudia; Noval Noval; Ali Rakhman Hakim
Jurnal Surya Medika (JSM) Vol. 8 No. 3 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v8i3.4495

Abstract

Bundung plant extract contains flavonoid secondary metabolite compounds that have the potential to kill Staphylococcus aureus bacteria and inhibit the fungus Candida albicans. Its utilization uses nanoparticle technology because the ability to penetrate cell walls can be penetrated by the size of colloidal particles. Nanoparticles are technologies that have a size of 10-1000 nm. The formation of nanoparticles using chitosan polymer and Na-TPP can produce preparations with good stability. This study aims to determine the characterization and formulation of nanoparticles and the effect of the concentration of chitosan and Na-TPP on the characterization of nanoparticles of plant extracts. This research is an experimental laboratory with a quasi-experimental design method and a one-group posttest-only research design. Bundung plant extracts formulated into nanoparticles with various concentrations of formula 1 (chitosan 0.1% and Na-TPP 0.2%), formula 2 (chitosan 0.15% and Na-TPP 0.15%), and formula 3 (chitosan 0.2% and Na-TPP 0.1%). Then organoleptic and characterization tests were carried out in particle size tests, zeta potential, and data were analyzed by ANOVA. All formulas showed nanoparticle size. The results of the nanoparticle characterization of the extract of the Bundung plant showed that F2 was the formula with the smallest particle size of 328.8 nm, but for the zeta potential value, the stable formula was F3 because it had a zeta potential value close to +/-30mV, i.e., 10.4mV. The statistical results of One Way ANOVA show that the significance value is <0.05, which means that there is an effect of variations in the concentration of chitosan and Na-TPP. Variations in the concentration of chitosan and Na-TPP in each formula can affect the particle size and zeta potential value.
Kajian Etnomedisin Masyarakat Desa Sungai Rangas Ulu: Ethnomedical Study of The Sungai Rangas Ulu Village Community Mustaqimah, Mustaqimah; Saputri, Rina; Hakim, Ali Rakhman; Indriyani, Reni
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.8340

Abstract

Penggunaan obat tradisional umum dilakukan oleh masyarakat di negara-negara berkembang. Selain itu, masyarakat desa juga masih memiliki tradisi yang kuat dalam praktik pengobatan tradisional khususnya pemanfaatan tanaman atau bagian tanaman sebagai obat. Penelitian ini bertujuan untuk mendokumentasikan pengetahuan tradisional tentang tanaman obat yang digunakan untuk menyembuhkan berbagai penyakit dan mengubah pengetahuan lisan tentang penggunaan tradisional tanaman obat menjadi laporan ilmiah tertulis. Metode penelitian yang digunakan adalah analisis deskriptif. Alat yang digunakan adalah kuesioner. Responden penelitian sebanyak 20 orang dari desa sungai rangas ulu. Dari hasil penelitian didapatkan sebanyak 29 jenis tanaman telah digunakan oleh masyarakat, dengan bagian tanamannya berupa akar, batang, biji, buah, daun, dan rimpang. Tanaman terbanyak berdasarkan nilai Use Value adalah daun salam.
Analisis Faktor-Faktor Terjadinya Kasus Preeklamsi pada Ibu Hamil di Wilayah Kerja PKM Perawatan Satui: Analysis of Factors in the Occurrence of Preclamsi Cases in Pregnant Women in the Working Area of PKM Satui Fahriani, Fahriani; Salmarini, Desilestia Dwi; Hakim, Ali Rakhman; Lestari, Yayuk Puji
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9674

Abstract

Preeklamsi adalah gangguan spesifik hipertensi yang disebabkan oleh kehamilan pada usia kehamilan >20 minggu yang disertai gangguan sistem organ. Pada tahun 2022 kasus preeklamsi berada diurutan ketujuh dan menyumbangkan 3 kasus kematian ibu di Kabupaten Tanah Bumbu. Tujuan penelitian adalah menganalisis faktor-faktor terjadinya kasus preeklamsi pada ibu hamil di wilayah kerja Puskesmas Perawatan Satui. Metode survei analitik desain case control. Jumlah sampel pada penelitian ini adalah 122 orang. Sampel kasus ditentukan dengan teknik purposive sampling yaitu semua ibu hamil yang terdiagnosa preeklamsi sebanyak 61 orang, sedangkan sampel kontrol diambil dengan teknik simple random sampling sebanyak 61 orang. Pengumpulan data dengan cara melihat buku register dan rekam medik lalu dianalisis secara univariat dan bivariat dengan menggunakan analisis Spearman Rho dengan tingkat kepercayaan 95% (α=0,05). Didapatkan hasil ada hubungan yang signifikan antara pendidikan dengan kasus preeklamsi dengan nilai sig. Spearman Rho=0,033, OR=2,331 (1,063-5,112) dan RR=1,6. Ada hubungan yang signifikan antara riwayat hipertensi dengan kasus preeklamsi dengan nilai sig. Spearman Rho=0,000, OR=tidak bisa terbaca dan RR=3,5. Tidak ada hubungan yang signifikan antara umur dengan kasus preeklamsi dengan nilai sig. Spearman Rho =0,100, OR=1,843 (0,890-3,820) dan RR=1,3. Tidak ada hubungan yang signifikan antara paritas dengan kasus preeklamsi dengan nilai sig. Spearman Rho =0,589 OR=1,220 (0,597-2,492) dan RR=1,1. Kesimpulan dari penelitian ini ada hubungan yang signifikan antara pendidikan dan riwayat hipertensi dengan kasus preeklamsi dan tidak ada hubungan signifikan antara umur dan paritas dengan kasus preeklamsi.
Uji Toktisitas Ekstrak Metanol Daun Leunca (Solanum Ningrum L.) Terhadap Larva Artemia Salina Leach dengan Metode Brine Shrimp Lethality Test (BSLT): Toxicity Test of Methanol Extract of Leuna Leaves (SolanumNingrum L.) Towards Artemia Salina Leach Larvae Using Brine Shrimp Lethality Test (BSLT) Method Martha, Dhea Yolanda; Hakim, Ali Rakhman; Yuwindry, Iwan; Rohama, Rohama
Jurnal Surya Medika (JSM) Vol. 11 No. 2 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.10527

Abstract

Kanker merupakan suatu penyakit yang menjadi perhatian dalam dunia kesehatan serta merupakan salah satu penyakit yang menjadi perhatian serius pada bidang kesehatan, tidak terkecuali pada bidang farmasi. Kanker dapat menyebabkan kematian bagi penderitanya. Sebanyak 9,6 juta orang meninggal karena menderita kanker dan 57% terjadi di benua Asia. Pencarian obat antikanker berbasis bahan alam perlu dikembangkan dengan memanfaatkan potensi sumber daya alam Indonesia yang kaya dengan floranya. Leunca (Solanum nigrum L.) adalah salah satu tumbuhan yang memiliki aktivitas antikanker dan merupakan tanaman obat yang biasanya dijadikan simplisia dari bagian daun maupun buah. Tanaman leunca secara empiris mencegah gangguan kanker, yakni kanker payudara. Kandungan kimia dari tanaman leunca yaitu alkaloid, flavonoid, fenol, dan steroid.
Co-Authors AA Sudharmawan, AA Adriana Palimbo, Adriana Agenia Rahman Agustin, Nur Syafa Ahmad Hidayat Ahmad Syahlani Ahnafani, Miyada Nur Aima Pitriya amanah, nurul Amanda Shelvia Savitri Amanda Shelvia Savitri Amanda Shelvia Savitri Amanda Shelvia Savitri Anggia Puteri Anisa Ujuldah Anisa Ujuldah Annisa Fitria Ariani, Malisa Aryzki, Saftia Asi, Seva Bela N. Asi, Seva Bela Nata Asti Wulan Ariani Auli Damayanti Aulia Damayanti Aulia Rahmah Aulia, Nina AYU LESTARI Azhimia, Faida Bayu Hari Mukti Carolin, Putri Dahlia Syahrina Dede Mahdiyah Dede Mahdiyah, Dede Defitamira, Olvi Deviani, Norma Dian Bardiansyah Donaretsi, Olga Nathania Dwi Salmarini, Desilestia Elieser, Michael Endang Susilawati Enzelia, Yoan Esti Susilowati Evana, Nur Qomara Fadhiyah Noor Anisa Fahriani, Fahriani Fatthiya Lisyanti Faulina, Siti Emi Az-Zahra Fitri Sadlia Fitri Yuliana Fitri Yuliana, Fitri Fitriani, Dyah Fitriyana, Rahma Furqan, Rizqi Nur Giopani, Dea Lailani Gresia, Sola Gumarus, Ellora Griselda Habibah, Nor Hariyanto, Ario Yudo Heny Novarita Hepriana, Yemima Holilah, Shafira Nor I Ketut Purnama Putra Ikeh, Tri Sulapmi D. Indriyani, Reni Ismiadi, Rahmad Jannah, Ghina Raudhatul Jesika Claudia Johanda, Maulida Karina, Diah Karinda, Niken Adkah Khaliza Natasya Dilla Komaliya, Risyda Kornelia, Sindi Kurniawati, Darini Kusuma D, Muhammad Chandra Hadi L. Lisnawati Laetare, Tresy Patricia Laurensia Yunita Lestari, Noor Laili Mega Lestari, Yayuk Puji Lisaura, Inggrit Windy M. Sobirin Mohtar Maharani, Silvia Atwi Maharani, Tri Anita Mahdalena Mahdalena Martha, Dhea Yolanda Marwah, Jannatul Maskura, Nur Maulani, Eka Febrianti Maulina, Nor Ma’rifah, Nurul Melviani, Melviani Mia Audina Mia Audina, Mia Miftahul Jannah Mohammad Basit, Mohammad Muhammad Aldi, Muhammad Muhammad Naufal, Muhammad Mustaqimah Mustaqimah Muzdalifah, Nur Nabila, Putri Nasiroh Nasiroh, Nasiroh Nastiti, Kunti Natantri, Bamikha Priskila Nayaken, Putri Olivia Ngongo, Marselina Nisa, Karimatun Nisrina, Salwa Nita Hestiyana nofrizal, deni Noorhaliza Noval Noval Noval Novalia Widiya Ningrum, Novalia Widiya Novalis, Rima Nugraha, Dyan Fitri Nur Hidayah NURUL HIDAYAH Oktavia, Regina Pebriana, Olvia Putri Pratiwi, Sinta Puji Lestari, Yayuk Puteri Putri Vidiasari Darsono Putri Vidiasari Darsono, Putri Vidiasari Putri, Mela Julia Rabiatul Adawiyah Rahayu, Desi Dwi Rahmadani Rahmadani Rahmadani Rahmadani Rahmah, Mulia Rahman, Agenia Ramadhan, Ahmad Dian Ramadhan, Novalina Rossa Ramadhani, Alya Raudhatul Jannah, Ghina Reny Indriyani Ria Fitriani Rina Saputri Rizali, Muhammad Rohama , Rohama Rohama, Rohama Rubina, Miranda Rustiana Rustiana Sadlia, Fitri Sagita, Ririn Samara, Akhmad Fadhil Saniah, Husnus Sari, Nita Wulan Sari, Rani Normaya Satria, Romi Savitri, Amanda Shelvia Setia Budi Sihotang, Ina Yunita Siti Azizah Siti Fatimah Siti Jubaidah, Siti Siti Malahayati Siti Sarah, Siti Sitti Khadijah Sofiya Maulida Sudarya, Maharani Fitria Syari, Aulia Rahma Syifa Khairunnisa syifa, Nur Syifa, Umi Tambun, Madschen Sia Mei Ol Siska Selvija Tuti Alawiyah Tuti Alawiyah Ujuldah, Anisa Ulfah, Annisa Utami, Putri Nadila Vania, Risma Ananda Weliyanto, Yupi Winda, Nadia Oktavia Wineiniati, Noni Wulandari, Suci Sri Yasnatasya Ys, Jian Yuditha Mutia Windy Yuli Yanti Sholehah Yustian, Alifira Adhany Yuwindry, Iwan Zahratunnisa, Zahratunnisa Zhafirah, Nurul Zulianur, Riska Ali Zulliati Zulliati