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All Journal Jurnal Kimia Mulawarman The Indonesian Biomedical Journal Majalah Kesehatan FKUB Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Ilmiah Manuntung Jurnal Abdimas Mandiri Jurnal Kebidanan Mutiara Mahakam Buletin LOUPE (Laporan Umum Penelitian) Jurnal Kesehatan Pasak Bumi Kalimantan Jurnal Kedokteran Mulawarman International Journal of Multidisciplinary: Applied Business and Education Research Jurnal Medika: Karya Ilmiah Kesehatan Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Indonesian Journal of Pharmacology and Therapy Proceeding Mulawarman International Conference on Tropical Public Health
Nataniel Tandirogang
Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Jurnal Sains dan Kesehatan

 1 
Potensi Ekstrak Etanol Rimpang Jeringau (Acorus calamus L.) Sebagai Spasmolitik Marihot Pasaribu; Nataniel Tandirogang; Sjarif Ismail; Swandari Paramita; Agustina Rahayu Magdaleni; Hary Nugroho
Jurnal Sains dan Kesehatan Vol. 1 No. 7 (2017): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i7.53

Abstract

Pain due to smooth muscle stiffness can occur in various circumstances of patients, ranging from normal circumstances such as menstrual pain, to a pathological condition of gastrointestinal infections. To overcome the pain it can be given medication to reduce muscle stiffness as spasmolytics, but there are side effects of the drug. Thus, the need for developing new spasmolytics drugs based on medicinal herbs with fewer side effects. This study was conducted to examine the potential of rhizome extract of jeringau (Acorus calamus L.) that is traditionally used by Dayak tribe to heal upset stomach. Spasmolytic activity of plant extracts tested with isolates organ methods of guinea pig ileum induced by histamine. Result of the study showed 0.3 mg/ml A. calamus rhizomes extract could decrease ileum contraction better than papaverine 0.03 mg/ml (p=0.00). The conclusion of this study is rhizome extract of jeringau (A. calamus) has the potential to be used as spasmolytics in treatment of health problems caused by smooth muscle contraction
Aktivitas Antimikroba Ekstrak Daun Karamunting (Melastoma malabathricum L.) Terhadap Bakteri Penyebab Diare Nataniel Tandirogang; Swandari Paramita; Yadi Yasir; Yuniati Yuniati; Meiliati Aminyoto; Evi Fitriany
Jurnal Sains dan Kesehatan Vol. 1 No. 7 (2017): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v1i7.54

Abstract

Diare hingga kini masih merupakan masalah kesehatan utama di Indonesia. Pemberian antibiotik merupakan salah satu upaya penatalaksanaan diare, namun belakangan terkendala masalah adanya resistensi terhadap antibiotik. Berdasarkan hal tersebut, maka upaya pencarian sumber antimikroba baru berbasis tumbuhan obat perlu dilakukan. Penelitian ini dilakukan untuk menguji potensi ekstrak daun karamunting (Melastoma malabathricum L.) yang secara tradisional digunakan etnis Dayak sebagai obat diare. Aktivitas antimikroba ekstrak tumbuhan diuji terhadap 5 bakteri standar; Escherichia coli ATCC 35128, Shigella sonnei ATCC 25931, Campylobacter jejuni ATCC 33291, Pseudomonas aeruginosa ATCC 15442, dan Enterobacter cloacae ATCC13047. Pengukuran aktivitas antimikroba dilakukan dengan disc diffusion method (Kirby-Bauer) dan pengukuran minimum inhibitory concentration (MIC). Hasil penelitian menunjukkan ekstrak daun M. malabathricum dapat menghambat pertumbuhan seluruh bakteri uji, dengan diameter zona hambat sebesar 12,3-16 mm dan MIC sebesar 2,3-13,3 mg/ml. Kesimpulan penelitian ini adalah ekstrak daun M. malabathricum berpotensi sebagai antidiare berdasarkan aktivitas antimikrobanya.
Gambaran Pasien Papil Atropi Di RSUD Abdul Wahab Sjahranie Samarinda Tahun 2015-2020: Overview of Optic Atrophy Patients at Abdul Wahab Sjahranie Hospital, Samarinda in 2015-2020 Budi Santoso Nong Ulir; Nur Khoma Fatmawati; Nataniel Tandirogang
Jurnal Sains dan Kesehatan Vol. 5 No. 1 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i1.1742

Abstract

Optic atrophy is the end process of a disease that causes degeneration of axons along the pathway to the lateral retinogeniculate bodies. Previous studies regarding the optic atrophy have had different results. This study was conducted to determine the description of optic atrophy patients at Abdul Wahab Sjahranie Hospital Samarinda in 2015-2020. This retrospective descriptive study was conducted in February 2021. Data were obtained from 64 patients who were taken by purposive sampling technique at Abdul Wahab Sjahranie Hospital, Samarinda. This study used a medical record sheet as a research source. This study found that the most common types of optic atrophy were secondary optic atrophy with 20 patients (83,3%). The highest age group of patients with optic atrophy was the 45-55 years group with 17 patients (26.6%). The most prevalent gender was male as many as 37 patients (57.8%). Eyes affected by optic atrophy were bilateral or both eyes with 34 patients (53,1%). Most of the patients with optic atrophy had visual acuity below 3/60 or experienced blindness with 44 eyes (67.7%). Eye disease was the most comorbid group with a total of 26 patients (35,1%). The most comorbidities were retrobulbar neuritis with 11 patients (14,9%). Keywords: optic atrophy, description, age, eyes Abstrak Papil atropi adalah proses akhir dari suatu penyakit yang menyebabkan degenerasi akson pada sepanjang jalur menuju badan retinogenikulatum lateralis. Penelitian sebelumnya mengenai gambaran papil atropi memiliki hasil yang berbeda. Penelitian ini dilakukan untuk mengetahui gambaran pasien papil atropi di RSUD Abdul Wahab Sjahranie Samarinda tahun 2015-2020. Penelitian ini bersifat desktiptif retrospektif yang dilakukan pada bulan Februari 2021. Data diperoleh dari 64 pasien yang diambil dengan teknik purposive sampling di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian ini menggunakan lembar rekam medik sebagai sumber penelitian. Penelitian ini mendapatkan jenis papil atropi terbanyak adalah jenis papil atropi sekunder sebanyak 20 pasien (83,3%). Kelompok usia pasien papil atropi tertinggi adalah kelompok usia kelompok 45-55 tahun sebanyak 17 pasien (26,6%). Jenis kelamin terbanyak adalah laki-laki sebanyak 37 pasien (57,8%). Mata yang terkena papil atropi terbanyak adalah bilateral atau kedua mata sebanyak 34 pasien (53,1%). Tajam penglihatan pasien papil atropi terbanyak adalah tajam penglihatan dibawah 3/60 atau mengalami kebutaan sebanyak 44 mata (67,7%). Penyakit mata adalah kelompok penyakit penyerta terbanyak dengan jumlah sebanyak 26 pasien (35,1%). Penyakit penyerta terbanyak adalah neuritis retrobulbar sebanyak 11 pasien (14,9%). Kata Kunci: papil atropi, gambaran, usia, mata
Co-Authors Abdullah, Yenny Adi Susanto Alhawaris, Alhawaris Anggraini, Fitria Dewi Puspita Arfian Deny Prakoso Azkiah, Wa Ode Nurul Bakhtiar, Rahmat Bilqis Faiqotun Nabilah Dilan Binti Khairunnisa Budi Santoso Nong Ulir Danial Danial Daniel Daniel Edy Wibowo Kurniawan Enih Rosamah Enjelina Febri Adi Melinia Enos Tangke Arung, Enos Tangke Evi Fitriany Fadilla, Shella Fikriah, Ika Harlinda Kuspradini Hary Nugroho Irawan Wijaya Kusuma, Irawan Wijaya Ivan Joalsen Mangara Tua Khairunnisa, Binti Khemasili Kosala Khemasili Kosala Krispinus Duma Magdaleni Agustina Rahayu Marihot Pasaribu Meiliati Aminyoto Miftahul Jannah Moerad, Emil Bachtiar Ningrum, Yuliana Kartika Nur Khoma Fatmawati Nurkhalisa, Nina Nursaci Mardania Nurul Fatimah Nurul Khumaida Nuryanto, Muhammad Khairul Pramulia Yudia, Riries Choiru Rahmat Bakhtiar Rasendriya , Fauzan Firjatullah Rasendriya, Fauzan Firjatullah Rosamah, Enih Rudito Sapta Rahayuning Ratri Saputra, Rudi Septa Ariany Silvia Anitasari Sjarif Ismail Sormin, Hendro Jatmiko Sukemi Sukemi Suwadi Swandari Paramita Yadi Yadi Yadi Yadi Yasir Yadi, Yadi Yuliana Kartika Ningrum Yulianti, Martina Yundari, Yundari Yung Kang Shen Yuniati Yuniati