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All Journal Prosiding Seminar Biologi AL KAUNIYAH Biosfer: Jurnal Tadris Biologi Prosiding Pendidikan Sains Jurnal Inovasi Teknologi Pendidikan Folia Medica Indonesiana Jurnal Farmasi Klinik Indonesia Bioeksperimen: Jurnal Penelitian Biologi Jurnal Pendidikan Biologi Journal of Biology Education AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Jurnal Penelitian Pendidikan IPA (JPPIPA) BIOEDUKASI PEDAGOGIA Biosfer: Jurnal Pendidikan Biologi JBN (Jurnal Bedah Nasional) Bioedukasi: Jurnal Pendidikan Biologi Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Bioedusiana: Jurnal Pendidikan Biologi JURNAL MEDIA KESEHATAN Journal of Pharmaceutical Care Anwar Medika Bioscientist : Jurnal Ilmiah Biologi MAHESA : Malahayati Health Student Journal DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN Molekul: Jurnal Ilmiah Kimia Biosaintifika: Journal of Biology & Biology Education Proceeding of International Conference on Biology Education, Natural Science, and Technology
UMI FATMAWATI
Program Studi Pendidikan Biologi/FKIP-Universitas Sebelas Maret, Surakarta, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Jurnal Penelitian Pendidikan IPA (JPPIPA)

 1 
Application of Project-Based Learning and Discovery Learning in Virtual Media on Analytical Thinking Skills for Animal Classification Puti, Tunjung Nala; Karyanto, Puguh; Fatmawati, Umi
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.4635

Abstract

This study aims to determine the characteristics of project-based learning and discovery learning virtual media on animal classification material and test the effectiveness of project-based virtual media discovery learning on animal classification material on analytical thinking skills. This research is a mixed type of research. The research design used is the exploratory sequential design, using qualitative data analysis as the initial stage and then used as a direction to determine the formulation of research problems, samples, and quantitative data collection methods, followed by the development of virtual media instruments based on project-based learning and discovery learning. Quantitative methods are applied using quasi-experimental research. The study design used a nonrandomized control group and a pretest-posttest design. The treatment class uses PjBL-based virtual media Iimplementation, the control class uses a virtual media discovery model-based. The test instrument used is an essay question to measure analytical thinking skills adapted from Brookhart. Data analysis using ANCOVA (p = 0.05%) with prates as covariates. The result of the differences in the characteristics of project-based learning and discovery learning virtual media lies in the syntax of learning models, virtual activities, work produced, and attitudes developed. The feasibility test results of both virtual media were declared suitable for use. The results of ANCOVA showed that project-based virtual media learning is more effective in improving analytical thinking skills than discovery-based virtual media learning.
Molecular Docking of Gamma Amino Butyric Acid GABA on Rattus Norvegicus B-receptor as Antidiabetic Indrowati, Meti; Harlita; Fatmawati, Umi; Ariyanto, Joko; Retnaningtyas, Estu
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.8044

Abstract

Earlier research reported that GABA had a correlation with diabetes in processes of glucose homeostasis. This study aims to identify the validity of B-receptor Rattus norvegicus as GABA protein target, modeling the structure and knowing the binding affinity between GABA and B-receptor Rattus norvegicus through molecular docking.   The research was carried out using in-silico method.  The interaction of GABA with the target protein was determined using SuperPred, followed by modeling the protein target using SwissadMe. Ramachandran Plot and Errat Procheck are used to determine the validity of the protein target. Molecular docking was determined using Pyrx and PyMol. The results showed that GABA binding to the B- receptor Rattus norvegicus has biological activity as glucose oxidase inhibitor and antidiabetic.  The conclusion are: B-receptor Rattus norvegicus is a valid protein target for binding to GABA; there are four 3-dimensional models of B-receptor Rattus norvegicus and the best model has 98.43% sequence identity; the binding affinity of GABA (ligand) on B-receptor Rattus norvegicus from the best model is -3.4 kcal/mol energy, 1.773 RMSD lower bound, and 1.81 RMSD upper bound. It is suggested that this research might be used as an empirical basis to further investigate GABA as antidiabetic.
Co-Authors Agustini, Lukisiari Anggraini, Meisi Anjani, Fullaikhah Arafa, Maretania Aryanti, Yuni Azis, Fahmi Dimas Abdul Bowo Sugiharto Budi Suprapti Dewi Puspita Sari Diharjo, Dewi DWI OETOMO ESTU RETNANINGTYAS N Fiqhunnisa, Anindita Handayani, Sri Harlita Harlita Harlita Havyarimana, Célestin Herawati, Fauna Herni Setyawati Hidayati, Movita I Wayan Gede Saraswasta Joko Ariyanto Mahanani, Lina Mansur, Mifta Maulida, Meirina Nur Meti Indrowati Nuraini Annisa, Nuraini Nuridha Fauziyah Nurmiyati Nurmiyati Nurmiyati Permatasari, Vera Prameselly, Qorisha Lutfia Prastya, Muhamad Eka Primahana, Gian PUGUH KARYANTO Puti, Tunjung Nala Reza, Salsabiela Praha Karima Riezky Maya Probosari Rosita, Lisa Rr Tutik Sri Hariyati Rumulus, Rasyidin Sajidan Sajidan Setiani, Indra Slamet Santosa Soedarsono Soedarsono Sri Dwiastuti Suharyati, Titin Suranto Suranto Ummi Nur Afinni Dwi Jayanti, Ummi Nur Afinni Utomo, Tegar Budi yati, indri Yudi Rinanto Yulistiani Yulistiani, Yulistiani Yuniar, Rizka Zienitha, Anggie Meilinda