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Journal : Media Farmasi Indonesia

ANALISIS PENGARUH PERENDAMAN LARUTAN KULIT SINGKONG (Manihot esculenta Cortex) TERHADAP KANDUNGAN LOGAM BERAT TIMBAL (Pb) DALAM KERANG DARAH (Anadara granosa) Susanti, Maria Mita; Priamsari, Margareta Retno
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.435 KB)

Abstract

ABSTRACKMussles blood (Anadara granosa) is a type of shell that is often consumed by Indonesian community. The shells have non selective feeder and sessile filter that relatively high which mean heavy metal content is found in the shell’s body due to the accumulation of the heavy metals. In an effort to reduce heavy metals in mussles blood, it can be done using the utilization of cassava skin waste. Cassava skin can be used as a material of reducing the heavy metal content of Pb (Lead) in mussles because it contains cellulose that can modify the group to produce hydroxyl which can bind Pb metal ions. This research aimed to analyze the effect of soaking of cassava skin solution (Manihot esculenta Cortex) with decreasing level of heavy metal lead (Pb) on mussles blood (Anadara granosa). This was an experimental research with treatment of cassava skin concentration of 1%, 1.5% and 3% and soaking time 10 minutes, 40 minutes and 80 minutes. The independent variables are concentration of cassava skin solution, soaking time and dependent variable in this research is Pb concentration in mussles blood (Anadara granosa). Samples were analyzed using an Atomic Absorption Spectrophotometer (SSA). The data were analyzed using Kendall's Tau test. The results showed that there was influence of decreasing percentage of heavy metal Pb on soaking time (p <0.05) but did not affect to concentration of cassava skin solution (p> 0.05).
Effect Of Ethanol Concentration In Waru Leaf Extract (Hibiscus Tiliaceus L.) On Lead Levels Of Metal (Pb) Using Atomic Absorption Spectrophotometry Susanti, Maria Mita
Media Farmasi Indonesia Vol. 18 No. 1 (2023): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v18i1.216

Abstract

Waru leaves are able to absorb lead in the air so that it has the potential to accumulate lead. Lead is a heavy metal that is toxic, originating from exhaust gases from motor vehicles and industry. Waru leaves can be used as a traditional medicinal plant by taking the active compounds in extract preparations. The solvent used in the manufacture of the extract is ethanol because it is a polar solvent which can potentially reduce Pb metal which is polar. This study aims to determine the effect of ethanol concentration as a solvent in waru leaf extract (Hibiscus tiliaceus L.) on Pb levels using Atomic Absorption Spectrophotometry (AAS). This research is an experimental research. The independent variable in this study was the variation in ethanol concentration while the dependent variable in this study was Pb levels. The extraction method used was remaceration with 96% ethanol, 70% ethanol and 50% ethanol and the samples were tested quantitatively by atomic absorption spectrophotometry. The lowest lead content in hibiscus leaves was hibiscus leaf extract with 70% ethanol solvent of 0.053 mg/kg. Statistical results using the Oneway ANOVA test obtained a sig value of 0.475 (p>0.05) so that there was no significant effect of variations in the concentration of 50% ethanol, 70% ethanol and 96% ethanol in hibiscus leaf extract on levels of heavy metal Pb.
Effect of Analytical Method on Vitamin C Tablet Levels Stored under Different Temperature Conditions Susanti, Maria Mita
Media Farmasi Indonesia Vol. 19 No. 2 (2024): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v19i2.272

Abstract

Vitamin C tablets are commonly consumed by the public as antioxidant supplements. Vitamin C is highly susceptible to oxidation, which is accelerated by factors such as heat, light, alkali, enzymes, oxidizers, and the presence of copper and iron catalysts. Oxidation will be inhibited if vitamin C is left in an acidic state or at low temperatures. However, many vitamin C tablets are not stored according to recommended conditions due to inadequate temperature control during storage or distribution, leading to changes in their vitamin C levels. Vitamin C levels can be analyzed using the Iodimetry method and UV-Vis spectrophotometry. This study aims to determine the effect of the analysis method on the content of vitamin C tablets stored at various temperature variations. This is an experimental research. The independent variable of this study is the analytical method of determining vitamin C content and the dependent variable of this research is the content of vitamin tablets stored at low temperature (2-6°C), room temperature (27-30°C), and high temperature (48°C). Quantitative analysis of vitamin C levels was conducted using both iodimetry and UV-Vis spectrophotometry methods. The highest vitamin C content was found in the analysis of levels using the UV-Vis spectrophotometry method. Statistical analysis shows significant differences, indicating that the method of analyzing the levels of vitamin C tablets stored under varying temperature conditions affects the levels of vitamin C tablets.