Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Jurnal Kesehatan dan Pembangunan

GAMBARAN KADAR CRP PADA MENCIT ALERGI SETELAH TREATMENT INFUSA DAUN KETEPENG Firmansyah, Adi; I Gede Andika Sukarya; Suryanata Kesuma
Jurnal Kesehatan dan Pembangunan Vol 14 No 1 (2024): Jurnal Kesehatan dan Pembangunan
Publisher : LPPM STIKes Mitra Adiguna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52047/jkp.v14i27.269

Abstract

Allergy is a hypersensitivity reaction that arises due to exposure to allergens. Allergens will bind to IgE attached to mast cells and cause these cells to release various chemicals in the blood. One of them is, histamine which causes most allergic reactions. Allergic reactions can cause inflammation or inflammation. Inflammatory stimulation will later stimulate the release of C-Reactive Protein (CRP). CRP is an inflammatory maker that is produced and synthesized in the liver. Ketepeng leaf infusion has the potential to stimulate an immune response because it contains chemical compounds, namely alkaloids, saponins, flavonoids, tannins, and anthracino. Flavonoids contained in this plant function to provide anti-inflammatory, antiallergic, antioxidant and antifungal effects. The purpose of this study was to determine the effectiveness of ketepeng leaves (Cassia alata L) by examining CRP (C-Reactive Protein) levels in Ovalbumin-allergic mice (Mus musculus). This type of research is Univariate, which is a method for making an overview of the state of the object being examined through data or sampling samples. The results of this study found that in group 2 after being given ovalbumin, CRP levels increased by 181.33 mg/L and in group 3, after being given ketepeng leaf infusion, CRP levels decreased by 48 mg/L. The conclusion of this study is that ketepeng leaf infusion can reduce CRP levels in mice with ovalbumin allergy and there is an effect of increasing CRP levels in mice given ovalbumin of 181.33 mg/L and a decrease in CRP levels after the treatment of ketepeng leaf infusion of 48 mg/L .
Co-Authors . Dahri ACHMAD FAUZI Achmad Fauzi Achrodi, Slamet Agit Kriswantriyono Aisyah , Siti Alfian Umar Karim Alfrian, Taura Philipus Ali Wafa Alya Putri Mulyani Amiarti, Tania Fizhikri Amiruddin Saleh Ana Nur Latifah Andar Lutfi Anna Fatchiya Annisa Azahra Aulia Arrosyiid, Nuur Haadi Asep Saepuloh Aulia Dila Nitami Ayuningtiyas, Rindi Azhar Azhar Dian Masyitha Dwi Sadono Dyah Retna Puspita Elis Fauziyah Erly Yeniska Hermitasari Fadli A Gani Faqih, Achmad Farkha Alfa Centauri Fikri , Adi Wibowo Noor Fitriani Fitriani Fransisca Nada Sherenika Friska Ajeng Lestari Hana Indriana Hardian Hidayatullah, Wahid I Gede Andika Sukarya Indah Irayani Indriana, Hanna Islami, Moh Faza Rijal Izzul Baihaqi Jurnal CARE CARE Kesuma, Suryanata Kusuma, Azzahra Ayutadira Putri Lidya Delimah Pasaribu, Veta Lukmandono Lutfi, Andhar Muhammad Asdar Abdullah Muhammad Saghar Septian Mulyani, Sarah Noor Aisyah Amini Nurfitria Khoirunisa Putri Kinasih Endah Arum Adi Astiti Jati Putri, Dina Amanda Rafael Yoga Widyananta Rafnel Azhari Rahman Indra Kesuma Rasya Khoernunnisa Rasya Khoerunnisa Retna Puspita, Dyah Rindanaung, Marthyn Ruhadi Ruhadi Sahrul Utomo Shofiyah, Binti Siti Syamsiah Siti Syamsiah Slamet Rahayu Suchardy, Randy Zakya Sumardjo Suryadinata, Ningrum Sutandi, Sutandi Sutisna Riyanto Suzuki Syofian Tania Salsabila Nur Rahmah Taufan Abdurrachman Tiara Rahmawati Titania Aulia Tito Wahyu Pradana Tri Herdiawan Apandi Ummu Balqis Utama, Nugraha Priya Wazirul Luthfi Yulia Puspadewi Wulandari Zainuddin Zainuddin Zalianty, Nabiilah Artha Dinda