Retno Gitawati
Puslitbang Farmasi dan Obat Trodisional Badan Litbangkes

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Journal : Jurnal Kefarmasian Indonesia

Analisis Kuantitatif Artemisinin dari Ekstrak Metanol Tanaman Artemisia Annua L. Menggunakan Densitometer Isnawati, Ani; Gitawati, Retno
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 1, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i1.2833

Abstract

Artemisinin is the best antimalaria for chloroquine resistant P. falciparum recommended by WHO in a combination therapy. Artemisinin is isolated from Artemisia annua L (family: Asteraceae) that can grow as it should be in Indonesia and has cult1'vated by BPTO Tawangmangu in order to self-provide for raw material antimalarial. One of the important analysis is method for measuring artemisinin concentration in extract. The method should be more rapid, accurate, and suitable with the instruments available. Measuring analysis are used to determine cultivated result and to analyze cost benefit raw material malaria medicine. The method will also be validated for accuracy, precision, selectivity, sensitivity and linearity. It is found that maximum wave length of artemisinin is 366 nm with TLC-densitometiy validated method, shown a good linearity, a coeficient of corelation of 0.99976, a detection limit of 0.028 mg/mL, and a quantitative limit of 0.094 mg/mL. Artemisinin concentration obtained from methanol extract is 0. 221% with a recovery concentration of 1 01,08%.
Pemanfaatan Pengobat Tradisional oleh Masyarakat Gitawati, Retno
Jurnal Kefarmasian Indonesia VOLUME 1, NOMOR 1, 2009
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v1i1.2836

Abstract

Traditional practitioners Pengobatan Tradisional (Battra) are becoming parts of health care services, and are used to overcome certain health problems in rural areas as well as in urban. However, there is not enough nation wide data of how wide are traditional practices being utilized by the population. Further analysis using the nationwide Riskedas-2007 data is conducted to describe how Battra in Indonesia involved in the population's health care. The analysis is done descriptively, using the cleaned Kesmas (public health) data, ana crosssectional designed with the total sample size of 36.584 respondents. The results showea 1.2% of respondents rely on Battra for inpatient and outpatient services. About 10.1% respondents in West Sulawesi province went to in-patient-serviced (hospitalized) Battra jot their health problems, which is the largest proportion among other Battra utilizations in other provinces. While South Kalimantan is the province with the largest proportion of respondents (4. 7%) went to outpatient services of Battra. Access to the nearest conventional/allopalhic health care services (e.g. public hospital, primary health care, clinics) infuenced the respondent ’s preference for going to Battra The proportion of male respondents who went to Battra is greater than the females, and so the lower educated, and the lower economic status of respondents. More respondents in rural areas went to Battra compared to those in urban.
Kerasionalan Penggunaan Obat Diare yang Disimpan di Rumah Tangga di Indonesia Raini, Mariana; Gitawati, Retno; Rooslamiati, Indri
Jurnal Kefarmasian Indonesia VOLUME 5, NOMOR 1, FEBRUARI 2015
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v5i1.3473

Abstract

Diarrhea is a major health problem in developing countries. WHO data showed diarrhea caused the death of 2.5 million people, 80% are children under five years old. Riskesdas 2013 stated the prevalence of diarrhea in Indonesia is 7%, whereas 12.2% of it are children under five years old. Self-medication is common and access for the medicine is easy. This analysis aims to assess the rational use of diarrhea medication stored in households. The rational drug used is associated with the mother's education level and household ownership quintile. This study design is cross sectional. The data was taken from Riskesdas 2013 namely type of medicines (data from block VI), mother’s education level data (from block IV) and economic status presented as household ownership quintile level (data from block IX). The result showed that the highest percentage of diarrhea drugs stored at household is adsorbents (40.4%), followed by antibiotic (22.4%) and traditional medicine (18.5%). Rationality of diarrhea medications stored in households is 74.7% and irrational (25.3)%). Wealthy people (quintiles 4 and 5) are 2.019 times more rational compared with the poor (quintiles 1, 2 and 3), while mothers with a good education (high school and above) are 1.944 times more rational in using medicine for diarrhea treatment compared with mothers with low education (below high school).
Penggunaan Jamu pada Pasien Hiperlipidemia Berdasarkan Data Rekam Medik, di Beberapa Fasilitas Pelayanan Kesehatan di Indonesia Gitawati, Retno; Widowati, Lucie
Jurnal Kefarmasian Indonesia VOLUME 5, NOMOR 1, FEBRUARI 2015
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v5i1.3474

Abstract

Hyperlipidemias are disorders which are manifested by elevation of blood lipid, such as total cholesterol and/or triglyceride above the normal level. Hyperlipidemia management is done by lifestyle modification (high-fiber diet, exercises) as well as using antidyslipidemias. On the other hand, non-conventional or traditional treatment of hyperlipidemias using herbals (jamu) is becoming ubiquitous, performed by jamu practitioner clinician (dokter praktik jamu). This study is a part of a web-site Jamu Registry Study, which is intended to figure herbal (jamu) dispensed by jamu practitioner clinician for hyperlipidemic patients. A descriptive, cross-sectional design is applied, using medical record data of ‘jamu’ patients from some health facilities, in 7 provinces in Indonesia. Results showed, out of 97 hyperlipidemic patients were mostly female (60.8%), aged 48-58 years (46.4%); most of them (62.9%) were treated merely with jamu for 1 – 2 weeks, and the rests were treated with jamu in combination with conventional and/or other alternative medication. The most jamu used were branded herbal capsules (55.7%) containing of Guazumae folium and Murrayae folium. Adverse events were reported in four cases i.e. diarrhea and diuresis
Pola Peresepan Anak dengan Infeksi Saluran Pernapasan Akut (ISPA) Non Pneumonia di Klinik Handayani, Rini Sasanti; Sari, Ida Diana; Prihartini, Nita; Yuniar, Yuyun; Gitawati, Retno
Jurnal Kefarmasian Indonesia VOLUME 11, NOMOR 2, AGUSTUS 2021
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v11i2.4734

Abstract

Acute respiratory infection (ARI) is a common disease in the community. Riskesdas 2018 stated that ARI prevalence was 4.4% and the highest was in 1-4 years old children (8%). The capitation payment system in clinics collaborated with BPJS Kesehatan demands the physician to prescribe as effective and as efficient as possible. On the other hand, the capitation tariff obtained by clinics is considered as too low, thus constrains of the prescription leading to irrational prescribing is likely to occur. This study analyses further the prescribing pattern for ARI children in clinics and its rationality based on the difference in source of funding. A cross sectional research using retrospective method was conducted. Data were gathered from 409 medical records and or patients’ prescription of children between 1-12 years old and diagnosed as having non pneumonia ARI during 1st January to 30th November 2019. Result showed that non pneumonia ARI patients were mostly boys (54,3%) aged 1-5 years old (6.0%). The average number of items for BPJS patients was 3,45, the percentage of generic prescribing was twofold higher for BPJS group (63.94%), the percentage of essential medicine prescribing was 63.96% while the percentage of antibiotic use was lower (48.50%). Dosage propriety for BPJS patients was 70.80% which was slightly higher than non-BPJS group. Overall, the prescribing indicators and dosage properness for BPJS patients were better than non-BPJS patients.