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All Journal Pendidikan Ekonomi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Poltekita : Jurnal Ilmu Kesehatan Jaringan Laboratorium Medis Borneo Journal of Medical Laboratory Technology Journal SAGO Gizi dan Kesehatan Poltekita: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Pengabdian Masyarakat Bidang Kesehatan Journal of Development Education and Learning
Dina Afrianti1
Program Studi Teknologi Bank Darah, Jurusan Analis Kesehatan, Politeknik Kesehatan Kemenkes Semarang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Poltekita : Jurnal Ilmu Kesehatan

 1 
Screening for the Detection of IgG anti-Toxoplasma gondii Antibodies in Female Donors at Semarang Regency Afrianti, Dina; Putri, Adita Puspitasari Swastya; Wikandari, Ririh Jatmi; Wahyudi, Wahyudi
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.2862

Abstract

Toxoplasmosis is a widespread zoonotic disease caused by Toxoplasma gondii (T.gondii). Blood and blood products are possible routes of transmission of T. gondii, especially in patients who have undergone multiple transfusions. The aim of this study is to determine the seroprevalence of toxoplasmosis in female donors using blood serum which is analyzed serologically to detect ImmunoglobulinG (IgG) using the Enzyme-Linked Fluorescent Assay (ELFA) method, as well as the relationship between risk factors for toxoplasmosis, such as keeping cats, receiving blood transfusions, eating undercooked meat and eating raw vegetables. This research is an analytic observational study using a cross-sectional study design. The sample taken is female donor candidates who are willing to participate during the study period, from March to September 2023, and have met the inclusion criteria to become research subjects by explaining the purpose and procedure of the study and the consent letter signed by each research subject before blood samples were taken and filling out the research questionnaire. 177 blood serum samples of female donors were collected from blood donor candidates using consecutive sampling method and a questionnaire to obtain risk factor data that influence the incidence of toxoplasmosis. The results showed that the seroprevalence of toxoplasmosis in the blood of female donor at Indonesian Red Cross Blood Donor Unit (UDD PMI) Semarang Regency, Central Java Province was 26.6%. In this study the risk factors that influence the incidence of toxoplasmosis are consuming raw vegetables with 5.835 times more risk than women who do not consume raw vegetables, while other factors such as keeping cats, receiving blood transfusions, and eating undercooked meat, have no significant effect. The seroprevalence of toxoplasmosis in female donors at UDD PMI of Semarang Regency is quite high due to the habit of eating raw vegetables or fresh vegetables with a very high transmission potential.
Sungkai Leaf Extract (Peronema canescens Jack) Reduces MDA Levels and Increases IL-10 Levels in MSG-Induced Wistar Rats Wahyudi, Wahyudi; Chodijah, Chodijah; Sumarawati, Titiek; Afrianti, Dina
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 3 (2023): November
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i3.3015

Abstract

The addition of Monosodium Glutamate (MSG) to ready-to-eat food can change eating habits, coupled with a lack of activity which can have an impact on health. MSG as a trigger for increased reactive oxygen species (ROS), causing systemic damage, the impact of excessive MSG consumption can be reduced by modifying the diet to contain high sources of antioxidants. Sungkai leaf extract can be an alternative as a natural antioxidant. Sungkai leaf extract antioxidants are expected to neutralize ROS thereby repairing cell damage. Objective: This study aims to determine how giving sungkai leaf extract affects MDA and IL-10 levels in MSG-induced mice. Method: Experimental research with a Randomized Post test only control group design. The total sample was 24 male Wistar rats divided into 4 groups. KN healthy mice, K(-) were given 1g MSG/rat, P1 was given 1g MSG/rat and 28mg sungkai leaf extract/rat, P2 was given 1g MSG/rat and 56mg sungkai leaf extract/rat. Results: The average results showed a decrease in MDA levels and an increase in IL-10 levels after treatment for 21 days, the One way Anova test followed by Post hoc LSD showed that each treatment group was significantly different from the control group where the MDA level in group P2 was 0, 07mg/ml ± 0.01 experienced a significant decrease compared to the KN group 0.07mg/ml ± 0.01 while IL-10 levels experienced a significant increase in the P1 group 130.10pg/ml ± 13.29 when compared to the KN group 60.43pg/ml ±17.40. Conclusion: Sungkai leaf extract (Penonema Canescens Jack) was able to reduce MDA levels at a dose of 56 mg/mouse in mice injected with 1gr MSG/rat and experienced a significant increase in IL-10 levels with a dose of 28 mg sungkai leaf extract/rat injected with 1gr MSG/rat.
Evaluation of Toxoplasmosis in Female College Students Wikandari, Ririh Jatmi; Afriansya, Roni; Kuncara, Rachmad Bayu; Afrianti, Dina; Setyowatiningsih, Lilik
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 4 (2024): February
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i4.3209

Abstract

Female students are a group of women of childbearing age who can become pregnant and have risk factors for toxoplasmosis which can cause pregnancy disorders, birth defects, and death. Seroepidemiological studies of toxoplasmosis in women are essential to determine whether infection occurs in the early stages of fertilization or earlier. The research aimed to determine the incidence of toxoplasmosis in female college students. This research was carried out in June 2023 and has received ethical recommendations from KEPK Poltekkes Kemenkes Semarang. The type of research used was analytical descriptive. Sampling used purposive sampling. The inclusion criteria were 87 students who were willing to have their blood taken. Blood is taken using the venipuncture method, then the whole blood is separated from the plasma. Plasma samples were collected and analyzed for the presence of anti-Toxoplasma gondii using the ELISA method. Then the data was analyzed using SPSS software, univariate analysis to determine the frequency distribution and percentage of each variable. The results showed that 31 students were positive for IgG anti-Toxoplasma gondii. Of these, the majority aged 20 years (n = 20, 16.1%) were positive for anti-Toxoplasma gondii IgG. Toxoplasmosis infection of 9.2% occurred in female college students who owned cats, 3.4% occurred in female college students who consumed undercooked meat, and 29.8% of female college students who consumed raw vegetables. Female college students have risk factors for Toxoplasma gondii infection so it is important to carry out screening so that Toxoplasma gondii can be detected and treated immediately.
Co-Authors Adita Puspitasari Swastya Putri Adita Puspitasari Swastya Putri Aminahtun Latifah Anggraini, Maysita Ari CHODIJAH, CHODIJAH Citra Ramayan Desi Areva Dewi Kurniasih Dewi Kurniasih Djoko Priyatno, Djoko Duri, Iin Desmiany Eko Naning Sofyanita Elis Susilawati Kuncara, Rachmad Bayu Latifah, Aminahtun Mufti, Meyda Fianisa Muslina Muslina Muslina Muslina, Muslina Negoro, Muhamad Syamsul Arif Setiyo Nurul Qomariyah Putri, Adita Puspitasari Swastya Rachmad Bayu Kuncara Rahmadhani, Afiffah Gita Ririh Jatmi Wikandari Rodhi Hartono Roni Afriansya Setyowatiningsih, Lilik Sofyanita, Eko Naning Surati Surati Susilawati, Elis Swastya Putri, Adita Puspitasari Teguh Budiharjo, Teguh Titiek Sumarawati WAHYUDI Wahyudi Wahyudi Wahyudi Wahyudi Widodo Widodo