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Journal : Indonesian Journal of Statistics and Its Applications

PENINGKATAN AKURASI KLASIFIKASI INTERAKSI FARMAKODINAMIK OBAT BERBASIS SELEKSI PASANGAN OBAT TAKBERINTERAKSI Hilma Mutiara Winata; Farit Mochamad Afendi; Anwar Fitrianto
Indonesian Journal of Statistics and Applications Vol 3 No 3 (2019)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v3i3.327

Abstract

Identifying the pharmacodynamics drug-drug interaction (PD DDI) is needed since it can cause side effects to patients. There are two measurements of drug interaction performance, namely the golden standard positive (GSP) which is the drug pairs that interact pharmacodynamics and golden standard negative (GSN), which is a drug pairs that do not interact. The selection of GSN in the previous which studies were only selected randomly from a list of drug pairs that do not interact. The random selection is feared to contain drug pairs that actually interact but have not been recorded. Therefore, in this study the determination of GSN was carried out by, first, grouping drug pairs included in the GSP using the DP-Clus algorithm with certain values of density and cluster properties. Then the drugs in different group would be paired and only the drug pairs in the GSN list are selected. It was found that our new proposed classification method increases the AUC value compared to the results obtained by random selection of GSN.
PERBANDINGAN BEBERAPA METODE KLASIFIKASI DALAM MEMPREDIKSI INTERAKSI FARMAKODINAMIK Hasnita Hasnita; Farit Mochamad Afendi; Anwar Fitrianto
Indonesian Journal of Statistics and Applications Vol 4 No 1 (2020)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v4i1.328

Abstract

One mechanism for Drug-Drug Interaction (DDI) is pharmacodynamic (PD) interactions. They are interactions by which the effects of a drug are changed by other drugs at the site of receptor. The interactions can be predicted based on Side Effects Similarity (SES), Chemical Similarity (CS) and Target Protein Connectedness (TPC). This study aims to find the best classification technique by first applying the scaling process, variable interaction, discretization and resampling technique. We used Random Forest, Support Vector Machines (SVM) and Binary Logistic Regression for the classification. Out the three classification methods, we found the SVM classification method produces the highest Area Under Cover (AUC) value compared to the other, which is 67.91%.
HUBUNGAN AKREDITASI DAN UJIAN NASIONAL PADA SEKOLAH NEGERI DENGAN GENERALIZED STRUCTURED COMPONENT ANALYSIS Rezi Wahyuni; Budi Susetyo; Anwar Fitrianto
Indonesian Journal of Statistics and Applications Vol 3 No 3 (2019)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v3i3.342

Abstract

There are several views and tendencies that distinguish between schools and madrasas in several aspects, one of them is the curriculum. Madrasah as islamic educational institution contains more religious lessons compared to public schools. As a result, madrasah are considered less able to provide good result in educational achievement. Overall, the education system which is based on National Education Standards (SNP) is used for assessing the educational accreditation. SNP is the minimum criterion of education system in Indonesia can be evaluated from the National Examination (UN). As latent variable, SNP is measured through 124 items as variable indicators. One of methods which is used to measure the relationship among latent variables, and latent variables with their indicator variables is structural equation modeling (SEM). A component-based SEM is called Generalized Structured Component Analysis (GSCA). GSCA analysis based on measurement model, there were 9 indicators were not significant, in which 1 indicator of standard of education and staff (SPT), 5 indicators on standard of infrastructure (SSP), and 3 indicators on standard of cost (SB). Evaluation of the structural model, it was found that the path coefficient of standard of content (SI) to UN was not significant and standard of competency (SKL) given the biggest direct effect to UN. The overall goodness of fit model showed that the total variance that can be explained of all indicators and latent variables in evaluating model of accreditation and national examinations was 63.9%. The difference in the percentage of accreditation status between schools and madrasas shows different UN results. In the 2017-2018 period, MTsN had a higher percentage of accredited schools, in line with that the average MTsN UN obtained was better than that of SMP in all types of subjects.
PERBANDINGAN MODEL GARCH SIMETRIS DAN ASIMETRIS PADA DATA KURS HARIAN Isna Shofia Mubarokah; Anwar Fitrianto; Farit M Affendi
Indonesian Journal of Statistics and Applications Vol 4 No 4 (2020)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v4i4.709

Abstract

ARCH and GARCH models are widely used in financial data to describe its volatility pattern. The models assume the positive and negative return residual gives the same or symmetric influence on its volatility. However, in reality, this assumption is frequently violated, which is called heteroscedasticity. Therefore, to deal with heteroscedasticity and asymmetric data, the asymmetric GARCH models, which are EGARCH and GJR-GARCH models are used. This research aims to compare the models between symmetric and asymmetric GARCH to make financial data modeling. It uses daily data on three foreign exchange rates for IDR including IDR/CNY, IDR/JPY, and IDR/USD. The data series to be used here are from January 4, 2016, to January 20, 2020. This research method is started by selecting the best mean model for each data. Based on the best mean model, then modeling the mean and variance function are simultaneously conducted using the GARCH model. To test whether there was an asymmetric effect on the data, a Lagrange multiplier test was applied on the residuals of the GARCH model. The results show that the asymmetric effect was found in the IDR/CNY and IDR/JPY exchange rates. To overcome this asymmetric effect, EGARCH and GJR-GARCH model were applied to the two exchange rates. Then the two models are compared to find out which volatility model is better. Using AIC and BIC we find EGARCH as the best model for IDR/CNY exchange rates daily return and GJR-GARCH as the best model for IDR/JPY exchange rates daily return.
Identification Pharmacodynamic Interactions of Active Compounds of Diabetes Mellitus Type 2 Herbal Plants Using the Random Forest Method: Identifikasi Interaksi Farmakodinamik Senyawa Aktif Tanaman Jamu Diabetes Melitus Tipe 2 Menggunakan Metode Random Forest M. Aiman Askari; Farit M. Afendi; Anwar Fitrianto; Sony Hartono Wijaya
Indonesian Journal of Statistics and Applications Vol 6 No 2 (2022)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v6i2p245-260

Abstract

Drug-drug interactions is defined as the modification of the effect of a drug as a result of another drug given simultaneously or with an interval or when two or more drugs interact so that the effectiveness or toxicity of one or more drugs changes. Pharmacodynamic interactions are one type of interaction that needs special attention because these interactions work directly on the body's physiological systems and compete on the same receptors so that they can be antagonistic, additive, or synergistic. The use of medicinal plants is becoming an alternative because in addition to their relatively safer side effects, medicinal plants consisting of active compounds are appropriate in treating degenerative metabolic diseases triggered by mutations in many genes. As in the case of polypharmacies, interactions of active compounds in medicinal plants can also lead to phapharmodynamic interactions. Therefore, it is also necessary to identify the active compounds so that it can then be known whether the interaction of the compounds will be beneficial or detrimental. In this study, pharmacodynamic identification was applied to Diabetes Mellitus Type 2 medicinal plant compounds by using the independent variables Target Protein Connectedness (TPC), Side Effect Similarity (SES), and Chemical Similarities (CS) using Random Forest classification method. From a search of various databases, 21 active compounds were obtained and then only 100 compound interactions could be calculated as independent variables. With an accuracy value and AUC of 0,96, there were 93 pairs of compounds that interacted pharmacodynamically and the remaining 7 did not interact.
Sentiment Analysis of Twitter Users’ Opinion Towards Face-to-Face Learning: Analisis Sentimen Tanggapan Masyarakat Pengguna Twitter terhadap Pembelajaran Tatap Muka Silmi Annisa Rizki Manaf; Aam Alamudi; Anwar Fitrianto
Indonesian Journal of Statistics and Applications Vol 7 No 1 (2023)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v7i1p15-31

Abstract

In early 2022, the government allowed face-to-face learning again after approximately one year of online learning. When face-to-face learning will be held again in several areas, the number of Covid-19 has increased and the government has imposed the enforcement of restrictions on community activities. The pros and cons of face-to-face learning also occur on social media, one of them is on Twitter. This study used twitter data for January 30th – February 7th 2022. Opinions on twitter regarding face-to-face learning were studied by sentiment analysis using the binary logistic regression method with sentiment classes being positive and negative. Labeling uses based on the final score of the difference between the number of positive and negative words. The purpose of this study is to determine the public’s perception of the policy of implementing face-to-face learning in the era of the Covid-19 on social media especially Twitter. From this study, public’s perception tends to be in a negative direction which indicates that they have not agreed enough with the existence of face-to-face learning in the period of February 2022 with the accuracy was 85%, sensitivity was 77%, specificity was 88%, and AUC was 91%.
Comparison Between SARIMA and DeepAR with Optuna Hyperparameter Optimization for Estimating Rice Production Data in Indonesia Muhammad Farhan Zahid; Anwar Fitrianto; Pika Silvianti; Aam Alamudi
Indonesian Journal of Statistics and Applications Vol 8 No 2 (2024)
Publisher : Departemen Statistika, IPB University dengan Forum Perguruan Tinggi Statistika (FORSTAT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/ijsa.v8i2p95-111

Abstract

Forecast is a prediction of future events that had taken a significant role in our society especially when facing time-sensitive issues like food availability. Food is a critical aspect in ensuring people's welfare, especially in a country like Indonesia with a large population. Availability and access to rice are a vital need for the people of Indonesia. Rice is not only the main source of carbohydrates, but also has a central role in the cultural and social aspects of Indonesian society. Forecasting can be a strategy to anticipate fluctuations in food demand and supply. Forecasting can be an important instrument for the government and stakeholders to make the right and effective decisions. The growing period of rice which is heavily influenced by seasonality makes DeepAR and SARIMA techniques a good solution to solve this problem. Both methods offer the ability to address features in rice production such as trends, seasonality, and anomaly effects. This study demonstrates that DeepAR, especially when optimized with Optuna, outperforms SARIMA in forecasting rice production in Indonesia, as evidenced by superior performance in key evaluation metrics such as Root Mean Square Error (RMSE) and Mean Absolute Percentage Error (MAPE).
Co-Authors A. A., Muftih Aam Alamudi Abd. Rahman Adeline Vinda Septiani Agung Tri Utomo Agus M Soleh Agus Mohamad Soleh Ahmad Syauqi Alfa Nugraha Alfa Nugraha Pradana Alfa Nugraha Pradana Alfa Nugraha Pradana Alfa Nugraha Pradana Alfi Indah Nurrizqi Aliu, Mufthi Alwi ALIU, MUFTIH ALWI Amalia Kholifatunnisa Amanda, Nabila Amatullah, Fida Fariha Amelia, Reni Amir Abduljabbar Dalimunthe Anadra, Rahmi Anang Kurnia Anang Kurnia Anik Djuraidah Anisa Nurizki Annisa Putri Utami Annissa Nur Fitria Fathina Ardhani, Rizky Aristawidya, Rafika Asri Pratiwi, Asri Assyifa Lala Pratiwi Hamid Azis, Tukhfatur Rizmah Aziza, Vivin Nur Bagus Sartono Budi Susetyo Budi Susetyo Budi Susetyo Budi Susetyo Bukhari, Ari Shobri Cahya Alkahfi Daswati, Oktaviyani Defri Ramadhan Ismana Deri Siswara Dessy Rotua Natalina Siahaan Dessy Siahaan Devi Permata Sari Dian Handayani Dwi Jumansyah, L.M. Risman Erfiani Erfiani Erfiani Erfiani Erfiani Erfiani Erfiani Erfiani Erfiani Erfiani Fadilah, Anggita Rizky Fajar Athallah Yusuf Farit M Affendi Farit M. Afendi Farit Mochamad Afendi Fatimah Fatimah Fauziah, Monica Rahma Fulazzaky, Tahira Ghina Fauziah Gustiara, Dela Hari Wijayanto Harismahyanti A., Andi Hasnataeni, Yunia Hasnita Hasnita Heri Cahyono I Made Sumertajaya Ilham Azagi Ilmani, Erdanisa Aghnia Imam Hanafi Indah, Yunna Mentari Indahwati Indahwati Indahwati Indahwati, Indahwati Irsyifa Mayzela Afnan Irzaman, Irzaman Ismah, Ismah Isna Shofia Mubarokah Iswan Achlan Setiawan Iswati Jamaluddin Rabbani Harahap Jap Ee Jia Jia, Jap Ee Jumansyah, L. M. Risman Dwi Jumansyah, L.M. Risman Dwi Khairil Anwar Notodiputro Khikmah, Khusnia Nurul Khusnia N. K. Khusnia Nurul Khikmah Kriswan, Suliana Kusman Sadik L.M. Risman Dwi Jumansyah L.M. Risman Dwi Jumansyah La Ode Abdul Rahman La Ode Abdul Rahman Lai Ming Choon Linganathan, Punitha lmam Hanafi M. Aiman Askari M.S, Erfiani Marshelle, Sean Megawati Megawati Mohamad Solehudin Zaenal Muftih Alwi Aliu Muftih Alwi Aliu Muhadi, Rizqi Annafi Muhammad Farhan Zahid Muhammad Irfan Hanifiandi Kurnia mutiah, siti Nabila Ghoni Trisno Hidayatulloh Nadira Nisa Alwani Nafisa Berliana Indah Pratiwi Nashir, Husnun Nisa Nur Aisyah Novi Hidayat Pusponegoro Nugraha, Adhiyatma Nur Hidayah Nur Khamidah Pangestika, Dhita Elsha Pika Silvianti Pika Silvianti Pradnya Sri Rahayu Punitha Linganathan Putri Auliana Rifqi Mukhlashin Putri, Oktaviani Aisyah Rachmat Bintang Yudhianto Rafika Aufa Hasibuan Rahmatun Nisa, Rahmatun Rais Reka Agustia Astari Reni Amelia Reni Amelia Retna Nurwulan Riansyah, Boy Rifda Nida’ul Labibah Riska Yulianti, Riska Rizki Manaf, Silmi Anisa Rizki, Akbar Rizqi, Tasya Anisah Sachnaz Desta Oktarin salsa bila Seta Baehera Setyowati, Silfiana Lis Siau Hui Mah Siau Man Mah Silmi Annisa Rizki Manaf Silmi Annisa Rizki Manaf Siregar, Indra Rivaldi Siti Hafsah Siti Hasanah Siti Nur Azizah, Siti Nur Sofia Octaviana Sony Hartono Wijaya Suantari, Ni Gusti Ayu Putu Puteri Suliana Kriswan Tahira Fulazzaky Titin Agustina Titin Yuniarty Yuniarty Uswatun Hasanah Utami Dyah Syafitri Vitona, Desi Vivin Nur Aziza Waliulu, Megawati Zein Wan Muhamad, Wan Zuki Azman Wan Zuki Azman Wan Muhamad Wan Zuki Azman Wan Muhamad Wan Zuki Azman Wan Muhamad Wan Zuki Azman Wan Muhamad Waode, Yully Sofyah Winata, Hilma Mutiara Xin, Sim Hui Yenni Angraini Yuniarsyih R.A, Rizqi Dwi Zein Rizky Santoso