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All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Sibermas (Sinergi Pemberdayaan Masyarakat) Indonesian Journal of Pharmaceutical Education Jurnal Kolaboratif Sains Jurnal Ilmiah Bakti Farmasi Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Jurnal Kesehatan Farmasi Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK) Journal of Community and Clinical Pharmacy Journal of Pharmacology and Natural Products
Hiola, Faramita
Universitas Negeri Gorontalo
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Journal : Indonesian Journal of Pharmaceutical Education

 1 
Karakterisasi Senyawa Minyak Atsiri Ekstrak Etil Asetat Bawang Putih (allium sativum l.) Taupik, Muhammad; Andy Suryadi, A. Mu’thi; Hiola, Faramita; Rannu, Jumriani
Indonesian Journal of Pharmaceutical Education Vol 1, No 2 (2021): Mei-Agustus 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i2.11767

Abstract

Garlic (Allium sativum L.) is one of tuber vegetable crops that is widely grown in various countries in the word and is often used as food spices and medicines. The purpose of this study was to characterize the volatile oil compound ethyl acetate extract of garlic (Allium sativum L.) using Uv-Vis and IR spectrophotometric metods. Several methods used in this research included extraction, identification of compounds, fractionation, thin layer chromatography, prepative thin layer chromatography, and characterization of compounds using Uv-Vis spectrophotometry and IR spectrophotometry. A total of 3000 grams od garlic was macerated using 70% ethanol, then evaporated and obtained a thick extract of 421.5 grams. The results of thin layer chromatography used an eluent ratio of Methanol : Ethyl Acetate (4:2) obtained stains with an Rf value of 0,55. The optimizion result of maximum wavelength of garlic isolated (Allium sativum L.) is 232 nm wich indicated  the presence of an electron transition  n→σ*.The results of IR  spectrophotometry had fuctional groups at wave numbers 3231.530 cm-1 (N-H), 1637.48 cm-1 (C=O), 1014.65 cm-1(C-N). 
Interaksi Obat Pada Pasien Diabetes Melitus Tipe 2 Dengan Penyakit Penyerta Di Rumah Sakit Otanaha Kota Gorontalo Rasdianah, Nur; Hiola, Faramita; Andy Suryadi, A. Mu’thi; Gani, Athira Sri Wahyuni
Indonesian Journal of Pharmaceutical Education Vol 1, No 1 (2021): Januari-April 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i1.9953

Abstract

As the numbers of cases continue to soar, diabetes mellitus or DM is one the most common disease in Indonesia. The WHO predicts that in 2030, numbers of diabetics in Indonesia will rise up to 21.3 million people, compared to 8.4 million people in 2000. Regarding the treatment, most of diabetes cases are commonly treated with pharmacological therapy. In this regard, polypharmacy and medications-related problems might occur during the treatment to control blood glucose level that is concurrent with the treatment of other diseases. Drug Interaction is a common medication-related problem. The present study is aimed to investigate the cases of drug interaction in patients with type-2 DM with comorbid diseases during the period of January-December 2019 in Otanaha Hospital, Gorontalo. As based on the inclusion criteria, the study involved 92 patients with type-2 DM and comorbid disease involved combination of metformin-glimepiride (47%), insulin (19%), metformin (14%), and glimepiride (9%). Moreover, based on the observation, minor interaction occurred the most (47%), followed by moderat interaction (31%) and major interaction. To sum up, the cases of drug interaction in patients with type-2 DM and comorbid disease in Otanaha Hospital, Gorontalo are relatively high. It is further concluded that the pharmacist's role is influential to supervise and monitor the patients medication intake.
Formulasi Sediaan Emulgel Ekstrak Daun Kelor (Moringa oleifera Lam) Dan Uji Aktivitas Antioksidan Menggunakan Metode DPPh Nurrohwinta Djuwarno, Endah; Hiola, Faramita; Isa, Ishak
Indonesian Journal of Pharmaceutical Education Vol 1, No 1 (2021): Januari-April 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i1.9947

Abstract

Moringa (Moringa oleifera Lam) is one of the plants that has high antioxidant activity, especially in the leaves. Emulgel is one of the topical dosage which dermatologically has several beneficial properties, namely thixotropic, not oily, easy to spread, easy to clean, soft, easy to wash, long lasting, transparent and comfortable when used. The purpose of this research was to formulate moringa (Moringa oleifera Lam) leaves extract into emulgel dosage forms and determine the antioxidant activity of the dosage using DPPH method.The research began with extraction of moringa leaves and optimization of the base by varying the concentration of carbopol 940 as gelling consisting of F1 0.5%, F2 1%, F3 1.5% and F4 2%. The base that met the requirements of good physical stability was F2.  The F2 base was then made into emulgel dosage with 3 concentration variations of the extract, namely F2a 4%, F2b 5% and F2c 6%. The physical stability test result of each formula met the organoleptic test,the pH test, the dispersion test, the adhesion test, the viscosity test, and the freeze-thaw test. The One way ANOVA statistical test result showed that the p value was greater than 0.05, which meant that the emulgel dosage had good physical stability. The IC50values of each antioxidant activity result were F2a (t0 = 120.464 g/mL; t28 = 144.887 g/mL), F2b (t0 = 113.642 g/mL; t28 = 128.407g/mL), F2c (t0 = 74.745 g/mL; t28 = 90.618 g/mL). The statistical results of the t-test showed thep value = 0,027, (less than 0.05), This indicated that there were significant difference results of the antioxidant activity test between the three formulas on the first day (t0) and on the 28th day (t28).
Co-Authors A. Mu’thi Andy Suryadi Akuba, Juliyanti Andy Suryadi, A. Mu’thi Anggai, Rifka Anggraini Ariani H. Hutuba Ayu Maloho, Sity Nur Rahayu Maloho Dewa Ayu Puspita Divia Handayani Mudjidu Dr. Apt. Hamsidar Hasan S.Si.,M.Si Endah Nurrohwinta Djuwarno Fika Nuzul Ramadhani Gani, Athira Sri Wahyuni Goni, Latifa Gunawan, Selvi Ayu Setiaarini Halada, Ichlasul Oktofandi Hamsidar Hasan Hamzah, Alifiah Ramawaty Hasrita Samudi Hutuba, Ariani H Iman, Devansyah Ishak Isa Ismail, Delvita Ismail, Ulfatul Magfirah M. Julianty Akuba Kahar, Putri Kartika Adhilia Katili, Ayub H. Lahay, Astiara Lia Amalia LIA AMALIA Liputo, Kartika Vany Madania, Madania Madania, Madania Mahdalena Sy Pakaya mahdalena sy. pakaya Makkulawu, Andi Mangulu, Anindia Mohamad Aprianto Paneo Muhammad Taupik Muhammad Taupik Nanang R. Paramata Nanang Roswita Paramata Nur Ain Thomas Nur Rasdianah Pakaya, Meri Isriani Papeo, Dizky Ramadani Putri Paputungan, Jihan Utari Puluhulawa, Lisa Efriani Putri Ayuningtias Mahdang Putri Ayuningtias Mahdang Rannu, Jumriani Robert Tungadi Salamanya, Ahmad Hayun Samsi, Khairun nisha Selong, Siti Ruwaida D. Sri Nur'ain E. Ahmad Suleman, Ahmad Teti Sutriyati Tuloli Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Yasir Mokodompis