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All Journal Jurnal Farmasi Udayana Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi Indonesia Poltekita: Jurnal Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
Dina Yuspitasari
Akademi Farmasi Yarsi Pontianak
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Journal : Jurnal Farmasi Udayana

 1 
Penentuan Kadar Flavonoid Total Ekstrak Etanol Jamur Susu Harimau (Lignosus rhinocerus) Dina Yuspita Sari; Widyasari R; Taslima AN
Jurnal Farmasi Udayana Vol. 10, No 1, Tahun 2021
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2021.v10.i01.p03

Abstract

ABSTRAK Jamur susu harimau (Lignosus rhinocerus) merupakan tanaman yang digunakan dalam pengobatan tradisional di pedalaman Kalimantan Barat terutama di Kapuas Hulu. Salah satu konstituen fitokimia yang terkandung adalah flavonoid (flavon dan flavanon). Penelitian ini bertujuan untuk menentukan kadar flavonoid total pada ekstrak etanol jamur susu harimau. Simplisia jamur susu harimau dimaserasi menggunakan etanol 96 %. Skrining fitokima terhadap keberadaan flavonoid dalam ekstrak menggunakan serbuk magnesium dan amil alkohol. Penentuan kadar flavonoid total pada ekstrak etanol jamur susu harimau dilakukan secara spektrofotometri UV-Vis dengan metode kolorimetri (AlCl3) pada ? 410 nm dan dinyatakan sebagai flavonoid total dalam ekuivalen kuersetin (EQ). Kadar flavonoid total pada ekstrak etanol jamur susu harimau adalah sebesar 33,041 mgEQ/g ekstrak. Ekstrak etanol jamur susu harimau yang mengandung flavonoid berpotensi sebagai sumber antiooksidan alami dan potensial untuk dikembangkan dalam produk obat dan kosmetik. Kata kunci: Jamur susu harimau, kadar flavonoid total, kolorimetri.
Keamanan Hair Tonic Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol dari Kayu Secang (Caesalpinia sappan L.) dengan Metode Uji Iritasi Primer dan HET-CAM Dina Yuspita Sari; Ika Ristia Rahman
Jurnal Farmasi Udayana Vol. 10, No 2, Tahun 2021
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2021.v10.i02.p08

Abstract

Hair tonic is a hair care cosmetic to reduce hair loss, stimulate, and increase hair volume. Secang wood (Caesalpinia sappan L.) has the potential to be developed as an active substance in hair tonic products because it contains flavonoids, polyphenols, including brazilin which are used to treat damage hair. To ensure the safety of hair tonic products, safety tests are required, including skin and eye irritation tests. This study aims to determine the safety of hair tonic formula of ethanol extract, ethanol fraction, and chloroform-methanol fraction from sappan wood. Ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappan wood were formulated into hair tonic preparations. The hair tonic safety test includes: primary irritation test and eye irritation test using HET-CAM method. Based on the primary irritation test, the score of erythema and edema on the skin obtained a PII value of 0 (non-irritating category). The HET-CAM test on the three hair tonic formulas, positive control and negative control, showed that the positive control (lactic acid) resulted in an irritation score of 9.51 (strong irritation category); negative control (NaCl 0.9%) and the three hair tonic formulas had an irritation score of 0 (no irritation category). This indicates that the hair tonic formula from ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappanwood is not irritating and safe to use. Keywords: HET-CAM, primary irritation test, sappan wood
Co-Authors Athiah Masykuroh Dian Kartikasari Fadli Fadli Lindasari . Puspita, Weni Rahman, Ika Ristia Ratna Widyasari Rosi Cahayuni Wahida Taslima AN Widyasari R Wilda Wildaniah Winda Tahuhiddah