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Al Munawir
Department Of Pathology, Faculty Of Medicine, University Of Jember, Jember, 68121 Indonesia
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Journal : Majalah Kedokteran Gigi Indonesia

 1 
Pengaruh Lama Perendaman terhadap Absorpsi Tetrasiklin pada Adsorben Limbah Sisik Ikan Gurami (Osphronemus Gouramy) Sabrina M Pratama; Ghiza J.K. Barqly; Retno Widyastuti; Rizka N Wardani; Dear F Sielma; Al Munawir
Majalah Kedokteran Gigi Indonesia Vol 1, No 2 (2015): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (937.057 KB) | DOI: 10.22146/majkedgiind.9231

Abstract

Influence of Immersion Length on Tetracycline Absorption on Gourami (Osphronemus Gouramy) Scales as Adsorbent. Gourami (Osphronemus Gouramy) scales are one of the natural sources of collagen. This fish scale’s collagen has functional properties, such as bio-degradable (easily decomposed), bio-compatible (compatible with surrounding tissue), and potential as bio-adsorbent. The absorbent properties of collagen are currently used as a transport material in local drug delivery for periodontal disease treatment, which is known as tetracycline chip. However, this chip is made of synthetic collagen so it is not absorbable by the body’s system. The price is also expensive. This study’s aim is to prove the potency of Gourami scales as a source of collagen in medical treatment, especially as a transport material of tetracycline for periodontal disease treatment. The gourami scale was obtained from seafood restaurant in Jember, Jawa Timur. About 500 mg of gourami scales was immersed into 20 ml tetracycline solution in beaker glass. About 200 μl solution from the beaker glass was taken with micropipette after 1-hour, 2-hour, 4-hour, 12-hour and 24-hour after immersed. After that, the solution was collected into an eppendorf for each time. The absorbance was measured with spectrophotometer at 450 nm wave length. This procedure was repeated five times. The lowest absorbance occured at 1-hour time (160,6 μg/μl). The result from light and inverted microscope examination shows a bond between collagen from gourami scales with tetracycline. Gourami scale has the ability to absorb the highest rate of tetracycline at 1-hour immersed time by forming a bond between collagen and tetracycline.
Co-Authors . Zulfan Abd, Misswar Abd, Miswar Achmad, Fariz Ade Ananta Pratiwi Adelia Handoko Adinningtyas Intansari Adji, Novan K. Agung Sudrajat Agung_Sudrajat Agung Aini Hidayati Ali Santoso Alimas Jonsa Alloysius Vendhi Prasmoro, Alloysius Vendhi Anang Dwi Atmoko Ancah Caesarina Novi Marchianti Anhar Fazri Asti Nuris ASTUTI, IDA SRI SURANI WIJI Aulia Rahman Aulia, Tesya Ayik Nikmatul Laili Azka Darajat Bachtiar, Dandi Bagus Indra Kusuma Darmawan, Reza Dear F Sielma Desi Maulida Desy Tariustanti Desy Tariustanti Dewi Rokhmah dian febrianti Dika Pangestu, Yusufa Dori Yuvenda Edy Kurniawan Elfian Zulkarnain Elfian Zulkarnain, Elfian Erfan Efendi Erma Sulistyaningsih Farida Wahyu Ningtyias, Farida Wahyu Farida Wahyuningtiyas Farizal, Teuku Futri Syam Ghiza J.K. Barqly Hadi Prayitno Hartati, Rita Hasdi, Syaiful Hazmi Dwinanda Nurqistan Hendri, Afrizal Herdi Susanto Herri Darsan Hilda Khairinnisa I Gusti Ngurah Agung Darma Putra Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Ikmala, Riskita Isa Marufi ISLAMI, SHOFI IQDA Jalil, Muhammad Jauhar Firdaus Jayadi, Farid Jumanto Jumanto Kamarullah Kamarullah Kiky Martha Ariesaka kustin uds Laili, Ayik Nikmatul laili, Ayik Nikmatul Laksmi Indreswari Luluk Faridatul Mukaromah M. Yasep Setiawan Mahmuddin Marbun Maidi Saputra Masykur, Masykur Meylis Safriani Mirza Adia Nova Muazar, Muazar Mudzakkir Taufiqurrahman Muflikhatun, Khanif Muhammad Abrar Muhammad Aqib Husni Fadhli Muhammad Arif Nasution Muhammad Herizal Ihza Muhendra, Rifki Mulkan, Andi Murhaban Murhaban Murhaban Murtadho Ridwan Muzakir Muzakkir Muzakkir N. Nazaruddin Nabiel, Rifaldy Nadia Putri Yurianto Nafolion Nur Rahmat, Nafolion Nur Nanda Prima Natasya Febrilia Yulianti Novan K. Adji Pandan, Pandan wangi Pipiet Wulandari Pribadyo, Pribadyo Putri Erlinda Kusumaningarum Putri Kemala Sari Putri, Gusfita Trisna Ayu Raudhatun Nafisah Retno Widyastuti Riskita Ikmala Rita Fazlina Rizka N Wardani Rizki, Julia Roat Yeti Mustafida Romadhon, Nadia Jean Rosita Dewi Rudy Gunawan Sabrina M Pratama Safrirullah Safrirullah Saiful Bukhori Saiful Bukhori, Saiful Bukhori Salman Al Farisi samsunan Sarwendah Siswi Winasis Sayyidah Auliany Aminy Sekar Arum Srigati septa surya wahyudi, septa surya SHOFI IQDA ISLAMI Sihaan, Josua Cornel Roni Silvi Ahmada Chasya Solihin Solihin Solihin, Solihin Solihin Sri Wahyu Handayani Sugiyanta Sugiyanta Sukhairi, Teuku Ariessa Supangat Supangat Supangat Supangat Supangat Syahrul Fathi Syari, Zammiq Utami, Nastiti Bekti Vita Alfiatul Hasanah Wahyu Dian Puspita Widyantoro, Murwan Wiqodatul Ummah Y, Fadhil Yasrizal Yulianti, Natasya F. Yusnan, Muhammad Zahrah Febianti Zakir Husin Zarah Puspita Zarah Puspitaningtyas Zuhrizal Fadhly Zulfadhli Zulfadhli Zulfan Adi Putra