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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Ilmiah Farmasi Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Pharmascience Majalah Farmaseutik PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia JFIOnline CERATA Jurnal Ilmu Farmasi Jurnal Ilmiah Cendekia Eksakta Jurnal Inovasi Teknik Kimia Indonesia Natural Research Pharmaceutical Journal (INRPJ) Infokes : Jurnal Ilmiah Rekam Medis dan Informasi Kesehatan Media Farmasi Indonesia
Mimiek Murrukmihadi
Department Of Pharmaceutical, Faculty Of Pharmacy, Universitas Gadjah Mada Sekip Utara Yogyakarta 55281
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary Other

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Journal : Jurnal Ilmiah Farmasi

 1 
FORMULASI TABLET EKSTRAK KANGKUNG AIR (Ipomoea aquatica F.) DENGAN VARIASI KADAR AMILUM MANIHOT SEBAGAI BAHAN PENGHANCUR Sutrisna Khaidir; Mimiek Murrukmihadi; Aris Perdana Kusuma
Jurnal Ilmiah Farmasi Vol. 11 No. 1 (2015): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol11.iss1.art1

Abstract

Ipomoea aquatica F. are plant that has a hypoglycemic effect. Ipomoea aquatica F. was  formulated into tablet dosage forms to produce benefits in terms of practicality and accuracy of therapeutic doses.Disintegrant has effect to release the active substance rate of the tablet so that drug effects can be felt by patients with diabetic immediatly. The purpose of this study was to determine disintegration time of Ipomoea aquatica F. extract tablets with various levels of amilum manihot and determine the best concentration of amilum manihot based on the evaluation of physical properties of tablets.Ipomoea aquatica F. extracts was obtained from the maceration using 96% ethanol, than concentrated by rotary evaporator. The extracts were tested qualitatively by TLC with petroleum eter: aceton: dietil amin mobile phase (10:4:1), the phase silica gel F254 with Rf value about 0,625.  Tablets were formulated with amilum manihot concentration variation of 10%, 15% and 20% by wet granulation method. Physical properties of granules were tested such as powder flow, angle of repose, porosity and compressibility index.Tablets were tested to know physical properties such as weight uniformity, sizeuniformity, hardness, friability and disintegration time.The results showed that variaton levels of amilum manihot decrease disintegration time. Variation of amilum manihot was affected in disintegration time, and the optimumt formula with was achieved by 15% amilum manihot. 
PENGARUH PEMBERIAN VARIASI CAMPURAN SORBITOL DAN GLUKOSA CAIR SEBAGAI PEMANIS PADA SEDIAAN GUMMY CANDY PARASETAMOL Lutfi Chabib; Mimiek Murrukmihadi; Aprianto Aprianto
Jurnal Ilmiah Farmasi Vol. 10 No. 2 (2013): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol10.iss2.art5

Abstract

Gummy candy parasetamol adalah sediaan permen kenyal mengandung parasetamol yang ditujukan untuk hancur dan larut di dalam mulut. Tujuan penelitian untuk mengetahui pengaruh variasi campuran pemanis sorbitol dan glukosa cair terhadap sifat fisik sediaan gummy candy parasetamol. Pembuatan sediaan menggunakan metode cetak tuang dengan perbandingan konsentrasi sorbitol dan glukosa cair: 50:50, 40:60, 30:70, 20:80, dan 10:90%. Data yang diperoleh dianalisis dengan deskriptif non analitik. Hasil uji sifat fisik dan uji stabilitas fisik sediaan dengan parameter bentuk, rasa, aroma, tekstur, pengamatan kekakuan, pengamatan kristal, dan pH sediaan. Formula 1 (50:50%) memiliki rasa yang sedikit manis dan stabil dalam penyimpanan selama sebulan di climatic chamber suhu 25oC dibandingkan formula yang lain. Hasil persentase uji hedonik (bentuk, rasa dan aroma) pada 28 responden dari formula 1 sampai formula 5 berturut-turut: 25; 60,7; 3,5; 0, dan 10,7%. Semakin tinggi kadar sorbitol maka sediaan yang dihasilkan semakin manis dan meningkatkan kekerasan. Sedangkan semakin tinggi kadar glukosa cair maka sediaan semakin kenyal dan mencegah kerusakan tekstur gummy candy parasetamol
Co-Authors Ami Afiyati Ami Afiyati, Ami Ana Indrayati Anif Nur Artanti, Anif Nur Aprianto Aprianto Aris Perdana Kusuma Desti Wibowo Dewi Andini K.M. Dewi Andini Kunti Mulangsri, Dewi Andini Kunti Diana Cholida Dias Anita Fajarini Dias Anita Fajarini, Dias Anita Dinar Hesti Permatasari Dinar Hesti Permatasari, Dinar Hesti Elya Zulfa Eni Muaniqoh Fea Prihapsara Fea Prihapsara, Fea Hanum Pramuji Afianti Herman Widjaja Iswandi - Kurniati Pamungkas Kurniati Pamungkas, Kurniati Lutfi Chabib, Lutfi Marchaban . Marchaban Marchaban Marchaban Marchaban Marchaban Marchaban, Marchaban Marchaban, . Marchaban, . Marlyn Dian Laksitorini Mualifah Rifiani Ela Rosita Mutmainah Mutmainah3 Naniek Widyaningrum Nur Laili Nurhayati Nurul Nurul Hidayati PRAISELA RIZDHANIA Prihapsara, Fea Rahmawati, Nur Laili Rani Dewi Pratiwi Rizka Ariani Rizki Ananda Rizki Fajar Roni Ferdian Siti Aisiyah Sri Mulyani Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Sudibyo Martono Sudibyo Martono Sudibyo Martono Sudibyo Martono Sugiyono - Sutrisna Khaidir Suwarmi Suwarmi Syarifatun Karunia Ekawati Tegar Bagus Prasetyo Teuku Nanda Saifullah Teuku Nanda Saifullah Tiar Rizki Hayu Tri Utami Handayani Veronica Intani Suherndra Wahyuni Watora Wibowo, Danang Novianto Yogaswara Tawang Gumbara Zein, Halimatus Sa' diyyah