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All Journal Jurnal Ilmiah Farmasi Indonesian Journal of Pharmaceutical Science and Technology Pharmascience Journal of Islamic Pharmacy Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Farmasains : Jurnal Ilmiah Ilmu Kefarmasian SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Kreativitas PKM Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal) Jurnal Kesehatan Islam : Islamic Health Journal PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Real in Nursing Journal Pharmacoscript Borneo Journal Of Pharmascientech Jurnal Mandala Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Sains Medisina Majalah Cendekia Mengabdi Journal of Pharmaceutical and Sciences. Jurnal Farmasi SYIFA Borneo Journal of Pharmacy KOPEMAS
Rahmi Muthia
Fakultas Farmasi, Universitas Borneo Lestari, Banjarbaru, Kalimantan Selatan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Comparison of Extraction Solvents Towards Anti-Propionibacterium acnes activity of Alphitonia incana (Roxb). Teijsm. & Binn. ex Kurz Leaves Hafiz Ramadhan; Rahmi Muthia; Sari Wahyunita; Dyera Forestryana; Sherly Mar'atu Soleha; Lihimi Lihimi
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 5, No. 1 (2023)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v0i0.45897

Abstract

Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz locally known as Balik Angin in Borneo Island is one of the endemic plants that have the potential to be an alternative antibacterial agent. Balik Angin leaves contain secondary metabolites that have to play a role to inhibit the growth of Gram-positive bacteria. This study aimed to compare the different extraction solvents which are methanol and ethanol on the maceration of Balik Angin leaves in producing antibacterial activity against Propionibacterium acnes. The leaves were macerated using methanol and ethanol respectively. Antibacterial assay was carried out by the Well diffusion method. The results showed minimum inhibitory concentration (MIC) of ethanol extract which is 3.2% has a diameter of clear zone of 9.475±0.311 mm. Meanwhile, the methanolic extract with a similar MIC has a lower diameter of clear zone of 2.55±0.85 mm. The results correlate with the number of secondary metabolites groups that were identified based on phytochemical screening in ethanol extract containing alkaloid, phenolic, flavonoid, tannin, saponin, and phytosteroid, however, methanol extract not containing alkaloid. The conclusion of this study is ethanol solvent more effective to extract secondary metabolites from Balik Angin leaves compare to methanol solvent, so that can produce more powerful anti-Propionibacterium acnes activity.
Co-Authors Abdurrahman Sidiq Aditya, Aditya Noviadi Rakhmatullah Afra, Fairuz Yaumil Ahmad ahmad - Maulana Akbar, Depy Oktapian Alfina, Sophia Amalia - - Amalia, Elfa Annisa Aminuyati Ananda, Lutfhia Rizky Aristha Novyra Putri Arnida Arnida Arnida Arnida Arsyad, Zyrzasya Sofia Nara Astuti, Karunita Ika Azhari, Fajar Bin Jamaludin, Wahyudin Citra Kharisma Dewi Dally Rahman Dewi, Citra Kharisma Dyera Forestryana Dyera Forestryana Eka Fitri Susiani Elfa Annisa Amalia Emil Huriani Fatimah Nursandi Fatimah Nursandi Fatmawati Fatmawati Fauzana, Erwin Finna Setiawan Fitri Mailani Fitri, Tiya Rama Fitriyanti, Fitriyanti Gina Rizki Zanirah Gunawan Gunawan Gunawan Gunawan Guntur Kurniawan Gusti - Rizaldi Hafiz Ramadhan Hafiz Ramadhan Helmina Wati Hidayatullah, M. Hidayatullah Hidayatullah, Muhammad Indah Widya Lestari Istiqamah, Qanita Kartini Kartini Kartini Khatijah Lim Abdullah Kurniawan, Guntur Liana Fitriani Hasymi Lihimi Lihimi Lulu Damayanti Lutfhia Rizky Ananda Maulidya Rasyida Putri Mochammad Maulidie Alfiannor Saputera Muhammad Hidayatullah Muhammad Hidayatullah Muhammad Hidyatullah Nabila Saputri Nafila, Nafila Normilawati, Santi Nurbidayah Nurul Asfia Oktarina, Elvi Puspawati, Puspawati Putri Indah Sayakti Putri, Aristha Novyra Putri, Putri Indah Sayakti Rahimah Rahmayanti Fitriah Rahmi Hidayati Rahmi Hidayati Rakhmatullah, Aditya Noviadi Ramadhan, Hafiz Revi Kunmariana Rina Helmina Rizka Ayu Wahyuni Sandi, Dita Ayulia Dwi Saputri, Revita Sari Wahyunita Saufi, Muhammad Selva - Amadia Septiyani Candrakirana Sherly Mar'atu Soleha Sophia Alfina Sulastri Azistina Verawati Syawaliyah, Syawaliyah Syifa Untung Santoso Untung Santoso Vebruati Vebruati Vebruati Vebruati Vina Salviana Darvina Soedarwo Vina Salviana Darvina Soedarwo Vina Salviana Darvina Soedarwo Wahyudin Bin Jamaludin Wahyudin Bin Jamaludin Yaumi Musfirah Yuliana Yuliana Yuni Fahriana Yusmalina Yusmalina Yustin Ari Prihandini Yustin Ari Prihandini