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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin
Sawitri Sawitri
Departemen / Staf Medik Fungsional Kesehatan Kulit Dan Kelamin Fakultas Kedokteran Universitas Airlangga/Rumah Sakit Umum Daerah Dr. Soetomo Surabaya
Immunology & microbiology Public Health

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Journal : Berkala Ilmu Kesehatan Kulit dan Kelamin

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Chickenpox Mimicking Monkeypox in Adult with Diabetes Mellitus and Acute Kidney Injury: Diagnosis and Management Maya Wardiana; Rahmadewi Rahmadewi; Dwi Murtiastutik; Sawitri Sawitri; Damayanti Damayanti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.213-223

Abstract

Background: Chickenpox caused by the varicella-zoster virus (VZV) in diabetes mellitus patients might exhibit similar clinical features with monkeypox, caused by monkeypox virus (MPXV). In May 2019, Singapore notified World Health Organization (WHO) of one laboratory-confirmed case of monkeypox. Considering Singapore is located near Indonesia, awareness about the possibility of an outbreak in Indonesia should be raised. Purpose: To report a case of chickenpox mimicking monkeypox in an adult with diabetes mellitus and acute kidney injury. Case: A 51-year-old male with poorly controlled diabetes mellitus was suspected to have a chickenpox differential diagnosis with monkeypox. His chief complaint was multiple blisters on his body and vomiting. There was a history of feeding a monkey. From dermatological status on facial, trunk, and extremities there were multiple pleomorphic vesicles. Laboratory results showed elevated renal function. Polymerase chain reaction (PCR) examination using VZV as primer revealed a positive result in the range of 810 bp. He was treated with intravenous acyclovir for 3 days and oral acyclovir for 7 days then discharged with improvement in skin lesions and normal renal function. Discussion: Chickenpox in adult and diabetes mellitus patients can give severe clinical manifestation mimicking monkeypox. PCR has a significant role especially when diagnosis could not be established from the physical examination. Acyclovir can be given as the therapy. Conclusion: Adult and poorly controlled diabetes mellitus are important risk factors associated with the severity and complication of chickenpox. A careful diagnostic approach and management are needed.
The Efficacy of Lactobacillus plantarum as Adjunctive Therapy of Bacterial Vaginosis: A Double-blind, Randomized, Placebo-controlled Trial Ridha Ramadina Widiatma; Muhammad Yulianto Listiawan; Dwi Murtiastutik; Cita Rosita Sigit Prakoeswa; Sawitri Sawitri; Ingrid Suryanti Suryono; Linda Astari; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 32 No. 3 (2020): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V32.3.2020.214-220

Abstract

Background: Bacterial vaginosis (BV) is a clinical syndrome caused by the changing of Lactobacillus spp., a producer of hydrogen peroxide, in the normal vagina with a high concentration of anaerobic bacteria, Gardnerella vaginalis and Mycoplasma hominis. This study reports a resistance of BV therapy regimens, high recurrence rates, and side effects of an antibiotic. Therefore, adjunctive therapy for BV management is needed. Research has reported the therapeutic effects of probiotic in BV; however, the results are inconsistent. Purpose: To evaluate the efficacy of standard therapy using metronidazole and Lactobacillus plantarum for BV measured by the cure rate and vaginal flora balance. Methods: A randomized, double-blind, placebo-controlled trial, 30 subjects were randomized to take metronidazole 500 mg twice a day for seven days with weekly evaluation. The Lactobacillus plantarum or placebo group was evaluated every 4 weeks. The cure rate and vaginal flora balance were evaluated using the Amsel criteria and Nugent score before and after the intervention. Result: A total of 30 subjects returned for 28-day follow-up, of which 60% subjects of the antibiotic/probiotic group were cured compared to 40% in the antibiotic/placebo group (p>0.05). Conclusion: There was no difference in the increase of cure rate and vaginal flora balance between the treatment group and significant control group.
The Comparison of Candida spp. Colonization on Psoriasis Vulgaris Patient and Control Amanda Gracia Manuputty; Dwi Murtiastutik; Sawitri Sawitri; Muhammad Yulianto Listiawan; Rahmadewi Rahmadewi; Afif Nurul Hidayati; Pepy Dwi Endraswari; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.40-47

Abstract

Background: Psoriasis is an inflammatory, chronic, and recurring skin disease that affects patient’s quality of life. Environment, drugs, and infections in the form of antigen and toxin such as Candida spp. are assumed responsible for triggering and exacerbating psoriasis. Purpose: To compare the prevalence of skin colonization of Candida spp. on psoriasis vulgaris patient and control. Methods: This study was observational analytic research involving 33 psoriasis vulgaris patients and 33 healthy individuals. They were matched up based on sex, age, and lesion location. Swab of skin lesions on the Koebner area of both groups was cultured on CHROMagar media. Candida spp. was later identified and the colonization was calculated. Result: Candida spp. was found on 51.5% of lesions in psoriasis vulgaris patients and 21.2% in the control group with a significant difference of p < 0.05. The average colony number of Candida spp. in psoriasis vulgaris group was lower than the control group with no significant difference of p > 0.05. The predominant Candida spp. in the psoriasis vulgaris and control groups was Candida krusei, which were 35.5% and 85.6%, respectively. No significant difference between sex, age, period of complaints, age onset, degree of severity (Psoriasis Area and Severity Index), and therapy history, with positive culture of Candida spp. Conclusion: There was no difference in the number of Candida spp. colonization in the psoriasis vulgaris group and the control group. However, the culture positivity of Candida spp. in the psoriasis vulgaris patients was higher than in the control group.
A Retrospective Study: Risk Factor Analysis of Secondary Bacterial Infection in Pediatric Atopic Dermatitis Patients Desiana Widityaning Sari; Sawitri Sawitri; Muhammad Yulianto Listiawan; Dwi Murtiastutik; Linda Astari; Alpha Fardah Athiyyah; Afif Nurul Hidayati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.83-87

Abstract

Background: Atopic Dermatitis (AD) is a complex multifactorial disease that includes defects in skin architecture, immune dysregulation, and changes of skin flora, and it predominantly occurs in infancy and childhood. The defects in skin barrier structures are mentioned as one of the factors that facilitates bacterial colonization. Bacterial infection in AD can worsen the inflammation. It requires treatment with antibiotics, which takes longer therapy time, higher costs, and ultimately affects the patient’s quality of life and his/her family members. Purpose: To find out the epidemiology, diagnosis, management of AD, and analyze the risk factors of secondary bacterial infection in new AD patients at the Pediatric Dermatology Division, Dermatovenereology Outpatient Clinic, Dr. Soetomo General Academic Hospital. Methods: This was a retrospective study with a total sampling method. The research data were medical records of new AD patients at the Pediatric Dermatology Division, Dermatovenereology Outpatient Clinic, Dr. Soetomo General Academic Hospital Surabaya from January 2012 to December 2018. Result: There were 404 new patients with AD at the Pediatric Dermatology Division from January 2012 to December 2018, and 210 of them were accompanied by secondary bacterial infection. There was a correlation between a history of dry skin (p=0.000) with the incidence of secondary bacterial infection in AD patients. Conclusion: In this study, AD patients with a history of dry skin had a risk of complication such as bacterial secondary infection.
Co-Authors Afif Nurul Hidayati Agatha Anindhita Ardhaninggar Alpha Fardah Athiyyah Amalia Rositawati Amanda Gracia Manuputty Ardhiah Iswanda Putri Asmahani Thohiroh Bagus Meurah Suropati Chesia Christiani Liuwan Cita Rosita Sigit Prakoeswa Cita Rosita SP Damayanti Damayanti Damayanti Damayanti Damayanti Damayanti Desiana Widityaning Sari Diah Mira Indramaya Dwi Murtiastutik Dyah Ayu Pitasari Dyatiara Devy Rahadiyanti Eko Budi Koendhori, Eko Budi Emma Hidayati Sasmito Endang Wahyu Fitriani Esti Hendradi Evy Ervianti Farhat Surya Ningrat Frea Astrilia Tamarina Hari Sukanto, Hari Icha Aisyah Ingrid Suryanti Suryono Irmadita Citrashanty Iskandar Zulkarnain Kurniati Kurniati Linda Astari, Linda M. Yulianto Listiawan Maya Wardiana Nurina Dhani Rahmayanti Pepy Dwi Endraswari, Pepy Dwi Rahmadewi Rahmadewi Regitta Indira Agusni Renata Prameswari Retha Retha Ridha Ramadina Widiatma Riezky Januar Pramitha Riyana Noor Oktaviyanti Shinta Dewi Rahmadhani Shinta Dewi Rahmadhani Wahyunita Desi Ratnaningtyas Willy Sandika Yuri Widia, Yuri