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Journal : Jurnal Ilmu-Ilmu Peternakan (Indonesian Journal of Animal Science)

Nutritional and Antioxidant Evaluation of Herbal Pulp Oryza sativa and Kaempferia galangal L. for Potential Use of a Feed Additive in Poultry Prihatiningsih; Sjofjan, Osfar; Natsir, Muhammad Halim
Jurnal Ilmu-Ilmu Peternakan Vol. 35 No. 2 (2025): August 2025
Publisher : Faculty of Animal Science, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jiip.2025.035.02.10

Abstract

Herbal pulp from the production of beras kencur (a traditional Indonesian herbal drink made from Oryza sativa and Kaempferia galangal L.) is an underutilized byproduct that contains valuable nutrients. This study aimed to determine the nutritional content of Oryza sativa and Kaempferia galanga L. herbal pulp through proximate analysis and the evaluation of antioxidant compounds. The experiment employed four treatments: T1 (35% Kaempferia galanga L., 40% Oryza sativa, 5% pandan leaves, 20% palm sugar and water), T2 (50% Kaempferia galanga L., 35% Oryza sativa, 15% brown sugar and water), T3 (35% Kaempferia galanga L., 45% Oryza sativa, 20% brown sugar and water), and T4 (40% Kaempferia galanga L., 40% Oryza sativa, 20% brown sugar and water). The best treatment was T3, with 88.40% dry matter, 11.60% crude protein, 10.92% crude fat, 7.71% crude fibre, 67.42% nitrogen-free extract (NFE), 1.74% ash, 3991.29 kcal gross energy, pH 3.66, and 23.810 ppm antioxidant activity. Treatment T3 has the potential to be used as a feed additive for poultry, with a maximum inclusion rate of 1%. In summary, this study provides novel insight, as it is the first to comprehensively assess the proximate composition and antioxidant potential of Oryza sativa and Kaempferia galanga L. herbal pulp for its application as poultry feed additives.
Laying Hens Growth Performance in the Peak Production Phase Offered Bio-Herbal as a Feed Additive Nuningtyas, Yuli Frita; Natsir, Muhammad Halim; Widyastuti, Eny Sri; Sjofjan, Osfar; Susilo, Agus; Widiati, Aris Sri; Lestari, Suci Puji
Jurnal Ilmu-Ilmu Peternakan Vol. 33 No. 1 (2023): April 2023
Publisher : Faculty of Animal Science, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jiip.2023.033.01.04

Abstract

The aim of this research was to evaluate the effect of the addition of bio-herbal as a feed additive on feed consumption, hen day production, feed egg ratio and mortality of laying hens. The materials in this experiment used 200 laying hens of the Hyline strain age 28 to 36 weeks (reared for 60 days). The method used in this study was an in vivo experimental method using a Completely Randomized Design (CRD) with treatments consisting of P0 = drinking water without bio-herbals (control treatment), T1 = control treatment + bio-herbal yellow, P2 = control treatment + bio-herbal green, and T3 = control treatment + bio-herbal combination yellow and green (alternately every one week). Data were analyzed using Analysis of Variance (ANOVA) and if there was a significant effect, then tested with Duncan's Multiple Range Test. The observed variables were feed consumption, Hen Day Production (HDP), feed egg ratio and mortality. The results showed that the addition of bio-herbals had no significant effect (P > 0.05) on the feed consumption, hen day production, feed egg ratio and mortality. It can be concluded bio-herbal green gives the best results in improving egg quality. Due to the bioactive compounds of bio-herbal green, they consist of probiotic and phytobiotic.
In Silico Study of Bioactive Compounds from Yellow Bioherbal as Potential LpxC Protein Inhibitors for Controlling Pathogenic Bacteria in Broiler Chicken Intestinal Yusuf, Zaen; Natsir, Muhammad Halim; Sjofjan, Osfar
Jurnal Ilmu-Ilmu Peternakan Vol. 34 No. 1 (2024): April 2024
Publisher : Faculty of Animal Science, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jiip.2024.034.01.10

Abstract

Bioherbal, a feed additive made from rhizome extract, exhibited promising capabilities in eradicating pathogenic bacteria residing within the digestive tracts of broiler chickens. The LpxC protein, a biosynthetic regulator of lipid A (a critical component of gram-negative bacterial cell walls), was the focus of this research. Our primary objective was to assess the bioactive potential of bioherbal as a prospective inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine (LpxC) by employing in silico methods. Computational analyses were employed to scrutinize the interactions between the LpxC protein and various ligands on Bioherbal. Molecular docking served as the initial screening process, evaluating 48 bioactive compounds based on energy affinity, conformation values, and interactions with protein residues. The three compounds exhibiting the lowest binding affinities were subjected to molecular dynamics simulations. Molecular docking analysis revealed that most of the screened compounds exhibited low binding affinity for LpxC. Elephantorrhizol, zedoraldehyde, glechomanolide, demethoxycurcumin, curcumin, hexahydrocurcumin, gweicurculactone, germacrone, and 1,2-dihydrocurcumin exhibited lower binding affinities (<-7 kcal/mol). Elephantorrhizol, curcumin, and hexahydrocurcumin were selected for further analysis via molecular dynamics due to their similarity to native ligands. Molecular dynamics simulations revealed stable interactions of LpxC. In summary, these findings suggested that Bioherbal possesses the potential to function as an LpxC inhibitor, thereby offering a promising avenue for preventing the proliferation of gram-negative bacteria within the digestive tracts of broiler chickens. This computational study paves the way for further experimental investigations in this domain.