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All Journal JURNAL ILMIAH KESEHATAN KEPERAWATAN Jurnal Kesehatan Reproduksi JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Jurnal Kesehatan Reproduksi Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Kesehatan Holistic Manuju : Malahayati Nursing Journal Jurnal Keperawatan Respati Yogyakarta Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Journal of Community Empowerment for Health Berita Kedokteran Masyarakat Jurnal Pengabdian Masyarakat Bhinneka Community Development in Health Journal Jurnal Keperawatan Profesional Service Quality (Jurnal Pengabdian Masyarakat)
Shinta Prawitasari
Department Of Obstetrics And Gynaecology, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada/Dr Sardjito Hospital, Yogyakarta, Indonesia
Agriculture, Biological Sciences & Forestry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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Journal : Manuju : Malahayati Nursing Journal

 1 
Intervensi Nonfarmakologis sebagai Solusi Kelelahan pada Pasien Kanker Payudara: Sebuah Tinjauan Sistematik Panjaitan, Ribka Sabarina; Sibualamu, Khalida Ziah; Harahap, Sarah Geltri; Prawitasari, Shinta; Setyaningsih, Tri; Ludovikus, Ludovikus
Malahayati Nursing Journal Vol 7, No 10 (2025): Volume 7 Nomor 10 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i10.22320

Abstract

ABSTRACT Fatigue is one of the most common and debilitating symptoms experienced by breast cancer patients, particularly during chemotherapy. Pharmacological management often remains insufficient, highlighting the need for safe and effective non-pharmacological interventions. To systematically identify and analyze various non-pharmacological interventions used to manage fatigue in breast cancer patients undergoing chemotherapy. This study employed a systematic review method following the PRISMA and Joanna Briggs Institute guidelines. Literature was searched from databases including PubMed, ScienceDirect, and Sagejournal using PICOT-based keywords. Included articles were Randomized Controlled Trials (RCTs) studies, published in English between 2015 and 2025.Results: Out of 585 articles identified, 6 met the inclusion criteria. The reviewed studies demonstrated the effectiveness of several non-pharmacological interventions in reducing cancer-related fatigue, including ATAS acupuncture, structured physical exercise programs (aerobic and strength training), yoga, and traditional Chinese herbal medicine (XBYRT). These interventions also showed additional benefits on sleep quality, anxiety, depression, and overall quality of life. Non-pharmacological interventions show significant potential in alleviating fatigue among breast cancer patients undergoing chemotherapy. A holistic approach that integrates physical, psychological, and spiritual strategies is recommended to improve patient well-being. Further large-scale and long-term studies are warranted to strengthen these findings. Keywords: Breast Cancer, Chemotherapy, Fatigue Non-Pharmacological Interventions ABSTRAK Kelelahan merupakan salah satu gejala paling umum dan melemahkan yang dialami pasien kanker payudara, terutama selama menjalani kemoterapi. Penanganan kelelahan dengan pendekatan farmakologis seringkali belum optimal, sehingga diperlukan strategi tambahan berupa intervensi nonfarmakologis yang aman dan efektif. Mengidentifikasi dan menganalisis secara sistematik berbagai intervensi nonfarmakologis yang digunakan untuk mengatasi kelelahan pada pasien kanker payudara yang menjalani kemoterapi. Penelitian ini menggunakan metode systematic review dengan mengacu pada panduan PRISMA dan Joanna Briggs Institute Guideline. Pencarian literatur dilakukan melalui database PubMed, ScienceDirect, dan Sagejournal dengan  kata kunci sesuai format PICOT. Artikel yang dianalisis berjenis Randomized Controlled Trial (RCT), berbahasa Inggris, dan dipublikasikan dalam rentang 2015–2025. Dari 585 artikel yang ditemukan, sebanyak 6 artikel memenuhi kriteria inklusi. Intervensi nonfarmakologis yang terbukti efektif dalam menurunkan kelelahan meliputi akupunktur ATAS, program latihan fisik (aerobik dan kekuatan), yoga, dan ramuan herbal TCM (XBYRT). Efek positif juga terlihat pada aspek tambahan seperti kualitas tidur, kecemasan, depresi, dan kualitas hidup pasien. Intervensi nonfarmakologis terbukti memberikan manfaat signifikan dalam mengurangi kelelahan pada pasien kanker payudara selama kemoterapi. Penggabungan pendekatan fisik, psikologis, dan spiritual melalui intervensi yang terencana dapat menjadi strategi holistik dalam meningkatkan kualitas hidup pasien. Diperlukan penelitian lanjutan dengan jumlah sampel lebih besar dan durasi yang lebih panjang untuk memperkuat temuan ini. Kata Kunci: Intervensi Nonfarmakologis, Kanker Payudara, Kelelahan, Kemoterapi.
Co-Authors Adi Heru Sutomo Adintyo Rahman, Muhammad Nur Adolfina Nilasari Ahsanudin Attamimi Ajeng Arumsari Yayi Pramesti, Ajeng Arumsari Amiruddin Amiruddin Anisa, Tiara Aulia Ardhanu Kusumanto Ariawan Soejoenoes Astuti, Dyah Puji Beti Wulansari Brantas Prayoga Carla Raymondalexas Marchira Carla Raymondalexas Marchira, Carla Raymondalexas Chairunisa, Ratu Chamy Rahmatiqa Dalri Nur Fidina Diah Rumekti Hadiati Diannisa I E Sangun Efriyan Imantika Eka Mega Sari Ernawati Ernawati Eugenia Maria Alodia Hartono Evi Septiani Fidina, Dalri Nur Hafizh, Muhammad Raihan Hanif Reza Hanifah Mirzanie Harahap, Sarah Geltri Hardiknas Steven Saneba Herlina Pradjatmo Heru Pradjatmo ika putri ika putri Indraswari, Lathifa N Irwan Taufiqur Rachman Ismail Joko Sutresno Kartika Wijayanti Kartika Wijayanti Lathifa N Indraswari Leo Prawirodihardjo Leo Prawirodihardjo Leo Prawirodihardjo Lisa Soldat Ludovikus, Ludovikus Madarina Julia Madarina Julia Mailintina, Yurita Maya Safitri Miftakhul Muslichah Milhan Milhan Milhan Milhan, Milhan Mirzanie, Hanifah Mohammad Hakimi Mora Claramita muhammad hafiizh, muhammad Muhammad Hakimi Muhammad Hakimi Muhammad Lutfi Muhammad Lutfi Muhammad Nurhadi Rahman Muslichah, Miftakhul Nadia Mutiara Zahra Nani Emma Nani Emma Naufal, Hanif Zain Nuring Pangastuti Nuring Pangastuti Nuring Pangastuti, Nuring Ova Emilia Panjaitan, Ribka Sabarina Patricia Alika Kurniawan Pradjatmo, Herlina Prima Daniyati Kusuma Prima Daniyati Kusuma Rahmaningsih, Ary Ramba, Hardin La Refti, Weni Guslia Ridwan, Rizal Risanto Siswosudarmo Rizal Ridwan Rohmah, Ulfa Nur Rukmono Siswishanto Sangun, Diannisa I E Santi Yuliani Saputra, Aldi Sari, Eka Mega Satriagraha, Oky Ardian Shofwal Widad Sibualamu, Khalida Ziah Siswanto Agus Wilopo Soejoenoes, Ariawan Suarti, Ni Made Sumarah Sumarah Sumarah Sumarah Sumarni Sumarni Sutresno, Ismail Joko Tri Setyaningsih Udayani, Ni Putu Eka Chandra Vicky Admiral Aprizano Wahyudi Istiono Wenny Wenny Wenny, Wenny Winda Nurmayani M Yari, Yarwin Yayuk Hartriyanti Yosi Tamara