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Kesaktian Manurung
Program Studi S1 Farmasi, Universitas Sari Mutiara Indonesia

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Journal : Jurnal Farmanesia

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN KEMANGI (Ocimumbasilicum L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcusaureus Kesaktian Manurung; Jon Kenedy Marpaung; Mardianis Mardianis
Jurnal Farmanesia Vol 8 No 1 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Basil (Ocimumbasilicum L.) is one of the natural plants that is easily obtained in Asia such as Indonesia which has medicinal properties. Basil leaves contain flavonoid compounds, tannins, saponins, and steroids/triterpenoids. These compounds are known to have antibacterial activity. This study aims to determine the antibacterial activity of the ethanolic extract of basil leaves (Ocimumbasilicum L.) against Staphylococcus aureus bacteria. This research is experimental. The test was carried out through several stages including material collection, preparation of simplicia, making ethanol extract of basil leaves, and testing the inhibitory power of basil leaves against Staphylococcus aureus bacteria. The ethanol extract of basil leaves was made by the maceration method using 96% ethanol and concentrated with a rotary evaporator to obtain a thick extract from basil leaves. Antibacterial activity was tested by the agar diffusion method using disc paper. The results of the antibacterial activity test showed that the ethanolic extract of basil leaves inhibited the growth of Staphylococcus aureus bacteria at concentrations of extracts of 5%, 10%, 15%, 20%, and 25% with inhibition zone diameters of 8. 31 mm, 9. 43 mm, respectively. 9. 73 mm, 9. 91 mm, and 11. 33 mm. The ethanol extract of basil leaves has antibacterial activity against Staphylococcus aureus bacteria.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN INSULIN (Smallanthussonchifolius) TERHADAP BAKTERI Bacillus cereus Kesaktian Manurung; Ahmad Ghazali; Ahmad Hafizullah; Ulfayani Mayasari
Jurnal Farmanesia Vol 4 No 1 (2017): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Insulin leaves are known as one of the ingredients of traditional medicine. Insulin leaves contain potential substances such as tannins, alkaloids, flavonoids, saponins, and terpenoids which have antibacterial abilities. This study aims to determine the effectiveness of insulin leaf ethanol extract as an antibacterial. This research is an experimental study that includes the collection and processing of insulin leaf samples, examination of the characteristics of Simplisia, phytochemical screening, testing of the antibacterial diffusion method using a disk paper brace, and using the One Way ANOVA analysis method. The test results showed that the ethanol extract could inhibit bacterial growth at a concentration of 50 - 60% with an average resistor potential of 14.8 - 17.83 mm while Ampicillin as a comparison control averaged 33.62 mm. So that the ethanol extract of insulin leaves was effective in inhibiting the growth of Bacillus cereus bacteria with a minimum resistance concentration of 60 mg/ml. Keywords: Antibacterial, Bacillus cereus, insulin leaf extract