Nina Irmayanti Harahap
Institut Kesehatan Deli Husada

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Journal : Jurnal Penelitian Farmasi dan Herbal

EFEK PENYEMBUHAN LUKA BAKAR GEL KOMBINASI EKSTRAK ETANOL DAUN AFRIKA (Vernonia Amygdalina) DAN EKSTRAKETANOLDAUNBANGUN–BANGUN(ColeusamboinicusLour) Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 3 No 1 (2020): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i1.318

Abstract

african leaves ( Vernonia Amygdalina )and wake-up leaves (Coleus amboinicus Lour)are plants traditional plants that are used as medicine. Leaves african which is contain flavonoid, saponin, tanin and leaves wake up which is contain flavonoid, tanin, saponin and steroid. This study to find aims out as effect healing of burns.Method : Sample in this study was african leaves and wake-up leaves which were taken purposively without comparing sampel from other regions, then extrated by maceration using ethanol 96 %. Result : Testing of rhe healing effects of burns can be divided in five treatment, positive group using biolacenton , negatif group using basis gel and the last group using the extract ethanol gel EEDA and EEDB concentrations of 4%+2,5%,8%+5%,16%+10%. Given burns to the back of rabbits length with of 2cm, and the gel is applied twice a day for 11 day and diameter measured of the wound. Conclusion : The combination of EEDA and EEDA the ethanol extract the concentration of 16% + 10% was the effective control for healing burns. When compared bioplacenton gel as a healing wound in rabbit.
FORMULASI DAN UJI STABILITAS LOTION SARI BUAH TOMAT (licopersicon esculentum mill) KOMBINASI KUNYIT (Curcuma domestica Vall) SEBAGAI PELEMBAB KULIT Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 3 No 2 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v3i2.652

Abstract

Antioxidants is contained in various types of fruit and vegetables included of juice tomatoes (Lycopersicum esculentum Mill)that have nutritional value and benefits for the body like lycopene, and vitamin C as antioxidants. Lycopene is function as a strong antioxidant to control free radical. Tumeric (Curcuma domestica Vall) is known have enough curcumin and strong antioxydants content too, and so it has some pharmacological effects. Tomatoes and Tumeric extract (EKSBT) can be made as pharmaceutical preparations in hand and body lotion (H&B lotion),because antioxidants are important components that are used for body protection from ultra violet light and can be applied in the form of a lotion. The purpose of this study was to saw the stability of the H&B lotion combination of that Variations.Combination tomatoes and turmeric extract formulated with concentrations lotion are of 5%, 10%, and 15%. The lotion of EKSBT these combination were evaluated some test there are organoleptic, homogeneity, pH test, spreadability, irritation and preference test.EKSBT combination can be formulated into lotion preparations. The various of all concentrations lotion EKSBT showed that stable during instorage, give a homogeneous yellow color with pH of 5-6 and a spread of 5-6 cm, does not irritate the skin and is preferably the volunteer.Physical stability EKSBT lotion test all concentration are stable, the preferred test of odor, easy to be smeared and moisturizing shows that the most preferred EKSBT lotion is the highest concentration 15%.
UJI FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN PACAR (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus DAN Pseudomonas aeruginosa Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 4 No 1 (2021): Jurnal Penelitian Farmasi & Herbal
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v4i1.767

Abstract

Background: Indonesia is a country rich in natural resources that can be used as traditional medicine. Pacar leaf extract (Lawsonia inermis L.) can be formulated into ointment preparations, can inhibit the growth of staphylococcus aureus (SA) and pseudomonas aeruginosa (PA) bacteria and determine the best inhibitory concentration. Methods: This research method was experimental, the extract was obtained by maceration method with 80% ethanol solvent, then ointment was made using adeps lanae base, vaseline album and Pacar leaf extract ointment hadcombination concentrations 8%, 12% and 16%. The results of the study: The results showed that Pacar Leaf Extract (SEEDP)could be formulated as an ointment preparation and met the requirements for quality testing of ointment preparations, including characterization tests and phytochemical screening tests. The results of the antibacterial activity test showed that the formulation of the ointment preparations of Pacar Extract with concentrations of 8%, 12% and 16% could inhibit the growth of bacteria and good inhibition of 16% with an average diameter of bacteria (SA). 11.93 mm and bacteria (PA) 17.2 mm.It was concluded that the higher the concentration of the extract, the greater the inhibition given. The preparation of pacar leaf extract ointment with concentrations of 8%, 12% and 16% was the best ointment in inhibiting the growth of bacteria (SA) and (PA)
Uji Aktivitas Antibakteri Ekstrak Etanol Daun Rambutan (Nephelium lappaceum L) Pada Pertumbuhan Bakteri Staphylococcus aureus dan Escherichia coli Nina Irmayanti Harahap
Jurnal Penelitian Farmasi & Herbal Vol 5 No 1 (2022): JURNAL PENELITIAN FARMASI & HERBAL
Publisher : Fakultas Farmasi Institut Kesehatan DELI HUSADA Deli Tua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36656/jpfh.v5i1.936

Abstract

The purpose of this study was to determine that the ethanolic extract of rambutan leaves (Nephelium lappaceum L) has antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria. As an antibacterial comparator used Amoxicillin. Each leaf of sample was extracted with maceration methode using 70% of ethanol solvent. Where it 2 to 3 days with several stirring times then it filtered, then the filtrate result was thickened with vacuum rotary evaporator. The antibacterial activity test used the paper disc diffusion method and was observed based on the diameter of the inhibition zone or the clear zone formed around the paper discs and slots which used with three times treatments. Result test of antibacterial activity of rambutan leaf ethanol extract (Nephelium lappaceum L) with these method showed that the extract actively inhibited the growth of Staphylococcus aureus bacteria with Minimum Inhibitory Concentration (MIC)3.125% with a 7.96 mm, but not showed for the growth of Escherichia coli bacteria.