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Journal : Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya

Effect of intermittent fasting diet on triglyceride levels in Sprague Dawley rats Esa Indah Ayudia; Andini Agustina; Huntari Harahap; Miftahurrahmah Miftahurrahmah; Irfannuddin Irfannuddin
JURNAL KEDOKTERAN DAN KESEHATAN Vol 8, No 2 (2021)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/V8I2.13576

Abstract

Triglycerides are the main lipid components that are stored in adipose tissue for energy sources. Increased triglyceride levels can lead to cardiovascular disease. One way to lower triglyceride levels is diet. The intermittent fasting diet is one of the diets that can be done, where this diet is a diet with time and calorie restrictions. The intermittent fasting diet is divided into 3 methods, namely Time restricted feeding, Alternate-day fasting and Modified fasting. This study was conducted to see the effect of an intermittent fasting diet on triglyceride levels. This research is an experimental study using white rats of Sprague Dawley strain as experimental. White rats will be divided into 3 groups of intermittent fasting diet and 1 control group and given a diet according to the group for 1 month. Weights and blood draws were performed at the beginning and end of the study, then the results of the intermittent fasting diet intervention were compared with the control group. There was a significant reduction in body weight with a p value of 0.000 and a significant decrease in triglyceride levels with a p value of 0.035 (p <0.05). Keywords : Triglycerides, Intermittent Fasting Diet, Weight loss. 
THE EFFECT OF INTERMITTENT FASTING 5:2 ON BODY FAT PERCENTAGE AND THICK UNDER-SKIN FAT FOLDS IN OVERWEIGHT AND OBESE INDIVIDUALS Esa Indah Ayudia; Miftahurrahmah; Indri Okta Sapitri; Huntari Harahap; Rina Nofri Enis; Hafizah
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 2 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i2.612

Abstract

Overweight and obesity is a condition in which there is an imbalance between the entry and exit of energy for a long time. Intermittent Fasting is one of the dietary interventions that can affect body composition such as body fat percentage and thick folds of fat under the skin. The purpose of this study was to determine the effect of Intermittent Fasting type 5:2 on body fat percentage and thick folds of fat under the skin in individuals with overweight and obesity. This study is an experimental study using pretest and posttest group design. The number of samples was 50 people with a consecutive sampling method. The statistical test used was the paired t-test. The results showed that intermittent fasting had a significant effect on body fat percentage (p<0.001), thick folds of fat under the skin of the biceps (p=0.009), and triceps (p<0.001), while the supra iliac and subscapular parts decreased but statistically insignificant (p=0.093) and (p=0.217).