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Journal : Jurnal Ilmu Kedokteran dan Kesehatan

A Case Report: Side Effect Of Linezolid In Pulmonary Rifampicin Resistance Tuberculosis Mustofa, Syazili; Karina, Salwa Al; Putri, Giska Tri; Busman, Hendri; Syakir, Muhammad Addin
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 1 (2025): Volume 12 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i1.18144

Abstract

Linezolid is a very potent treatment for pulmonary tuberculosis, but it has some side effects. Patients with drug-resistant pulmonary tuberculosis may experience anemia as a side effect of taking the multidrug-resistant tuberculosis medication Linezolid. A 58-year-old man's primary complaint in one case reported to RSUD dr. H. Abdul Moeloek Lampung was a weakness. The diagnosis was made based on anamnesis, a physical examination, and supporting examinations. Treatment was given both pharmacologically and non-pharmacologically, including the intervention to discontinue Linezolid. Although linezolid-based combination therapy in program conditions is associated with favorable outcomes, side effects should be monitored closely, which may require discontinuation of the drug and taking appropriate steps to treat side effects. 
A Case Report: Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbation Due To Community-Acquired Pneumonia (CAP) Infection In Smokers Mustofa, Syazili; Anggraeni, Liza; Putri, Giska Tri; Kurniawan, Betta; Agung Kurnia, Ahmad Fadila
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 1 (2025): Volume 12 Nomor 1
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i1.16265

Abstract

COPD, also know as Chronic Obstructive Pulmonary Disease, refers to a lung condition marked by persistent and progressive airflow blockage. This is usually the result of a chronic inflammatory reaction in the respiratory tract brought on by exposure to harmful gases or particles. Respiratory tract infections like Community-Acquired Pneumonia (CAP) frequently cause COPD exacerbations, while smoking is the main risk factor that contributes to the onset and worsening of COPD. The goal of this case report is to provide an understanding of the underlying mechanism of severe COPD cause by CAP infection in smokers and to diagnose and manage the condition effectively. A 72-year-old man complained of shortness of breath that he had been having for the last year, and that had worsened over the previous three days when he arrived at the emergency unit of Abdoel Moeloek Hospital in Lampung. In addition, he also had a fever and severe cough with yellow sputum. Following a comprehensive review of medical history, physical examination, and supporting examination, it was concluded that a CAP infection was linked to severe COPD exacerbation. The patient received antibiotic medication and hospitalization treatment for symptomatic therapy.