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Sinata, Novia
Sekolah Tinggi Ilmu Farmasi Riau
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Jurnal Farmasi Galenika

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Uji Aktivitas Antidiabetes Fraksi dari Ekstrak Etanol Daun Karamunting (Rhodomyrtus tomentosa (Ait.) Hassk.) Terhadap Mencit Diabetes Novia Sinata
JURNAL FARMASI GALENIKA Vol 3 No 2 (2016): Jurnal Farmasi Galenika Volume 3 No. 2, 2016
Publisher : Universitas Bhakti Kencana

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Abstract

Diabetes mellitus is a disease characterized by blood sugar levels that exceed normal (hyperglycemia) as a result of the body is insulin deficiency relative or absolute. Karamunting (Rhodomyrtus tomentosa (Ait.) Hassk.) one of the plants that are traditionally used to treat diabetes mellitus. The antidiabetic activity of plant karamunting because this plant contains chemical compounds, one of which is flavonoid. The Antidiabetic research of fraction of the ethanol extract of the leaves Karamunting (Rhodomyrtus tomentosa (Ait.) Hassk ) has been done on white male mice induced diabetes by alloxan dose of 200 mg / kg body weight intraperitoneally. The fraction of the extract ethanol was given ethyl acetate fraction, fraction of n-hexane and the fraction of water with each dose of 25 mg/ kg body weight given orally once daily for seven days. Parameters measured were blood glucose levels in mice. The results showed that the fraction of water orally showed a decrease in blood glucose levels are higher than diabetic mice by fractions of ethyl acetate and n-hexane fraction orally. The percentage of blood glucose lowering effect of the water fraction of 58.87%, 52.09% fraction of ethyl acetate and hexane fraction 24.30%.
Co-Authors Adela, Syarifah Nur Adriani Susanty Agistia, Nesa Agustini, Tiara Tri Al-Fadillah, Annsisya Shafira Alfiana, Heni Asnila Asnila Astaharie, Shinta Angelia Azhar, Gustika Azizah, Nur Rahmi Azli, Echa Saskia Dachriyanus Delvi Regika Deni Anggraini Dira Dira Dwi Pratiwi Emma Susanti Fatma Sri Wahyuni Ferdy Firmansyah Ferelina Santi Firstio Anfasa Mashudi Fitri Mulyani, Fitri Helmi Arifin Ihsan Ikhtiarudin Indah Denni Pratiwi Indah Wahyuni Indriana, Annisa Chika Ayu Intan Ayu Deswinda Kurnia, Lisa Laia, Cindy Oktaviana Leni Marlina Lestari, Maizurah Risa Lisa Renita M Almurdani Maisarah Maisarah Marisa Nurlita Meiriza Djohari, Meiriza Melanie, Claudy Friesta Mia Audina, Mia Mira Febrina Mistawati, Aida Musdalifah Musdalifah Muthui’ah Muthui’ah Nabela, Nabela Nadia, Putri Ningsih, Rizsari Nisa Aulia Nofriyanti Noveri Rahmawati Nurdina Putri Pratiwi, Erniza Pratiwi, Wulan Iska Rahimi, Indari Rahma Dona Ramadhani, Elsha Fadhika Dwi Ricardo, Nadira Atiqah Rizki, Famella Yustika Rosidi, Fatmarzuqni Putri Rusnedy, Rahmayati Sandra, Alya Dwi Satiya, Selin Faysa Shella Anggraini Siregar, Lisa Andriyani Siti Aisyah Rahmadani Suhada, Zikra Suwinda, Elia Syilfia Hasti Titik Maryani Wulandari, Lydia Tri Yadi, Hervi Zikrinnissa, Zikrinnissa