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All Journal Diponegoro International Medical Journal (DIMJ) Ophthalmologica Indonesiana
Maharani Cahyono
Department Of Ophthalmology, Faculty Of Medicine, Diponegoro University, Semarang, Indonesia
Health Professions Medicine & Pharmacology Neuroscience Public Health

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Journal : Ophthalmologica Indonesiana

 1 
Correlation of Intraocular Pressure Reduction and Frequency of Exercise Sara Listyani Koentjoro; Maharani Cahyono; Fifin Luthfia Rahmi
Majalah Oftalmologi Indonesia Vol 42 No 1 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i1.70

Abstract

Background: Intraocular pressure (IOP) is one of the primary risk factors of glaucoma. It is a modifiablerisk factor and can be affected by exercise. Some studies reported that physical exercise produced IOPreduction. The purpose of this study is to analyze the correlation between IOP reduction and frequencyof exercise.Methods: Thirty seven healthy subjects underwent IOP measurement on both eyes before andimmediately after 5 km of running. The frequency of exercise in a week was recorded and classifiedinto three groups: less than 2 times a week (group 1), 2-3 times a week (group 2), and more than 3times a week (group 3). IOP reductions were calculated and compared between groups. The data wereanalyzed with T-test for each group and ANOVA test for multivariate analysis.Results: There were 30 males and 7 females participated in this study. The mean age was 23.8±6.7years. After running up to 5 km, there was IOP reduction in each group frequency of exercise. Themean IOP reduction in group 1 was 0.20±2.5 mmHg (1.01%), in group 2 was 1.58±2.6 mmHg (8.60%),in group 3 was 1.31±3.0 mmHg (6.82%). IOP reductions in group 2 was statistically significant (p=0.019),compared to the other group. The multivariate analysis of three groups resulted in not significantcorrelation of IOP reduction and frequency of exercise (p=0.431).Conclusion: There was IOP reduction after running up to 5 km in each group frequency of exercise.However, there was no significant correlation of IOP reduction and frequency of exercise. Keywords: intraocular pressure, IOP, exercise
Intraocular Pressure Changes After Selective Laser Trabeculoplasty (SLT) in Open-Angle Glaucoma Amalia Mayasari; Maharani Cahyono
Majalah Oftalmologi Indonesia Vol 42 No 2 (2016): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v42i2.85

Abstract

Background: Selective laser trabeculoplasty (SLT) use laser to selectively target pigmented trabecularmeshwork without producing collateral damage to adjacent non-pigmented cells or structures. A previousdata suggests that SLT is effective at every stage of open-angle glaucoma (OAG). SLT can be used asa first-line therapy, alternative to medical therapy, or as an adjunctive therapy to topical glaucomadrops. The aim of this study was to determine the changes in intraocular pressure (IOP) after SLT inpatients with OAG.Methods: Design of this research was cohort-prospective study. Twenty-six eyes of 18 patients withOAG were participated in this study. All the patients were treated with 180o SLT to the temporaltrabecular meshwork and followed by 180o SLT to the nasal trabecular meshwork 1 week after the firsttreatment. A frequency-doubled (532 nm) Q-switched Nd:YAG laser with a 400 μm spot size wasused to deliver 0.4-1.0 mJ of energy for 0.3 ns to perform the procedure. Additionally, IOP in thetreated eye was assessed and measured with Goldman applanation before SLT, and 1 hour, 1 week,and 2 weeks following complete SLT. All patientes were given corticosteroid (prednisolone acetat 1%eyedrop) 4 times a day for 7 days after SLT to prevent elevation of IOP caused by inflammation.Results: The average pre-SLT IOP were 19.94 mmHg. The mean IOP 1 hour post-SLT was slightlyincrease. IOP 2 weeks after complete SLT showed a significant decrease compared to before SLT(Wilcoxon-test, before: p=0.033; 1 hour: p=0.915; 1 week: p=0.098; 2 weeks: p=0.009)Conclusion: Intraocular pressure lowering effect was significant at 2 weeks after SLT treatment. SLTeffectively reduces IOP in open-angle glaucoma. It can be used as a primary or adjunctive therapy inpatient with open-angle glaucoma.Keywords: obstructive MGD, quality of meibum, ocular surface damage
Co-Authors Amalia Mayasari Arnan Victor Wiryawan Dodik Dumadi Fifin Luthfia Rahmi Riski Prihatningtias Sara Listyani Koentjoro Tanti Ajoe Kesoema, Tanti Ajoe