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Journal : Jurnal Sumberdaya Hayati

Karakterisasi dan Potensi Antibakteri Ekstrak Kapang Endofit Hasil Isolasi dari Sargassum sp.: Characterization and Antibacterial Potential of Endophytic Fungi Extracts Isolated from Sargassum sp. Radiastuti, Nani; Bahri, Saiful; Muhammad, Alfianur Azmi; Dwikencana, Windy; Haribowo, Dinda Rama; Solihat, Nur Amaliah; Ramadhan, Firdaus; Ridhwan, Muhammad
Jurnal Sumberdaya Hayati Vol. 10 No. 4 (2024): 2024
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.10.4.183-189

Abstract

The bioactive potential in Sargassum sp. and its direct use is expected to reduce its population in nature if used continuously. Using endophytic fungi from the host is a solution for obtaining bioactive compounds from Sargassum sp. The purpose of this study was to characterize endophytic fungi in Sargassum sp. and its potential as an antibacterial agent. Endophytic fungi were isolated using the direct planting technique, endophytic fungi were characterized through microscopic and macroscopic observations. Extraction was performed with two organic solvents, namely ethanol and ethyl acetate. Antibacterial potency was tested using the agar diffusion method using Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Salmonella typhi. Based on the results, two mold isolates, D3P1 and D4P1, were obtained. The ethyl acetate extract of D3P1 had the highest inhibition zone for Bacillus subtilis bacteria, with the highest inhibition zone being 23.2 mm for Bacillus subtilis and the smallest being 17 mm for Escherichia coli. The ethyl acetate extract of D3P1 had the highest inhibition zone compared to the ethyl acetate extract of D4P1 and the ethanol extract of D3P1 and D4P1. The GC-MS analysis identified four compounds that have been identified in the ethyl acetate extract of D3P1 isolates, among others, 2,3-Butanediol, Phthalic acid, 1,2-Benzenedicarbocylic acid, and 1-Anthracenamine. Phthalic acid and 1,2-Benzenedicarboxylic acid compounds have the potential as antibacterial.
Potensi Waste Organic Product (WOP) FST 1310 terhadap Pertumbuhan Candida albicans Penyebab Kandidiasis: Potential of the Waste Organic Product (WOP) FST 1310 on the Growth of the Fungi Candida albicans Causes Candidiasis Ramadhan, Firdaus; Ghoza, Muhammad Radian; Haribowo, Dinda Rama; Sholeha, Dania Refia Riska; Kartika; Lestari, Anggita Rana Sasmita; Fikriwansyah, Aswir; Putri, Lily Surayya Eka; Ramadhani, Lidia Anggita; Sugoro, Irawan
Jurnal Sumberdaya Hayati Vol. 11 No. 1 (2025): 2025
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.11.1.8-15

Abstract

Candida albicans is an agent that causes candidiasis which can cause health problems in human’s organs. This study aims to determine the antifungal activity and inhibition zone diameter of Waste Organic Product (WOP) FST 1310 against Candida albicans. This type of research is experimental, using the Kirby-Bauer agar diffusion method with 6 treatments: P1: 100%, P2: 80%, P3: 60%, and P4: 40%, along with 2 controls, P5: nystatin (positive control) and P6: distilled water (negative control). The results showed that the WOP FST 1310 from orange peel had a larger inhibition zone diameter compared to the vegetable-derived. For the vegetable-derived eco-enzyme, the highest inhibition zone diameter was at a 100% concentration with an average of 3.7 mm. Meanwhile, for the orange peel eco-enzyme, the highest inhibition zone diameter was at a 40% concentration with an average of 5.3 mm.
Aktivitas Antibakteri Ekstrak Etanol Tangkai Daun Talas (Colocasia esculenta) Terhadap Bakteri Penyebab Jerawat Irianti, Ewith Ratih; Ramadhan, Firdaus; Noor, Susan Maphilindawati; Syafriana, Vilya; Ramadhani, Lidia Anggita
Jurnal Sumberdaya Hayati Vol. 11 No. 3 (2025): 2025
Publisher : Departemen Biologi, Institut Pertanian Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsdh.11.3.116-121

Abstract

Jerawat adalah penyakit kulit yang disebabkan oleh beberapa faktor, salah satunya infeksi bakteri Staphylococcus epidermidis. Pengobatan dengan bahan alam sudah banyak dilakukan untuk mengurangi efek samping penggunaan obat anti-jerawat. Talas memiliki khasiat sebagai obat dan berpotensi sebagai antibakteri. Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri ekstrak etanol 70% tangkai daun talas terhadap bakteri S. epidermidis dan senyawa bioaktif yang terkandung di dalamnya. Ekstrak dibuat dengan metode maserasi. Pengujian aktivitas antibakteri dengan metode difusi cakram dengan konsentrasi 0,5%; 1% ; 1,5%; 2%; dan 2,5% dengan klindamisin sebagai kontrol positif. Pengukuran zona bening atau diameter daya hambat (DDH) sebagai interpretasi data aktivitas antibakteri. Penapisan fitokimia meliputi alkaloid, flavonoid, saponin, terpenoid, steroid, dan tanin. Hasil pengujian aktivitas antibakteri menunjukkan terdapat zona bening pada semua konsentrasi kecuali 0,5%, dengan nilai rata-rata DDH masing-masing sebesar 17,33 mm; 20 mm; 25 mm; dan 27,67 mm. Nilai rata-rata DDH pada kontrol positif sebesar 47 mm. Berdasarkan penapisan fitokimia pada ekstrak etanol 70% tangkai daun talas memiliki hasil positif di semua uji. Ekstrak etanol 70% tangkai daun talas berpotensi sebagai antibakteri terhadap S. epidermidis dan memiliki senyawa-senyawa yang berpotensi sebagai bioaktif.
Co-Authors Ahmad Zulfikar Wicaksono Ahmad Zulfikar Wicaksono Aina Nadila Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin Alfan Farhan Rijaluddin, Alfan Farhan Alfianur Azmi Muhammad Amelia, Puteri Ardian Khairiah Ario Putro Pamungkas Arrum Sekar Diningrum Assuyuti, Yayan Mardiansyah Attamimi, Febi Irfaullah Aulia Fitri Firdausya Bahtiar, Nur Pajar Wahyu Dinda Rama Haribowo Dinda Rama Haribowo Dwi Cahya Kusuma Dwikencana, Windy Eka Putri, Lily Surayya Febrinita, Filda Fikriwansyah, Aswir Ghoza, Muhammad Radian Hajar Indra Wardhana Hariwibowo, Dinda Rama Haulani, Muttharif Arrabie Hutauruk, Hendra Johanes I Ketut Suada Indhina Reihannisa Indhina Reihannisa, Indhina Irawan Sugoro Irianti, Ewith Ratih Isral, Isral Jarudin Jarudin Kartika Lestari, Anggita Rana Sasmita Lily Surayya Eka Putri, Lily Surayya Eka Lukman, Jihan Fadhilah Mardi ansyah Mardiansyah Mardiansyah, Mardiansyah Marpaung, Albert Anggiat Petrus Mudrika, Dadan Muhammad Ikhsan Muhammad Ridhwan Muhammad, Alfianur Azmi Mujiyanto, Aldi Nani Radiastuti Naufal, Muhamad Nia Dzirwatul Izza Normala Rachmawati Nugraha, Slamet Nur Kholidah Nurkholidah Nurkholidah, Nurkholidah Pandu Kusuma, Abdi Pratiwi Amalia Zahrah Priyanti Priyanti Rachma Fauziah Rahayu Kusuma Ningrum Ramadhani, Lidia Anggita Ratih Mayangsari Reza Bayu Zikrillah Reza Bayu Zikrillah Riliansyah, Armar Rizky Aprizal Rosario T Manalu Ryandra, Raka Saiful Bahri Saiful Bahri Saiful Bahri Saiful Bahri Sari, Arina Findo Shalsabilla, Syalwa Ersadiwi Sholeha, Dania Refia Riska Siregar, Barharuddin Solihat, Nur Amaliah Sukarman Sukarman Susan Maphilindawati Noor Sutarman Sutarman Syifa Annisa Taqiyuddin Zanki Haidar Tokeshi, Mutsunori Yayan Mardiansyah Assuyuti