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All Journal Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmamedika (Pharmamedica Journal) Medical Sains : Jurnal Ilmiah Kefarmasian Medical Sains : Jurnal Ilmiah Kefarmasian
YUSLIA NOVIANI
UNIVERSITAS PANCASILA
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Ilmu Kefarmasian Indonesia

 1 
Pengaruh Variasi Konsentrasi Polivinil Alkohol (PVA) pada Formulasi Masker Gel Peel-Off Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) sebagai Anti Jerawat YUSLIA NOVIANI; SITI UMRAH NOOR; ERNI NENGSIH
JURNAL ILMU KEFARMASIAN INDONESIA Vol 14 No 2 (2016): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3272.656 KB)

Abstract

Buah belimbing wuluh (Averrhoa bilimbi L.) dapat digunakan sebagai anti jerawat karena kandungan flavonoid. Pengujian diameter daya hambat terhadap pertumbuhan bakteri Propionibacterium acnes dari ekstrak buah belimbing wuluh pada konsentrasi 8% memiliki daya hambat sebesar 8-9 mm. Ekstrak buah belimbing wuluh kemudian diformulasi menjadi masker gel peel-off dengan dosis ekstrak sebesar 8% sebagai anti jerawat, dibuat sebanyak tiga formula dengan variasi PVA 10, 12 dan 14%. Sediaan masker gel peel-off dibuat dengan metode pelarutan dan pencampuran, kemudian dievaluasi meliputi pengujian homogenitas, pengamatan visual, kekuatan tarikan, kecepatan waktu pengeringan, viskositas, sifat alir, uji aktivitas daya hambat terhadap pertumbuhan bakteri Propionibacterium acnes secara mikrobiologi.
EFFECT OF DRYING TECHNIQUE ON PHYSICAL QUALITY AND ANTI-INFLAMMATORY ACTIVITY OF WILD BETEL LEAVES (Piper sarmentosum Roxb. ex Hunter) EXTRACT Fahleni Fahleni; Yuslia Noviani; Syarifah Ramadhani
JURNAL ILMU KEFARMASIAN INDONESIA Vol 16 No 1 (2018): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1063.544 KB) | DOI: 10.35814/jifi.v16i1.436

Abstract

Kaduk betel leaves (Piper sarmentosum Roxb. ex. Hunter) contain flavonoids and alkaloids that have anti-inflammatory activity. Processing thick extract into a dry extract is required to determine the appropriate dose and increase the homogeneity. The purpose of tahhis study was to determine the effect of drying method to physical properties of dried powder and its antiinflammatory activity. Thick extract was dried using maltodextrin and lactose as adsorbents with concentrations of extract-adsorbent ratio 1: 1, 1: 2 and 1: 3. Method of drying were freeze drying and adsorbent. The evaluation results based on organoleptic dried powder, water content and flow properties. The water content of dried powder which is dried by freeze drying is smaller than that of the adsorbent. Organoleptic and flow properties of freeze dried powder results were also better. The best dried powder in each method tested its anti-inflammatory activity using BSA. The test results showed that the anti-inflammatory activity of dried extract of freeze drying (extract-maltodextrin 1:3) have higher activity with IC50 551.79 ppm compared to dried extract with adsorbent (extract-maltodextrin 1:3) 598.30 ppm.
Co-Authors Anarisa Budiati ERNI NENGSIH Fahleni Fahleni Isnaini Hidayanti Moch Futuchul Arifin Nurita Andayani Peggy Sri Astuti Rasta Naya Pratita SITI UMRAH NOOR Syarifah Ramadhani