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Journal : Jurnal Gizi dan Pangan

Pumpkin Soygurt Improves Blood Glucose Homeostasis in Diabetes Mellitus Rats Model Avelia, Annisa; Tamtomo, Didik Gunawan; Sari, Yulia
Jurnal Gizi dan Pangan Vol. 18 No. Supp.1 (2023)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2023.18.Supp.1.93-95

Abstract

The study aimed to analyze the effect of pumpkin yogurt on insulin resistance in a rat model. The experiment employed 30 male Wistar rats divided into six groups: three control groups (healthy, negative, and positive) and three treatment groups (metformin+PS 1 mL, 1.5 mL, 2 mL). The experiments were conducted for four weeks. Blood glucose homeostasis was measured by fasting blood glucose, insulin, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), and Quantitative Insulin-Sensitivity Check Index (QUICKI). Administrating a combination of metformin and pumpkin soygurt can control blood glucose homeostasis with an effective dose of 1 mL. Further research should be done on the hormone incretin, which plays a role in insulin secretion.
Potential Therapeutic Effects of Tali Bamboo Leaf Tea (Gigantochloa apus) on Lipid Profile of Rats With Metabolic Syndrome Mujayanah, Ani Rosa Putri Ayu; Sari, Yulia; Listyawati, Shanti
Jurnal Gizi dan Pangan Vol. 18 No. Supp.1 (2023)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2023.18.Supp.1.114-116

Abstract

This study aimed to determine the potential of Tali bamboo leaf tea (Gigantochloa apus) on the lipid profile of metabolic syndrome rats. This study is an laboratory-based experimental study using 30 male Wistar rats with metabolic syndrom aged 8 weeks and weighed 150–250 g, that were divided into 5 groups namely negative control (K-), positive control (K+), and three intervention groups with intervention doses of bamboo leaf tea at 300, 600, and 900 mg/200 g BW for 28 days. The results showed that there were significant differences (p<0.05) in High- Density Lipoprotein Cholesterol (HDL-C) and Low-Density Lipoprotein Cholesterol (LDL-C) levels before and after intervention. Tali bamboo leaf tea has the potential to improve the lipid profile of rats with metabolic syndrome (p<0.001).