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Journal : Jurnal Riset Kefarmasian Indonesia

UJI AKTIVITAS SITOTOKSIK EKSTRAK METANOL BUAH KETUMBAR (Coriandrum sativum Linn) TERHADAP ARTEMIA SALINA LEACH DENGAN UJI BSLT (Brine Shrimp Lethality Test) Yulia, Mega; Anggraini, Rani; Farizal, Farizal
Jurnal Riset Kefarmasian Indonesia Vol 2 No 3 (2020): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v2i3.72

Abstract

Coriander is a common herb can be used as traditional medicine. One of the expected benefits of Coriander fruits is an anti-cancer. This study aims to determine the cytotoxic activity of Coriander extract (Coriandrum sativum Linn) on shrimp larvae (Artemia salina Leach) with the BSLT (Brine Shrimp Lethality Test) method. Coriander fruits was extracted using methanol solvent and maceration method, then concentrated it with a rotary evaporator until a thick extract. Cytotoxic activity test used methanol extract with several concentration : 1,000 ppm, 100 ppm, 10 ppm, and 1 ppm. The result of this research reveal that methanol extract of Coriander fruits has cytotoxic activity with LC50 value is 32.35 ppm.
UJI KANDUNGAN TIMBAL (Pb) PADA GORENGAN YANG DIJUAL DI PINGGIR JALAN SEPANJANG PANTAI GANDORIAH PARIAMAN SECARA SPEKTROFOTOMETRI SERAPAN ATOM Yulia, Mega; Syahrianti, Dani; Yulis, Rahma
Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v3i1.118

Abstract

Lead is one of the heavy metal elements found in the air pollution which is produced together with motor vehicle fumes. Lead can cause various disorders in human body such as anemia, neurological damage, deformities and body functions, dental caries, impaired kidney function, effects on the heart and infertility. Lead can enter the human body through inhaled air, through the skin and ingested with food. The purpose of this study was to determine the lead content in fried foods (fried sala, fried crab, fried shrimp and fried fish) sale around of Gandoriah Beach, Pariaman. This research was conducted at Baristand Laboratory (Research and Standarirdization Industry Center) Padang from February until March 2020. This study was conducted on 4 samples taken randomly from the total population. The instrument used was atomic absorption spectrophotometry (AAS). The results of 4 samples showed that the lead content in fried sala was 0.1618 mg/kg, with a maximum SNI limit is 0.3 mg/kg, fried crab was 0.4025 mg/kg with a maximum SNI limit is 0,5 mg/kg, fried shrimp was 0.4377 mg/kg with a maximum SNI limit is 0.5 mg/kg, fried fish was 0.2331 mg/kg with an SNI maximum limit is 0.3 mg/kg. Based on the results of this study, it can be concluded all samples contain lead but the level is still below of maximum limit of SNI 7387-2009.
FORMULASI HARD CANDY DARI SARI BUAH JERUK NIPIS (Citrus aurantifolio), MADU (Mell depuratum) DAN KAYU MANIS (Cinnamomum burmanii) BERDASARKAN PERBEDAAN SIRUP GLUKOSA Yulia, Mega; Azra, Fadhilla Putri; Ranova, Riki
Jurnal Riset Kefarmasian Indonesia Vol 4 No 1 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i1.212

Abstract

Lime is a fruit that is widely used by people for treatment cough. For efficiency use of lime, it can processing to product that easier for using such as hard candy. This study aims to determine the results of physical tests and panelists preference for hard candies made from lime juice, honey and cinnamon. The method used is an experimental method by combining lime juice, honey, cinnamon and varying glucose syrup as a candy forming ingredient. Physical evaluation of each formula which includes analysis of water content and ash content, also hedonic test of 3 formulas to 100 panelists. The results of the physical evaluation carried out on the 3 formulas showed that all formulas met the quality requirements of SNI 3547.1:2008 hard candy for water content and ash content, also the results of the hedonic test using non parametric SPSS showed that there was a significant effect on taste and texture where formula III was the most preferred by panelist.
PERILAKU PENGGUNAAN ANTIBIOTIK TANPA RESEP DI APOTEK X DI KOTA PAYAKUMBUH SUMATERA BARAT Mega Yulia; Ruddy Parsono; Khairil Armal
Jurnal Riset Kefarmasian Indonesia Vol 4 No 3 (2022): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v4i3.264

Abstract

Antibiotic are organic compounds produced by various species of microorganisms and are toxic to other species of microorganisms. Irrational use of antibiotic can lead to resistance. The problem of resistance in addition to having an impact on morbidity and morality also has a very high economic and social impact. Research has been done on the behavior of using antibiotic without a prescription at pharmacy x in Payakumbuh City. The purpose of this study was to determine the use of antibiotic without a doctor's prescription at pharmacy X in Payakumbuh City. This research is non-experimental with data analyzed included the level of awareness of the use of antibiotic. The study used a descriptive method with random or accidental sampling with data collection using a questionnaire with 100 samples from 5296 populations. The results showed that the most widely used antibiotics were amoxicillin (46%); the type of disease that most patients treated with antibiotics was toothache (33%); the most sources of information about antibiotics came from friends or family (35%); the reason most people use antibiotics without a doctor's prescription is that previous treatment has a satisfactory effect (36%) and the level of patient awareness of the use of antibiotics is still in the sufficient category (42%).