Article Per Year (5 Year)
p-Index From 2020 - 2025
3.161
P-Index
This Author published in this journals
All Journal The Journal of Pure and Applied Chemistry Research Pharmascience Public Health of Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Media Analis Kesehatan JPSCR : Journal of Pharmaceutical Science and Clinical Research Lumbung Farmasi : Jurnal Ilmu Kefarmasian Humanism : Jurnal Pengabdian Masyarakat Jurnal Kesehatan Tambusai Jurnal Pengabdian kepada Masyarakat Jurnal EduHealth Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Mandiri Pharmaceutical Reports Pharmacology And Pharmacy Scientific Journals (PAPS Journals) MULTIPLE: Journal of Global and Multidisciplinary Jurnal Farmasi Galenika
Jangga
Universitas Megarezky
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

Published : 25 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : The Journal of Pure and Applied Chemistry Research

 1 
The Effect of Klika Ongkea Extract (Mezzetia parviflora Becc.) on Pancreatic β-Cells Regeneration by Streptozotocin-Induced in Wistar Rats Jangga - Jangga; Mansur - Mansur; Saparuddin - Latu
The Journal of Pure and Applied Chemistry Research Vol 11, No 1 (2022): Edition January-April 2022
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jpacr.2022.011.01.618

Abstract

This study aimed to determine the effect of Klika ongkea (Mezzetia parviflora Becc.) extract on the regeneration of pancreatic β-cells on Wistar rats that were induced using streptozotocin. Streptozotocin (STZ) with a 40 mg/kg BW dose was used in this study. Eighty adult male Wistar rats were used for this study. The animals were divided into four groups, Group I, as a healthy controls; Group II as an STZ-induced, Group III, STZ-induced and treated with galvus (Vildagliptin) 0.9 mg/200 g BW; Group IV, STZ-induced and treated with Klika ongkea 100 mg/kg BW. This study was conducted for 28 days. Four animals each group on the 1st, 7th, 14th, 21st and 28th days were observed to analyze the number of pancreatic β-cells. On the last day, pancreases were isolated and stained with hematoxylin & eosin (H&E) to analyze the regeneration of pancreatic β-cells. The data analysis was performed using an Independent-Sample T-Test to compare the number of pancreatic β-cells. The results showed that the administration of Klika ongkea extracts affected the pancreatic β-cells regeneration. These findings suggest that Klika ongkea has an effect on the regeneration of pancreatic β-cells in streptozotocin-induced rats.
Co-Authors Abdul Wahid Suleman Ainun Jariah Andi Muh Yagkin Padjalangi Andi Muhammad Yaqkin Padjalangi Andi Ulfah Magefirah Rasyid Anjani, Qonita Kurnia Ansari Masri Asnah Marzuki Faedatul Isma Farid, Nurfiddin Fitrianingsih, Julia Fityatun Usman Friska Adelia S Friska Adelia S Gajali, Nurdila Haerawati Idris Hairuddin K Hariati, Hariati Herman, Sriyana Ibtisamatul Aminah Kaisar Razak M.Akbar Ali Polanunu Mahmudah, Rifa’atul Mansur - Mansur Mawar Mawar Muhammad Guntur Muhammad Taufiq Duppa Muhammad Yusuf Musnur, Aldha Irjayanti Mustamin Muzayyidah Ningsih, Nining Ade Nur Fadhilah Nuradi Nuradi Nurdin, Mufliha Nurfadilah Nurhikmah Padjalangi, Andi Muhammad Yagkin Putri, Hardyanti Eka Qalby, Moch Noer Alim Qonita Kurnia Anjani Rahmadani Rahmadani Rifa’atul Mahmudah Rika Handayani Rosdiana Rosdiana Rusli Saparuddin Latu Siti Helmyati Sri Widyastuti Sri Wulan Rini Sulaiman Sulaiman Surya Syarifuddin Syafruddin Syafruddin Tamira Tansy Timbuleng Wira Anugrah Yulfina Wahdania Zulkifli Halid